Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family-oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

1987 • 11,429 citations

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination

1977 • 3,548 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

1985 • 2,257 citations

Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

1987 • 1,627 citations

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1

1985 • 1,590 citations

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1986 • 1,244 citations

The neu oncogene encodes an epidermal growth factor receptor-related protein

1986 • 1,131 citations

A thousand and one protein kinases

1987 • 1,066 citations

Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185

1986 • 1,020 citations

erb B-2 Is a Potent Oncogene When Overexpressed in NIH/3T3 Cells

1987 • 1,015 citations

Expression and structure of the human NGF receptor

1986 • 956 citations

Protein translocation across the endoplasmic reticulum

1984 • 825 citations

A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences

1986 • 795 citations

Multiple Mechanisms of Protein Insertion into and Across Membranes

1985 • 720 citations

Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation

1987 • 648 citations

Direct visualization of binding, aggregation, and internalization of insulin and epidermal growth factor on living fibroblastic cells

1978 • 647 citations

A new acute transforming feline retrovirus and relationship of its oncogene v-kit with the protein kinase gene family

1986 • 647 citations

Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor

1987 • 609 citations

Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src

1987 • 567 citations

Tyr ⁵²⁷ Is Phosphorylated in pp60 ^{c- src} : Implications for Regulation

1986 • 567 citations

Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors.

1987 • 567 citations

Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus

1986 • 478 citations

Activation of the pp60c-src kinase by middle T antigen binding or by dephosphorylation.

1985 • 439 citations

Cell transformation by pp60c-src mutated in the carboxy-terminal regulatory domain

1987 • 410 citations

Aligning amino acid sequences: Comparison of commonly used methods

1985 • 400 citations

The erbB gene of avian erythroblastosis virus is a member of the src gene family

1983 • 377 citations

Transforming potential of the c-fms proto-oncogene (CSF-1 receptor)

1987 • 357 citations

Two human c-onc genes are located on the long arm of chromosome 8.

1982 • 329 citations

Neuronal pp60 ^{c- src} Contains a Six-Amino Acid Insertion Relative to Its Non-Neuronal Counterpart

1987 • 313 citations

High-resolution chromosomal localization of human genes for amylase, proopiomelanocortin, somatostatin, and a DNA fragment (D3S1) by in situ hybridization.

1983 • 274 citations

A family of unusually spliced biologically active transcripts encoded by a Drosophila clock gene

1987 • 235 citations

Evidence for the Involvement of GM-CSF and FMS in the Deletion (5q) in Myeloid Disorders

1986 • 233 citations

c-erbB activation in ALV-induced erythroblastosis: novel RNA processing and promoter insertion result in expression of an amino-truncated EGF receptor

1985 • 216 citations

Affinity labeling of cAMP-dependent protein kinase with p-fluorosulfonylbenzoyl adenosine. Covalent modification of lysine 71.

1981 • 191 citations

In vivo modification of retroviral gag gene-encoded polyproteins by myristic acid

1983 • 186 citations

Nucleotide sequence of avian sarcoma virus UR2 and comparison of its transforming gene with other members of the tyrosine protein kinase oncogene family

1985 • 167 citations

Isolation and expression of cDNA clones encoding a human receptor for IgG (Fc gamma RII).

1987 • 150 citations

Evidence for Ancient Tetraploidy and Conservation of Linkage Groups in Mammalian Chromosomes

1972 • 118 citations

Localization of c-ras oncogene family on human germ-line chromosomes.

1983 • 108 citations

Proto-oncogene c-ros codes for a molecule with structural features common to those of growth factor receptors and displays tissue specific and developmentally regulated expression.

1986 • 100 citations

An insertional mutant of epidermal growth factor receptor allows dissection of diverse receptor functions.

1987 • 85 citations

The Parodi-Irgens feline sarcoma virus and simian sarcoma virus have homologous oncogenes, but in different contexts of the viral genomes

1983 • 65 citations

A new acute transforming feline retrovirus with fms homology specifies a C-terminally truncated version of the c-fms protein that is different from SM-feline sarcoma virus v-fms protein

1986 • 52 citations

Human c-fos oncogene mapped within chromosomal region 14q21----q31.

1984 • 51 citations

Activation of c-erbB in avian leukosis virus-induced erythroblastosis leads to the expression of a truncated EGF receptor kinase.

1985 • 47 citations

NOTES: Deregulation of the c-myc Oncogene in Virus-Induced Thymic Lymphomas of AKR/J Mice

1986 • 36 citations

Proto-Oncogene c-ros Codes for a Molecule with Structural Features Common to Those of Growth Factor Receptors and Displays Tissue-Specific and Developmentally Regulated Expression

1986 • 34 citations

Nucleic acid sequence and oncogenic properties of the HZ2 feline sarcoma virus v-abl insert

1987 • 33 citations

Mid-pachytene chromomere maps of human autosomes

1982 • 31 citations

Immunoglobulin-Related Structures Associated with Vertebrate Cell Surfaces

1988 • 17 citations

Human metallothionein-II processed gene is located in region p11→q21 of chromosome 4

1985 • 13 citations