Chemical Synthesis of a Biosynthetic Precursor of Lipid A with a Phosphorylated Tetraacyl Disaccharide Structure

Chemische Erforschung von Lipopolysacchariden gramnegativer Bakterien

1954 • 618 citations

Electrodialysis of Lipopolysaccharides and Their Conversion to Uniform Salt Forms

1975 • 359 citations

Endotoxic properties of chemically synthesized lipid A part structures. Comparison of synthetic lipid A precursor and synthetic analogues with biosynthetic lipid A precursor and free lipid A

1984 • 180 citations

Total synthesis of escherichia coli lipid A

1985 • 179 citations

Chemical structure of Lipid A: Linkage site of acyl groups in the disaccharide backbone

1983 • 130 citations

Chemical structure of lipid A

1985 • 120 citations

Location of polar substituents and fatty acyl chains on lipid A precursors from a 3-deoxy-D-manno-octulosonic acid-deficient mutant of Salmonella typhimurium. Studies by 1H, 13C, and 31P nuclear magnetic resonance.

1985 • 105 citations

Chemical synthesis of phosphorylated tetraacyl disaccharide corresponding to a biosynthetic precursor of lipid A

1984 • 104 citations

Isolation, Purification and Properties of an Intermediate in 3-Deoxy-d-manno-octulosonic Acid-Lipid A Biosynthesis

1977 • 70 citations

Immunobiologically active lipid A analogs synthesized according to a revised structural model of natural lipid A

1984 • 66 citations

Biological activities of analogues of lipid A based chemically on the revised structural model

1984 • 51 citations

Total synthesis of antibiotic streptothricin F

1982 • 35 citations

Synthetic approach to lipid A: Preparation of phosphorylated disaccharides containing (R)-3-hydroxyacyl and (R)-3-acyloxyacyl groups

1983 • 29 citations

Free flow electrophoresis as a tool for enrichment of mutants with temperature-dependent lethal mutations in lipid A synthesis

1985 • 24 citations