Comparative study of the repair kinetics of chromosomal aberrations and DNA strand breaks in proliferating and quiescent

International Journal of Radiation Biology

1959 • 1,730 citations

Initial Events in the Cellular Effects of Ionizing Radiations: Clustered Damage in DNA

1994 • 1,142 citations

DNA double-strand breaks measured in individual cells subjected to gel electrophoresis.

1991 • 330 citations

Mechanisms of nonhomologous recombination in mammalian cells.

1985 • 314 citations

Molecular mechanisms involved in the production of chromosomal aberrations

1984 • 303 citations

The Rate of Strand Separation in Alkali of DNA of Irradiated Mammalian Cells

1975 • 248 citations

Review of repair kinetics for DNA damage induced in eukaryotic cells in vitro by ionizing radiation

1989 • 206 citations

The Rate of Strand Separation in Alkali of DNA of Irradiated Mammalian Cells

2012 • 197 citations

Clusters of DNA induced by ionizing radiation: formation of short DNA fragments. I. Theoretical modeling.

1996 • 166 citations

Kinetics of DNA Double-strand Break Repair Throughout the Cell Cycle as Assayed by Pulsed Field Gel Electrophoresis in CHO Cells

1991 • 152 citations

Potentially Lethal Damage versus Sublethal Damage: Independent Repair Processes in Actively Growing Chinese Hamster Cells

1979 • 129 citations

Measurement of the Kinetics of DNA Double Strand Break Repair in Ehrlich Ascites Tumour Cells Using the Unwinding Method

1980 • 116 citations

Use of Restriction Endonucleases to Study Relationships between DNA Double-strand Breaks, Chromosomal Aberrations and Other End-points in Mammalian Cells

1988 • 112 citations

Double-strand break repair and G2 block in Chinese hamster ovary cells and their radiosensitive mutants

1985 • 94 citations

Radiation induced DNA double strand breaks are rejoined by ligation and recombination processes

1981 • 86 citations

Three Classes of DNA Strand Breaks Induced by X-irradiation and Internal β-rays

1986 • 83 citations

Relative Contributions of Levels of Initial DNA Damage and Repair of Double Strand Breaks to the Ionizing Radiation-sensitive Phenotype of the Chinese Hamster Cell Mutant, XR-V15B. Part I. X-rays

1993 • 82 citations

DNA double-strand break repair pathways and cellular tolerance to inhibitors of topoisomerase II.

1990 • 80 citations

Comparison of DNA Double-strand Break Rejoining as Measured by Pulsed Field Gel Electrophoresis, Neutral Sucrose Gradient Centrifugation and Non-unwinding Filter Elution in Irradiated Plateau-phase CHO Cells

1991 • 72 citations

Thermally Enhanced Radioresponse of Cultured Chinese Hamster Cells: Damage and Repair of Single-Stranded DNA and a DNA Complex

1974 • 67 citations

The Relationship between Cell Killing, Chromosome Aberrations, Spindle Defects and Mitotic Delay in Mouse Lymphoma Cells of Differential Sensitivity to X-rays

1980 • 63 citations

Evidence for a dose-squared term in the dose-response curve for real chromatid discontinuities induced by X-rays, and some theoretical consequences thereof

1966 • 61 citations

The induction of chromosome aberrations by restriction endonucleases that produce blunt-end or cohesive-end double-strand breaks

1988 • 61 citations

Hypothesis. Elkind recovery and “sub-lethal damage”: a misleading association?

1977 • 60 citations

Level of DNA Double-strand Break Rejoining in Chinese Hamsterxrs-5 Cells is Dose-dependent: Implications for the Mechanism of Radiosensitivity

1992 • 52 citations

¹²⁵IdUrd-induced Chromosome Fragments, Assayed by Premature Chromosome Condensation, and DNA Double-strand Breaks Have Similar Repair Kinetics in G₁-phase CHO-cells

1987 • 51 citations

Effect of Arabinofuranosyladenine on Radiation-Induced Chromosome Damage in Plateau-Phase CHO Cells Measured by Premature Chromosome Condensation: Implications for Repair and Fixation of α-PLD

1988 • 45 citations

Kinetics of the Formation of Chromosome Aberrations in X-Irradiated Human Lymphocytes: Analysis by Premature Chromosome Condensation with Delayed Fusion

1995 • 44 citations

Detection of DNA Damage in Cells Exposed to Ionizing Radiation by Use of Anti-single-stranded DNA Monoclonal Antibody

1989 • 43 citations

DNA repair kinetics after exposure to X-irradiation and to internal?-rays in CHO cells

1986 • 43 citations

Molecular recombination and the repair of DNA double-strand breaks in CHO cells

1979 • 42 citations

Ionizing radiation induced DNA lesions which lead to chromosomal aberrations

1993 • 37 citations

Hypertonic Treatment during Premature Chromosome Condensation Allows Visualization of Interphase Chromosome Breaks Repaired with Fast Kinetics in Irradiated CHO Cells

1993 • 37 citations

Reparable and Non-reparable DNA Strand Breaks Induced by X-irradiation in CHO K1 Cells and the Radiosensitive Mutantsxrs1andxrs5

1993 • 36 citations

Elkind recovery and “sub-lethal damage”: a misleading association?

1978 • 31 citations

Recovery kinetics of radiation-induced chromosome aberrations in human G0 lymphocytes

1980 • 29 citations

Decreased Repair of Radiation-Induced DNA Double-Strand Breaks with Cellular Differentiation

1992 • 27 citations

Single-strand Break Disappearance in Quiescent and Phytohaemagglutinin-stimulated Human Peripheral Blood Lymphocytes Exposed to a Single Low Dose of γ-radiation

1992 • 18 citations

Reversibility of Inhibition of DNA Double Strand Break Repair by 2-Deoxy-<scp>d</scp>-Glucose in Ehrlich Ascites Tumour Cells

1993 • 16 citations

Kinetics of Chromosome Lesion Repair in Synchronized Quiescent and Proliferating CHO Cells

1990 • 12 citations

Comparison between the Alkaline Unwinding Technique and Neutral Filter Elution Using CHO, V79 and EAT Cells

1995 • 10 citations

Chromosomal aberrations induced by the restriction endonucleases EcoR I, Pst I, Sal I and Bam HI in CHO cells

1987 • 10 citations

Repair of Potentially Mutagenic Damage, Sensitive to Anisotonic Treatment, in Actively Growing Chinese Hamster Cells

1988 • 8 citations

Kinetics of cell survival as predicted by the repair/interaction model.

1984 • 5 citations

Effects of Daunomycin and Radiation on Cell-survival and Repair of DNA Single-strand Breaks

1977 • 4 citations