Exon skipping by mutation of an authentic splice site ofc-kitgene inW/Wmouse

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

1987 • 1,627 citations

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

1988 • 1,390 citations

The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

1988 • 1,336 citations

Hereditary Anemias of the Mouse: A Review for Geneticists

1979 • 1,141 citations

Splicing of Messenger RNA Precursors

1987 • 919 citations

Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family-oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.

1988 • 727 citations

Specific transcription and RNA splicing defects in five cloned β-thalassaemia genes

1983 • 627 citations

Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W.

1990 • 599 citations

Fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient W/Wv mice. Evidence that cultured mast cells can give rise to both connective tissue type and mucosal mast cells.

1985 • 503 citations

Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice.

1989 • 495 citations

A role for exon sequences and splice-site proximity in splice-site selection

1986 • 494 citations

Heterogeneity of Mast Cells and Phenotypic Change Between Subpopulations

1989 • 484 citations

Functionally distinct insulin receptors generated by tissue-specific alternative splicing.

1990 • 356 citations

W mutant mice with mild or severe developmental defects contain distinct point mutations in the kinase domain of the c-kit receptor.

1990 • 349 citations

A minimal intron length but no specific internal sequence is required for splicing the large rabbit β-globin intron

1984 • 328 citations

The Dominant W ⁴² Spotting Phenotype Results from a Missense Mutation in the c- kit Receptor Kinase

1990 • 287 citations

Scanning from an independently specified branch point defines the 3′ splice site of mammalian introns

1989 • 267 citations

Tight linkage between a splicing mutation and a specific DNA haplotype in phenylketonuria

1986 • 249 citations

Unusual splice sites revealed by mutagenic inactivation of an authentic splice site of the rabbit β-globin gene

1983 • 235 citations

The chromosomal gene structure and two mRNAs for human granulocyte colony-stimulating factor.

1986 • 227 citations

Splicing of Messenger RNA Precursors

1987 • 219 citations

Splice junction mutation in some Ashkenazi Jews with Tay-Sachs disease: evidence against a single defect within this ethnic group.

1988 • 143 citations

The 5′ splice site: phylogetic evalution and variable geometry of association with U1RNA

1989 • 113 citations

A seven-base-pair deletion in an intron of the albumin gene of analbuminemic rats.

1983 • 100 citations

Haemophilia B caused by a point mutation in a donor splice junction of the human factor IX gene

1985 • 84 citations

A presumed deletion covering theWandPhloci of the mouse

1984 • 41 citations