Identification and Characterization of Mammalian Cell Membrane Receptors for LPS-Endotoxin

CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding Protein

1990 • 4,041 citations

Adhesion-promoting receptors on human macrophages recognize Escherichia coli by binding to lipopolysaccharide.

1986 • 415 citations

Specific endotoxic lipopolysaccharide-binding proteins on murine splenocytes. I. Detection of lipopolysaccharide-binding sites on splenocytes and splenocyte subpopulations.

1988 • 173 citations

Lipid A binding sites in membranes of macrophage tumor cells.

1988 • 112 citations

Synthesis and biochemical characterization of a photoactivatable, iodinatable, cleavable bacterial lipopolysaccharide derivative.

1985 • 100 citations

CD18-deficient cells respond to lipopolysaccharide in vitro.

1990 • 82 citations

Endotoxic-lipopolysaccharide-specific binding proteins on lymphoid cells of various animal species: association with endotoxin susceptibility

1989 • 72 citations

Specific endotoxic lipopolysaccharide-binding receptors on murine splenocytes. III. Binding specificity and characterization.

1991 • 71 citations

Identification of lipopolysaccharide-binding proteins in 70Z/3 cells by photoaffinity cross-linking.

1990 • 68 citations

Peptidoglycan and lipopolysaccharide bind to the same binding site on lymphocytes.

1991 • 67 citations

Isolation of a lipopolysaccharide (LPS)-resistant mutant, with defective LPS binding, of cultured macrophage-like cells.

1990 • 60 citations

Demonstration of peptidoglycan-binding sites on lymphocytes and macrophages by photoaffinity cross-linking.

1991 • 58 citations

Induction of macrophage-mediated tumor cytotoxicity by a hamster monoclonal antibody with specificity for lipopolysaccharide receptor.

1990 • 53 citations

Generation and characterization of hamster-mouse hybridomas secreting monoclonal antibodies with specificity for lipopolysaccharide receptor.

1990 • 53 citations

Identification and characterization of lipopolysaccharide-binding proteins on human peripheral blood cell populations

1992 • 44 citations

Monoclonal Antibody to Mouse Lipopolysaccharide Receptor Protects Mice against the Lethal Effects of Endotoxin

1990 • 37 citations

Gram-negative Endotoxin: A Biologically Active Lipid

1988 • 33 citations