The frog prince-ss: a molecular formula for dorsoventral patterning in Xenopus.

Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos

1992 • 1,176 citations

Embryonic Development and Induction

1939 • 1,175 citations

Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in xenopus embryos

1991 • 1,103 citations

Expression of a xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction

1991 • 980 citations

Retinoic acid causes an anteroposterior transformation in the developing central nervous system

1989 • 885 citations

Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid

1991 • 799 citations

A maternal mRNA localized to the vegetal hemisphere in xenopus eggs codes for a growth factor related to TGF-β

1987 • 747 citations

Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of a vegetal dorsalizing center

1991 • 651 citations

Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures

1990 • 600 citations

Vital dye mapping of the gastrula and neurula of Xenopus laevis

1976 • 576 citations

Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development

1992 • 573 citations

A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos

1992 • 538 citations

The entire mesodermal mantle behaves as Spemann's organizer in dorsoanterior enhanced Xenopus laevis embryos

1988 • 521 citations

Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate

1990 • 508 citations

Injected Wnt RNA induces a complete body axis in Xenopus embryos

1991 • 501 citations

Fate map for the 32-cell stage ofXenopus laevis

1987 • 500 citations

Novel activin receptors: Distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors

1992 • 495 citations

DVR-4 (Bone Morphogenetic Protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction

1992 • 488 citations

Responses of embryonic xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm

1992 • 486 citations

Cortical rotation of the Xenopus egg: consequences for the anteroposterior pattern of embryonic dorsal development

1989 • 418 citations

MyoD expression in the forming somites is an early response to mesoderm induction in Xenopus embryos.

1989 • 374 citations

Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderminducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis

1991 • 373 citations

The LIM domain-containing homeo box gene Xlim-1 is expressed specifically in the organizer region of Xenopus gastrula embryos.

1992 • 371 citations

The Presence of Fibroblast Growth Factor in the Frog Egg: Its Role as a Natural Mesoderm Inducer

1988 • 367 citations

Identification of a retinoic acid-sensitive period during primary axis formation in Xenopus laevis.

1990 • 364 citations

Organizer-Specific Homeobox Genes in Xenopus laevis Embryos

1991 • 349 citations

Mix.1, a homeobox mRNA inducible by mesoderm inducers, is expressed mostly in the presumptive endodermal cells of Xenopus embryos

1989 • 316 citations

Early cellular interactions promote embryonic axis formation in Xenopus laevis

1984 • 291 citations

Regional specification within the mesoderm of early embryos of Xenopus laevis

1987 • 286 citations

Mesoderm induction and mesoderm-inducing factors in early amphibian development

1989 • 274 citations

Dorsalization and neural induction: properties of the organizer in Xenopus laevis.

1983 • 267 citations

Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos

1989 • 264 citations

A mRNA localized to the vegetal cortex of Xenopus oocytes encodes a protein with a nanos-like zinc finger domain

1993 • 260 citations

A homeobox-containing marker of posterior neural differentiation shows the importance of predetermination in neural induction

1987 • 250 citations

Ubiquitous MyoD transcription at the midblastula transition precedes induction-dependent MyoD expression in presumptive mesoderm of X. laevis

1991 • 248 citations

A novel, activin-inducible, blastopore lip-specific gene of Xenopus laevis contains a fork head DNA-binding domain.

1992 • 236 citations

Ectopic mesoderm formation in Xenopus embryos caused by widespread expression of a Brachyury homologue

1992 • 228 citations

Cloning of a Second Type of Activin Receptor and Functional Characterization in Xenopus Embryos

1992 • 226 citations

Retinoic acid modifies mesodermal patterning in early Xenopus embryos.

1991 • 221 citations

The biological effects of XTC-MIF: quantitative comparison with Xenopus bFGF

1990 • 220 citations

The causal analysis of development in the past half century: a personal history

1992 • 214 citations

Involvement of p21ras in Xenopus mesoderm induction

1992 • 207 citations

Differential activation of Xenopus homeo box genes by mesoderm-inducing growth factors and retinoic acid.

1990 • 199 citations

Pre-existent pattern in Xenopus animal pole cells revealed by induction with activin

1991 • 194 citations

Lithium-induced teratogenesis in frog embryos prevented by a polyphosphoinositide cycle intermediate or a diacylglycerol analog

1989 • 185 citations

Involvement of the Xenopus homeobox gene Xhox3 in pattern formation along the anterior-posterior axis

1989 • 181 citations

Mechanism of anteroposterior axis specification in vertebrates Lessons from the amphibians

1992 • 179 citations

Synergistic principles of development: overlapping patterning systems in Xenopus mesoderm induction

1992 • 178 citations

Bone morphogenetic protein 4 (BMP-4), a member of the TGF-β family, in early embryos of Xenopus laevis: analysis of mesoderm inducing activity

1991 • 167 citations

Retinoic acid perturbs the expression of Xhox.lab genes and alters mesodermal determination in Xenopus laevis.

1991 • 163 citations

Xwnt-8 modifies the character of mesoderm induced by bFGF in isolated Xenopus ectoderm.

1992 • 155 citations

Presence of activin (erythroid differentiation factor) in unfertilized eggs and blastulae of Xenopus laevis.

1991 • 151 citations

Multiple retinoid-responsive receptors in a single cell: families of retinoid "X" receptors and retinoic acid receptors in the Xenopus egg.

1992 • 147 citations

Presence of basic fibroblast growth factor in the early Xenopus embryo

1989 • 144 citations

Acquisition of developmental autonomy in the equatorial region of the Xenopus embryo

1986 • 143 citations

Developmental expression of the Xenopus int-2 (FGF-3) gene: activation by mesodermal and neural induction

1992 • 136 citations

Regulation of the fibroblast growth factor receptor in early Xenopus embryos.

1990 • 135 citations

Effect of Wnt-1 and Related Proteins on Gap Junctional Communication in Xenopus Embryos

1991 • 129 citations

Inductive effects of fibroblast growth factor and lithium ion on Xenopus blastula ectoderm

1988 • 126 citations

Identification in Xenopus of a structural homologue of the Drosophila gene Snail

1990 • 124 citations

Localized maternal mRNA related to transforming growth factor beta mRNA is concentrated in a cytokeratin-enriched fraction from Xenopus oocytes.

1988 • 123 citations

Activation of muscle genes without myogenesis by ectopic expression of MyoD in frog embryo cells

1990 • 120 citations

The timing of early developmental events in Xenopus

1985 • 114 citations

Protein kinase C isozymes have distinct roles in neural induction and competence in Xenopus

1992 • 110 citations

Dorsalization of mesoderm induction by lithium

1989 • 109 citations

The anterior extent of dorsal development of the Xenopus embryonic axis depends on the quantity of organizer in the late blastula

1990 • 102 citations

DORSALIZATION OF THE VENTRAL MARGINAL ZONE OF THE TRITURUS GASTRULA. I. AMMONIA-TREATMENT OF THE MEDIO-VENTRAL MARGINAL ZONE

1950 • 95 citations

Transient expression of XMyoD in non-somitic mesoderm of Xenopus gastrulae

1991 • 94 citations

Interaction of Wnt and activin in dorsal mesoderm induction in Xenopus

1992 • 89 citations

The Xenopus MyoD gene: an unlocalised maternal mRNA predates lineage- restricted expression in the early embryo

1990 • 85 citations

Signals from the dorsal blastopore lip region during gastrulation bias the ectoderm toward a nonepidermal pathway of differentiation in Xenopus laevis

1989 • 77 citations

Protein Kinase C and Regulation of the Local Competence of Xenopus Ectoderm

1991 • 66 citations

Spatial distribution of the capacity to initiate a secondary embryo in the 32-cell embryo ofXenopus laevis

1990 • 64 citations

Synaptic basal lamina contains a signal for synapse-specific transcription

1992 • 60 citations

Autonomous differentiation of dorsal axial structures from an animal cap cleavage stage blastomere in Xenopus

1991 • 60 citations

Nuclear translocation of fibroblast growth factor during Xenopus mesoderm induction

1991 • 59 citations

Two UV-sensitive targets in dorsoanterior specification of frog embryos

1989 • 58 citations

Induction of dorsal and ventral mesoderm by ectopically expressed Xenopus basic fibroblast growth factor

1992 • 56 citations

Dynamics of the control of body pattern in the development of Xenopus laevis. I. Timing and pattern in the development of dorsoanterior and posterior blastomere pairs, isolated at the 4-cell stage.

1985 • 52 citations

Differentiation during Cleavage in Xenopus laevis. I

1970 • 49 citations

Gastrulation and larval pattern in Xenopus after blastocoelic injection of a Xenopus-derived inducing factor: Experiments testing models for the normal organization of mesoderm

1989 • 43 citations

Potentiation by the lithium ion of morphogenetic responses to a Xenopus inducing factor

1989 • 37 citations

MyoD protein expression in Xenopus embryos closely follows a mesoderm induction-dependent amplification of MyoD transcription and is synchronous across the future somite axis

1992 • 26 citations

Over-expression of fibroblast growth factors in Xenopus embryos

1992 • 26 citations

The system specifying body position in the early development of Xenopus, and its response to early perturbations

1985 • 13 citations

Ectopic induction of dorsal mesoderm by overexpression of Xwnt-8 elevates the neural competence of Xenopus ectoderm

1992 • 12 citations