Soluble peptidoglycan-induced monokine production can be blocked by anti-CD14 monoclonal antibodies and by lipid A partial structures

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding Protein

1990 • 4,041 citations

Peptidoglycan types of bacterial cell walls and their taxonomic implications

1972 • 3,772 citations

T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity

1978 • 3,314 citations

Structure and Function of Lipopolysaccharide Binding Protein

1990 • 1,689 citations

Biology of interleukin 1

1988 • 1,547 citations

Antigens on human monocytes identified by monoclonal antibodies.

1981 • 583 citations

Isolation of a lipopolysaccharide-binding acute phase reactant from rabbit serum.

1986 • 549 citations

Bacterial lipopolysaccharide and inflammatory mediators augment IL-6 secretion by human endothelial cells.

1989 • 470 citations

Lipopolysaccharide (LPS) binding protein opsonizes LPS-bearing particles for recognition by a novel receptor on macrophages.

1989 • 353 citations

Identification of a Lipid A Binding Site in the Acute Phase Reactant Lipopolysaccharide Binding Protein

1989 • 351 citations

Biochemical characterization of a soluble form of the 53‐kDa monocyte surface antigen

1986 • 256 citations

Plasma lipopolysaccharide (LPS)-binding protein. A key component in macrophage recognition of gram-negative LPS.

1992 • 224 citations

Total synthesis of escherichia coli lipid A

1985 • 179 citations

Specific endotoxic lipopolysaccharide-binding proteins on murine splenocytes. I. Detection of lipopolysaccharide-binding sites on splenocytes and splenocyte subpopulations.

1988 • 173 citations

Recognition of Bacterial Endotoxins by Receptor-Dependent Mechanisms

1993 • 159 citations

Specific endotoxic lipopolysaccharide-binding proteins on murine splenocytes. II. Membrane localization and binding characteristics.

1988 • 111 citations

Biological Properties of Peptidoglycan

1986 • 85 citations

Chemical Synthesis of a Biosynthetic Precursor of Lipid A with a Phosphorylated Tetraacyl Disaccharide Structure

1987 • 79 citations

Specific endotoxic lipopolysaccharide-binding receptors on murine splenocytes. III. Binding specificity and characterization.

1991 • 71 citations

Peptidoglycan and lipopolysaccharide bind to the same binding site on lymphocytes.

1991 • 67 citations

Agonists and antagonists for lipopolysaccharide-induced cytokines

1993 • 64 citations

Demonstration of peptidoglycan-binding sites on lymphocytes and macrophages by photoaffinity cross-linking.

1991 • 58 citations

Endotoxin-like properties of the peptidoglycan.

1975 • 57 citations

Polyclonal activation of immunoglobulin secretion in B lymphocytes induced by staphylococcal peptidoglycan.

1980 • 56 citations

Modulation of endotoxin-induced monokine release in human monocytes by lipid A partial structures that inhibit binding of 125I-lipopolysaccharide

1992 • 53 citations

Inhibition of endotoxin-induced interleukin-6 production by synthetic lipid A partial structures in human peripheral blood mononuclear cells

1991 • 50 citations

Mitogenic activity of staphylococcal peptidoglycan

1979 • 47 citations

Modulation of lipopolysaccharide-induced production of tumor necrosis factor, interleukin 1, and interleukin 6 by synthetic precursor Ia of lipid A

1992 • 46 citations

Biological activity of synthetic phosphonooxyethyl analogs of lipid A and lipid A partial structures

1992 • 44 citations

Regulatory Mechanisms of Host Responsiveness to Endotoxin (Lipopolysaccharide)

1991 • 40 citations

Detection of Interleukin 1 with Human Dermal Fibroblasts

1989 • 39 citations

Molecular Aspects of the Chemistry and Biology of Endotoxin

1991 • 32 citations

Suppressive effect of lipid A partial structures on lipopolysaccharide or lipid A-induced release of interleukin 1 by human monocytes

1990 • 28 citations

Identification and Characterization of Mammalian Cell Membrane Receptors for LPS-Endotoxin

1992 • 7 citations