Differential Ligand Activation of Estrogen Receptors ERα and ERβ at AP1 Sites

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

Cloning of a novel receptor expressed in rat prostate and ovary.

1996 • 4,782 citations

Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors α and β

1997 • 4,422 citations

The RXR heterodimers and orphan receptors

1995 • 3,168 citations

ERβ: Identification and characterization of a novel human estrogen receptor

1996 • 2,262 citations

Raloxifene (LY139481 HCI) prevents bone loss and reduces serum cholesterol without causing uterine hypertrophy in ovariectomized rats.

1994 • 614 citations

Effects of tamoxifen on uterus and ovaries of postmenopausal women in a randomised breast cancer prevention trial

1994 • 531 citations

Activation of the ovalbumin gene by the estrogen receptor involves the Fos-Jun complex

1990 • 486 citations

Identification of an Estrogen Response Element Activated by Metabolites of 17β-Estradiol and Raloxifene

1996 • 432 citations

Estrogen regulation of the insulin-like growth factor I gene transcription involves an AP-1 enhancer.

1994 • 390 citations

Identification of an estrogen response element upstream of the human c-fosgene that binds the estrogen receptor and the AP-1 transcription factor

1990 • 296 citations

Raloxifene, tamoxifen, nafoxidine, or estrogen effects on reproductive and nonreproductive tissues in ovariectomized rats

1996 • 285 citations

Antiestrogens. 2. Structure-activity studies in a series of 3-aroyl-2-arylbenzo[b]thiophene derivatives leading to [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl]-[4-[2-(1-piperidinyl)ethoxy]phenyl]methanone hydrochloride (LY 156758), a remarkably effective estrogen antagonist with only minimal intrinsic estrogenicity

1984 • 280 citations

The quinone reductase gene: A unique estrogen receptor-regulated gene that is activated by antiestrogens

1997 • 166 citations

Nuclear hormone receptors: ligand-activated regulators of transcription and diverse cell responses

1996 • 143 citations

Estrogen and raloxifene stimulate transforming growth factor-beta 3 gene expression in rat bone: a potential mechanism for estrogen- or raloxifene-mediated bone maintenance.

1996 • 137 citations

Tamoxifen: Teaching an old drug new tricks?

1996 • 123 citations