Chromosome methylation patterns during mammalian preimplantation development

Manipulating the mouse embryo: A laboratory manual

1986 • 4,548 citations

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

1992 • 3,907 citations

CpG-rich islands and the function of DNA methylation

1986 • 3,760 citations

Cytosine methylation and the ecology of intragenomic parasites

1997 • 1,906 citations

Genetic variants and strains of the laboratory mouse

1990 • 1,519 citations

An Air-Drying Method for Chromosome Preparations from Mouse Eggs

1966 • 1,145 citations

Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development

1987 • 1,088 citations

Number of CpG islands and genes in human and mouse.

1993 • 986 citations

Microfluorometric Detection of Deoxyribonucleic Acid Replication in Human Metaphase Chromosomes

1973 • 838 citations

Spl elements protect a CpG island from de novo methylation

1994 • 713 citations

Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation.

1994 • 667 citations

Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island.

1994 • 597 citations

5-Methylcytosine, Gene Regulation, and Cancer

1983 • 425 citations

Differential H4 acetylation of paternal and maternal chromatin precedes DNA replication and differential transcriptional activity in pronuclei of 1-cell mouse embryos

1997 • 421 citations

Methylation levels of maternal and paternal genomes during preimplantation development

1991 • 309 citations

DNA methylation in early development

1995 • 283 citations

Differences in DNA methylation during oogenesis and spermatogenesis and their persistence during early embryogenesis in the mouse.

1987 • 278 citations

Methylation of Genomes and Genes at the Invertebrate-Vertebrate Boundary

1997 • 249 citations

Properties and localization of DNA methyltransferase in preimplantation mouse embryos: implications for genomic imprinting.

1992 • 228 citations

The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse

1996 • 227 citations

Differential spiralization along mammalian mitotic chromosomes

1972 • 220 citations

Differential distribution of long and short interspersed element sequences in the mouse genome: chromosome karyotyping by fluorescence in situ hybridization.

1990 • 199 citations

Alu: Structure, Origin, Evolution, Significance, and Function of One-Tenth of Human DNA

1996 • 190 citations

DNA Demethylation In Vitro: Involvement of RNA

1996 • 188 citations

Reporter Gene Expression in G2 of the 1-Cell Mouse Embryo

1993 • 182 citations

Abnormal methylation pattern in constitutive and facultative (X inactive chromosome) heterochromatin of ICF patients

1994 • 141 citations

Mechanistic aspects of genome-wide demethylation in the preimplantation mouse embryo.

1993 • 138 citations

Requirements for Promoter Activity in Mouse Oocytes and Embryos Distinguish Paternal Pronuclei from Maternal and Zygotic Nuclei

1993 • 133 citations

Methylation patterns of repetitive DNA sequences in germ cells ofMus muscutus

1984 • 126 citations

Microsatellite mapping of the gene causing weaver disease in cattle will allow the study of an associated quantitative trait locus.

1993 • 123 citations

Monitoring of urinary excretion of modified nucleosides in cancer patients using a set of six monoclonal antibodies

1992 • 116 citations

Alu repeated DNAs are differentially methylated in primate germ cells

1994 • 107 citations

An embryonic demethylation mechanism involving binding of transcription factors to replicating DNA

1998 • 102 citations

DNA methylation and embryogenesis

1993 • 77 citations

Specific Alu Binding Protein from Human Sperm Chromatin Prevents DNA Methylation

1995 • 52 citations

The ability to organize sperm DNA into functional chromatin is acquired during meiotic maturation in murine oocytes

1997 • 44 citations

Undermethylation of Alu sequences in ICF syndrome: molecular and in situ analysis

1997 • 37 citations

Steroid hormone dependent changes in DNA methylation and its significance for the activation or silencing of specific genes

1993 • 22 citations

Differential inhibition of sister chromatid condensation induced by 5-azadeoxycytidine in human chromosomes

1986 • 13 citations

Polymerase chain reaction products containing 5-methyldeoxycytidine: a microplate immunoquantitation method

1994 • 7 citations