Genes establishing dorsoventral pattern formation in the zebrafish embryo: the ventral specifying genes

Stages of embryonic development of the zebrafish

1995 • 11,263 citations

Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse.

1995 • 1,782 citations

The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio

1996 • 1,633 citations

Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes

1994 • 1,114 citations

HNF-3β is essential for node and notochord formation in mouse development

1994 • 985 citations

Structure of the zebrafish snail1 gene and its expression in wild-type, spadetail and no tail mutant embryos

1993 • 892 citations

Requirement for LIml in head-organizer function

1995 • 801 citations

The winged-helix transcription factor HNF-3β is required for notochord development in the mouse embryo

1994 • 786 citations

fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation.

1994 • 784 citations

Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis.

1995 • 784 citations

Induction of epidermis and inhibition of neural fate by Bmp-4

1995 • 782 citations

A common plan for dorsoventral patterning in Bilateria

1996 • 774 citations

A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse

1994 • 769 citations

Large-scale mutagenesis in the zebrafish: in search of genes controlling development in a vertebrate

1994 • 762 citations

Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity

1994 • 759 citations

A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-β family

1987 • 756 citations

Murine FGFR-1 is required for early postimplantation growth and axial organization.

1994 • 748 citations

Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus

1995 • 731 citations

Origin and organization of the zebrafish fate map

1990 • 692 citations

Developmental regulation of zebrafish MyoD in wild-type, no tail and spadetail embryos

1996 • 653 citations

Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of a vegetal dorsalizing center

1991 • 651 citations

The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo

1992 • 648 citations

Intraembryonic hematopoietic cell migration during vertebrate development.

1995 • 600 citations

Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development

1992 • 573 citations

Cell movements during epiboly and gastrulation in zebrafish

1990 • 552 citations

Fate map for the 32-cell stage ofXenopus laevis

1987 • 500 citations

Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos

1995 • 492 citations

DVR-4 (Bone Morphogenetic Protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction

1992 • 488 citations

decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo

1992 • 480 citations

Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo

1994 • 463 citations

Lithium perturbation and goosecoid expression identify a dorsal specification pathway in the pregastrula zebrafish

1993 • 458 citations

Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus.

1993 • 449 citations

A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo.

1994 • 449 citations

Expression of the zebrafish paired box gene pax[zf-b] during early neurogenesis

1991 • 443 citations

A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin

1995 • 436 citations

On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo.

1994 • 396 citations

A Genetic Linkage Map for the Zebrafish

1994 • 385 citations

Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction.

1995 • 368 citations

Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm

1993 • 365 citations

Cardiovascular development in the zebrafish I. Myocardial fate map and heart tube formation

1993 • 365 citations

Ventral mesodermal patterning in Xenopus embryos: Expression patterns and activities of BMP‐2 and BMP‐4

1995 • 344 citations

dino and mercedes, two genes regulating dorsal development in the zebrafish embryo

1996 • 325 citations

Xwnt-11: a maternally expressed Xenopus wnt gene

1993 • 308 citations

Dorsal-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation gene.

1994 • 307 citations

Expression of zebrafish goosecoid and no tail gene products in wild-type and mutant no tail embryos

1994 • 294 citations

The decapentaplegic gene is required for dorsal-ventral patterning of the Drosophila embryo.

1987 • 288 citations

Vertebrate Embryonic Induction: Mesodermal and Neural Patterning

1994 • 286 citations

An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo

1993 • 283 citations

Human BMP sequences can confer normal dorsal-ventral patterning in the Drosophila embryo.

1993 • 283 citations

Expression pattern of zebrafish pax genes suggests a role in early brain regionalization

1991 • 255 citations

Inducing factors in Xenopus early embryos

1994 • 234 citations

Regulation of Spemann organizer formation by the intracellular kinase Xgsk-3

1995 • 233 citations

Zebrafishwnt8andwnt8bshare a common activity but are involved in distinct developmental pathways

1995 • 231 citations

Localized BMP-4 Mediates Dorsal/Ventral Patterning in the Early Xenopus Embryo

1995 • 229 citations

The T genes in embryogenesis

1994 • 215 citations

The causal analysis of development in the past half century: a personal history

1992 • 214 citations

The ventral and posterior expression of the zebrafish homeobox gene eve1 is perturbed in dorsalized and mutant embryos

1993 • 196 citations

Brachyury - a gene affecting mouse gastrulation and early organogenesis

1992 • 180 citations

Synergistic principles of development: overlapping patterning systems in Xenopus mesoderm induction

1992 • 178 citations

The zebrafish epiboly mutants

1996 • 169 citations

The frog prince-ss: a molecular formula for dorsoventral patterning in Xenopus.

1993 • 167 citations

Bone morphogenetic protein 4 (BMP-4), a member of the TGF-β family, in early embryos of Xenopus laevis: analysis of mesoderm inducing activity

1991 • 167 citations

A truncated bone morphogenetic protein 4 receptor alters the fate of ventral mesoderm to dorsal mesoderm: roles of animal pole tissue in the development of ventral mesoderm.

1994 • 162 citations

Production of germ-line chimeras in zebrafish by cell transplants from genetically pigmented to albino embryos.

1992 • 150 citations

Induction of dorsal mesoderm by soluble, mature Vg1 protein

1995 • 150 citations

Cardiovascular development in the zebrafish: II. Endocardial progenitors are sequestered within the heart field

1994 • 147 citations

The transforming growth factor beta family and induction of the vertebrate mesoderm: bone morphogenetic proteins are ventral inducers.

1994 • 145 citations

Xwnt-8b: a maternally expressed Xenopus Wnt gene with a potential role in establishing the dorsoventral axis

1995 • 139 citations

The role of gsc and BMP-4 in dorsal-ventral patterning of the marginal zone in Xenopus: a loss-of-function study using antisense RNA.

1995 • 137 citations

The fub-1 mutation blocks initial myofibril formation in zebrafish muscle pioneer cells

1991 • 127 citations

Growth factors in development: the role of TGF-β related polypeptide signalling molecules in embryogenesis

1994 • 124 citations

Distribution of tissue progenitors within the shield region of the zebrafish gastrula

1995 • 112 citations

Erythropoiesis in the developing rainbow trout, Salmo gairdneri irideus: histochemical and immunochemical detection of erythropoietic organs

1983 • 97 citations

Is ventral in insects dorsal in vertebrates?

1994 • 92 citations

Drosophila short gastrulation induces an ectopic axis in Xenopus: evidence for conserved mechanisms of dorsal-ventral patterning

1995 • 76 citations

Structures Developed in Amphibians by Implantation of Living Fish Organizer

1936 • 52 citations

Dorso-ventral polarity of the zebrafish embryo is distinguishable prior to the onset of gastrulation

1994 • 39 citations

Is ventral in insects dorsal in vertebrates?

1997 • 34 citations