Connective Tissue Growth Factor Is Crucial to Inducing a Profibrotic Environment in “Fibrosis-Resistant” Balb/c Mouse Lungs

Idiopathic Pulmonary Fibrosis: Prevailing and Evolving Hypotheses about Its Pathogenesis and Implications for Therapy

2001 • 1,727 citations

Determination of hydroxyproline

1967 • 1,583 citations

Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung.

1997 • 1,010 citations

Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-β

2002 • 866 citations

Stimulation of Fibroblast Cell Growth, Matrix Production, and Granulation Tissue Formation by Connective Tissue Growth Factor

1996 • 754 citations

An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.

1994 • 743 citations

Connective tissue growth factor: a mediator of TGF-β action on fibroblasts

1997 • 743 citations

Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair.

1993 • 706 citations

Connective Tissue Growth Factor: What's in a Name?

2000 • 483 citations

Role and interaction of connective tissue growth factor with transforming growth factor-? in persistent fibrosis: A mouse fibrosis model

1999 • 461 citations

Connective tissue growth factor mRNA expression is upregulated in bleomycin-induced lung fibrosis

1998 • 242 citations

Thrombin Is a Potent Inducer of Connective Tissue Growth Factor Production via Proteolytic Activation of Protease-activated Receptor-1

2000 • 234 citations

Serum levels of connective tissue growth factor are elevated in patients with systemic sclerosis: association with extent of skin sclerosis and severity of pulmonary fibrosis.

2000 • 227 citations

Alterations in pulmonary mRNA encoding procollagens, fibronectin and transforming growth factor-beta precede bleomycin-induced pulmonary fibrosis in mice.

1988 • 199 citations

Type II alveolar epithelial cells and interstitial fibroblasts express connective tissue growth factor in IPF

2001 • 192 citations

Transient Transgene Expression of Decorin in the Lung Reduces the Fibrotic Response to Bleomycin

2001 • 184 citations

Future Research Directions in Idiopathic Pulmonary Fibrosis

2002 • 183 citations

Enhanced Insulin-Like Growth Factor Binding Protein–Related Protein 2 (Connective Tissue Growth Factor) Expression in Patients with Idiopathic Pulmonary Fibrosis and Pulmonary Sarcoidosis

1999 • 182 citations

Radiation-Induced Pulmonary Fibrosis: Examination of Chemokine and Chemokine Receptor Families

2002 • 174 citations

Differences in the Fibrogenic Response after Transfer of Active Transforming Growth Factor-β1 Gene to Lungs of “Fibrosis-prone” and “Fibrosis-resistant” Mouse Strains

2002 • 171 citations

Re-evaluation of Fibrogenic Cytokines in Lung Fibrosis

2003 • 162 citations

Increased expression of transforming growth factor beta isoforms (beta 1, beta 2, beta 3) in bleomycin-induced pulmonary fibrosis.

1995 • 135 citations

Adenoviral Gene Transfer of Connective Tissue Growth Factor in the Lung Induces Transient Fibrosis

2003 • 131 citations

Interstitial fibrosis and growth factors.

2000 • 129 citations

Immunohistochemical Localization of Transforming Growth Factor β and Tumor Necrosis Factor α in the Lungs of Fibrosis-Prone and "Non-Fibrosing" Mice during the Latent Period and Early Phase after Irradiation

1997 • 120 citations

Differences in Correlation of mRNA Gene Expression in Mice Sensitive and Resistant to Radiation-Induced Pulmonary Fibrosis

1995 • 103 citations

Pulmonary Fibrosis

2000 • 79 citations

Susceptibility to Asbestos-Induced and Transforming Growth Factor-β₁–Induced Fibroproliferative Lung Disease in Two Strains of Mice

2002 • 48 citations

Idiopathic pulmonary fibrosis. New insights into classification and pathogenesis usher in a new era therapeutic approaches.

2003 • 42 citations

Profiling of genes which are differentially expressed in mouse liver in response to adenoviral vectors and delivered genes

2000 • 35 citations

The Genetic Predisposition to Interstitial Lung Disease

2002 • 31 citations

Sarcoidosis

2002 • 17 citations