A newly established metastatic breast tumor cell line with integrated amplified copies of ERBB2 and double minute chromosomes

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

1987 • 11,429 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

A Human Cell Line From a Pleural Effusion Derived From a Breast Carcinoma 2

1973 • 2,431 citations

Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes

1980 • 1,884 citations

Localization of mitochondria in living cells with rhodamine 123.

1980 • 1,529 citations

Localization of single copy DNA sequences on G-banded human chromosomes by in situ hybridization

1981 • 836 citations

The human c-myc oncogene: Structural consequences of translocation into the igh locus in Burkitt lymphoma

1983 • 732 citations

Gene amplification in cultured animal cells

1984 • 639 citations

Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms.

1987 • 619 citations

Inactivation of the Retinoblastoma Susceptibility Gene in Human Breast Cancers

1988 • 608 citations

Differential Reactivity of a Novel Monoclonal Antibody (DF3) with Human Malignant versus Benign Breast Tumors

1984 • 583 citations

Correlation of c-erbB-2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading.

1988 • 570 citations

Serum-free growth of human mammary epithelial cells: rapid clonal growth in defined medium and extended serial passage with pituitary extract.

1984 • 435 citations

Structural Rearrangement of the Retinoblastoma Gene in Human Breast Carcinoma

1988 • 423 citations

Unusual retention of rhodamine 123 by mitochondria in muscle and carcinoma cells.

1982 • 356 citations

Human breast carcinoma cells in continuous culture: a review.

1978 • 345 citations

Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types.

1989 • 266 citations

The importance of circular DNA in mammalian gene amplification.

1989 • 234 citations

Egf binding to its receptor triggers a rapid tyrosine phosphorylation of the erbB-2 protein in the mammary tumor cell line SK-BR-3.

1988 • 226 citations

An improved method for G-banding chromosomes after in situ hybridization

1984 • 132 citations

Growth requirements of human mammary epithelial cells in culture

1977 • 130 citations

Relationship between gene amplification and chromosomal deviations in malignant human gliomas

1987 • 129 citations

Expression of growth factors and oncogenes in normal and tumor-derived human mammary epithelial cells.

1988 • 116 citations

Clonal proliferation of cultured nonmalignant and malignant human breast epithelia.

1981 • 108 citations

The significance of oncogene amplification in primary breast cancer

1989 • 94 citations

Understanding Breast Cancer: Clinical and Laboratory Concepts

1984 • 79 citations

The biology of breast cancer at the cellular level

1984 • 64 citations

The role of class I histocompatibility antigens in the regulation of T-cell activation.

1987 • 56 citations

Genetic analysis of tumorigenesis: a conserved region in the human and Chinese hamster genomes contains genetically identified tumor-suppressor genes.

1987 • 27 citations

A monoclonal antibody recognizing a keratin filament protein in a subset of transitional and glandular epithelia

1984 • 15 citations

Human Breast Cancer Markers Defined by Monoclonal Antibodies

1985 • 7 citations