Helper T cell differentiation enters a new era: Le Roi est mort; vive le Roi!

Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

2005 • 4,573 citations

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

2005 • 4,165 citations

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

2005 • 3,961 citations

TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells

2006 • 3,545 citations

Interleukin-17 Family Members and Inflammation

2004 • 2,340 citations

Interleukin-23 Promotes a Distinct CD4 T Cell Activation State Characterized by the Production of Interleukin-17

2003 • 1,828 citations

IL-25 Induces IL-4, IL-5, and IL-13 and Th2-Associated Pathologies In Vivo

2001 • 1,159 citations

Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium

1999 • 943 citations

The IL-12 Family of Heterodimeric Cytokines

2003 • 889 citations

New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions

2005 • 844 citations

T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells

2001 • 743 citations

Identification of an interleukin (IL)-25–dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion

2006 • 701 citations

Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae

2005 • 598 citations

Signaling by IL‐12 and IL‐23 and the immunoregulatory roles of STAT4

2004 • 547 citations

IL-23 Compensates for the Absence of IL-12p70 and Is Essential for the IL-17 Response during Tuberculosis but Is Dispensable for Protection and Antigen-Specific IFN-γ Responses if IL-12p70 Is Available

2005 • 459 citations

Cutting Edge: Roles of Toll-Like Receptor 4 and IL-23 in IL-17 Expression in Response toKlebsiella pneumoniaeInfection

2003 • 452 citations

IL-17 Is Produced by Some Proinflammatory Th1/Th0 Cells But Not by Th2 Cells

1999 • 415 citations

Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights.

2003 • 375 citations

Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract

2006 • 372 citations

IL-17 cytokine family

2004 • 335 citations

Cutting Edge: IL-17D, a Novel Member of the IL-17 Family, Stimulates Cytokine Production and Inhibits Hemopoiesis

2002 • 317 citations

Induction of Experimental Autoimmune Encephalomyelitis in IL-12 Receptor-β2-Deficient Mice: IL-12 Responsiveness Is Not Required in the Pathogenesis of Inflammatory Demyelination in the Central Nervous System

2003 • 304 citations

Compromised Humoral and Delayed-Type Hypersensitivity Responses in IL-23-Deficient Mice

2004 • 209 citations

Stimulation of 92‐kd gelatinase (matrix metalloproteinase 9) production by interleukin‐17 in human monocyte/macrophages: A possible role in rheumatoid arthritis

2000 • 157 citations

Stimulation of 92-kd gelatinase (matrix metalloproteinase 9) production by interleukin-17 in human monocyte/macrophages: A possible role in rheumatoid arthritis

2000 • 145 citations

Molecular aspects of T-cell differentiation

2000 • 105 citations

Pulmonary Interleukin-23 Gene Delivery Increases Local T-Cell Immunity and Controls Growth ofMycobacterium tuberculosisin the Lungs

2005 • 102 citations

Involvement of TNF Receptor-Associated Factor 6 in IL-25 Receptor Signaling

2006 • 100 citations