Simulation of the distribution of chromosome targets in cell nuclei under topological constraints

Fluorescence in situ hybridization with human chromosome-specific libraries: detection of trisomy 21 and translocations of chromosome 4.

1988 • 1,334 citations

Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries

1988 • 1,171 citations

Monte Carlo Simulation in Statistical Physics: An Introduction

2002 • 681 citations

Macromolecular Domains within the Cell Nucleus

1993 • 611 citations

Parameters of the human genome.

1991 • 521 citations

The rationale for an ordered arrangement of chromatin in the interphase nucleus.

1968 • 358 citations

A view of Interphase Chromosomes

1990 • 341 citations

A Three-Dimensional View of Precursor Messenger RNA Metabolism Within the Mammalian Nucleus

1993 • 335 citations

A random-walk/giant-loop model for interphase chromosomes.

1995 • 306 citations

Reproducible compartmentalization of individual chromosome domains in human CNS cells revealed by in situ hybridization and three-dimensional reconstruction

1988 • 279 citations

Individual interphase chromosome domains revealed by in situ hybridization

1985 • 274 citations

Rabl's model of the interphase chromosome arrangement tested in Chinise hamster cells by premature chromosome condensation and laser-UV-microbeam experiments

1982 • 271 citations

Evidence for a nuclear compartment of transcription and splicing located at chromosome domain boundaries

1993 • 241 citations

Analysis of genes and chromosomes by nonisotopic in situ hybridization

1991 • 240 citations

Specific staining of human chromosomes in Chinese hamster x man hybrid cell lines demonstrates interphase chromosome territories

1985 • 231 citations

Three-dimensional reconstruction of painted human interphase chromosomes: active and inactive X chromosome territories have similar volumes but differ in shape and surface structure.

1996 • 218 citations

Chromosome topology in mammalian interphase nuclei

1991 • 206 citations

Cell cycle dependent chromosomal movement in pre-mitotic human T-lymphocyte nuclei

1992 • 154 citations

The internal order of the interphase nucleus

1974 • 109 citations

Nuclear architecture in plants

1990 • 104 citations

Sex chromosome positions in human interphase nuclei as studied by in situ hybridization with chromosome specific DNA probes

1984 • 83 citations

Polymer models for interphase chromosomes.

1993 • 80 citations

Distribution of chromosome 18 and X centric heterochromatin in the interphase nucleus of cultured human cells

1990 • 74 citations

The Interphase Nucleus as a Dynamic Structure

1994 • 60 citations

Characterization of centromere arrangements and test for random distribution in G0, G1, S, G2, G1, and early S′ phase in human lymphocytes

1992 • 56 citations

Three-dimensional analysis of the organization of human chromosome domains in human and human-hamster hybrid interphase nuclei

1989 • 52 citations

Differences of size and shape of active and inactive X‐chromosome domains in human amniotic fluid cell nuclei

1993 • 39 citations

A versatile 2π‐tilting device for fluorescence microscopes

1994 • 31 citations

The localization of chromosome domains in human interphase nuclei. Three-dimensional distance determinations of fluorescence in situ hybridization signals from confocal laser scanning microscopy

1993 • 27 citations

Three-dimensional distribution of centromeric or paracentromeric heterochromatin of chromosomes 1, 7, 15 and 17 in human lymphocyte nuclei studied with light microscopic axial tomography

1995 • 26 citations

[Non-random position of homologous chromosomes (no. 9 and YY) in interphase nuclei of human fibroblasts (author's transl)].

1975 • 22 citations

Three-dimensional analysis of Mica Dam

1974 • 11 citations

Deleted Work

1955 • 0 citations