Functional Synergy between the Transcription Factor Sp1 and the Estrogen Receptor

MOLECULAR MECHANISMS OF ACTION OF STEROID/THYROID RECEPTOR SUPERFAMILY MEMBERS

1994 • 2,875 citations

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

1989 • 2,486 citations

Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase

1995 • 1,973 citations

Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation.

1996 • 992 citations

Steroid Receptor Family: Structure and Functions

1990 • 820 citations

Steroid Hormone Receptors: Interaction with Deoxyribonucleic Acid and Transcription Factors*

1993 • 724 citations

CDK-Independent Activation of Estrogen Receptor by Cyclin D1

1997 • 698 citations

Tamoxifen activation of the estrogen receptor/AP-1 pathway: potential origin for the cell-specific estrogen-like effects of antiestrogens.

1995 • 665 citations

The transcriptional control of hematopoiesis [see comments]

1996 • 608 citations

Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens.

1995 • 502 citations

Functional Synergy and Physical Interactions of the Erythroid Transcription Factor GATA-1 with the Krüppel Family Proteins Sp1 and EKLF

1995 • 475 citations

A 13 bp palindrome is a functional estrogen responsive element and interacts specifically with estrogen receptor

1988 • 439 citations

Identification of an Estrogen Response Element Activated by Metabolites of 17β-Estradiol and Raloxifene

1996 • 432 citations

Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

1995 • 431 citations

CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription.

1996 • 414 citations

Variant human breast tumor estrogen receptor with constitutive transcriptional activity.

1991 • 397 citations

Interaction of Sp1 with the Growth- and Cell Cycle-Regulated Transcription Factor E2F

1996 • 343 citations

Estrogen-responsive element of the human pS2 gene is an imperfectly palindromic sequence.

1989 • 330 citations

HTLV-I Tax Protein Stimulation of DNA Binding of bZIP Proteins by Enhancing Dimerization

1993 • 312 citations

Mechanism of estrogen activation of c-myc oncogene expression.

1992 • 300 citations

Identification of an estrogen response element upstream of the human c-fosgene that binds the estrogen receptor and the AP-1 transcription factor

1990 • 296 citations

Cooperation by Sterol Regulatory Element-binding Protein and Sp1 in Sterol Regulation of Low Density Lipoprotein Receptor Gene

1995 • 295 citations

Cell Cycle-Regulated Association of E2F1 and Sp1 Is Related to Their Functional Interaction

1996 • 268 citations

Promoter targeting by adenovirus E1a through interaction with different cellular DNA-binding domains

1994 • 256 citations

Estrogen receptor-Sp1 complexes mediate estrogen-induced cathepsin D gene expression in MCF-7 human breast cancer cells.

1994 • 247 citations

The human oxytocin gene promoter is regulated by estrogens.

1990 • 241 citations

Characterization of the hormone responsive element involved in the regulation of the progesterone receptor gene.

1991 • 238 citations

Identification of an estrogen-responsive element from the 5'-flanking region of the rat prolactin gene.

1987 • 231 citations

Ligand-dependent, transcriptionally productive association of the amino- and carboxyl-terminal regions of a steroid hormone nuclear receptor.

1995 • 209 citations

Functional Interactions, Phosphorylation, and Levels of 3′,5′-Cyclic Adenosine Monophosphate-Regulatory Element Binding Protein and Steroidogenic Factor-1 Mediate Hormone-Regulated and Constitutive Expression of Aromatase in Gonadal Cells

1997 • 209 citations

Molecular Mechanism of Inhibition of Estrogen-Induced Cathepsin D Gene Expression by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) in MCF-7 Cells

1995 • 205 citations

Cell-specific activity of a GGTCA half-palindromic oestrogen-responsive element in the chicken ovalbumin gene promoter.

1988 • 171 citations

Role of estrogen receptor/Sp1 complexes in estrogen-induced heat shock protein 27 gene expression.

1996 • 141 citations

Functional interaction of GATA1 with erythroid Kruppel-like factor and Sp1 at defined erythroid promoters

1996 • 139 citations

Estradiol and phorbol ester cause phosphorylation of serine 118 in the human estrogen receptor.

1995 • 139 citations

Ligand-dependent and -independent function of the transactivation regions of the human estrogen receptor in yeast.

1992 • 116 citations

An estrogen-responsive element mediates the transcriptional regulation of calbindin D-9K gene in rat uterus.

1991 • 115 citations

The Transcriptional Integrator CREB-Binding Protein Mediates Positive Cross Talk between Nuclear Hormone Receptors and the Hematopoietic bZip Protein p45/NF-E2

1997 • 107 citations

Promoter specificity of the two transcriptional activation functions of the human oestrogen receptor in yeast

1992 • 103 citations

Identification of an estrogen response element in the 3'-flanking region of the murine c-fos protooncogene.

1992 • 100 citations

The Uteroglobin Promoter Contains a Noncanonical Estrogen Responsive Element

1990 • 98 citations

Identification of a negative regulatory function for steroid receptors.

1992 • 98 citations

Two functional estrogen response elements are located upstream of the major chicken vitellogenin gene.

1988 • 93 citations

Estrogen response module of the mouse lactoferrin gene contains overlapping chicken ovalbumin upstream promoter transcription factor and estrogen receptor-binding elements.

1992 • 88 citations

Identification of an estrogen-responsive element in the rat LH beta gene. DNA-estrogen receptor interactions and functional analysis.

1991 • 86 citations

Estradiol regulation of the human retinoic acid receptor alpha gene in human breast carcinoma cells is mediated via an imperfect half-palindromic estrogen response element and Sp1 motifs.

1995 • 84 citations

Human estrogen receptor messenger RNA variants in both normal and tumor breast tissues

1995 • 75 citations

Delineation of sites mediating estrogen regulation of the rat creatine kinase B gene.

1992 • 69 citations

Transcriptional synergism between the vitamin D3 receptor and other nonreceptor transcription factors.

1994 • 68 citations

In vivo and in vitro phosphorylation of the human estrogen receptor

1995 • 66 citations

In vitro interaction of uterine estrogen receptor with the estrogen response element present in the 3′-flanking region of the murine c-fos protooncogene

1994 • 37 citations

Estrogen action in target cells: selective requirements for activation of different hormone response elements

1995 • 27 citations