Immunolocalization of the ubiquitin-protein ligase Nedd4 in tissues expressing the epithelial Na+ channel (ENaC)

PERIODATE-LYSINE-PARAFORMALDEHYDE FIXATIVE A NEW FIXATIVE FOR IMMUNOELECTRON MICROSCOPY

1974 • 3,882 citations

Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

1994 • 1,943 citations

Degradation of CFTR by the ubiquitin-proteasome pathway

1995 • 1,285 citations

Liddle's syndrome: Heritable human hypertension caused by mutations in the β subunit of the epithelial sodium channel

1994 • 1,238 citations

Epithelial sodium channel related to proteins involved in neurodegeneration

1993 • 911 citations

WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome.

1996 • 828 citations

Hypertension caused by a truncated epithelial sodium channel γ subunit: genetic heterogeneity of Liddle syndrome

1995 • 743 citations

Identification of a set of genes with developmentally down-regulated expression in the mouse brain

1992 • 537 citations

Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome.

1996 • 397 citations

Cell-specific expression of epithelial sodium channel alpha, beta, and gamma subunits in aldosterone-responsive epithelia from the rat: localization by in situ hybridization and immunocytochemistry.

1994 • 376 citations

A de novo missense mutation of the beta subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity.

1995 • 357 citations

Improved method for obtaining 3-microns cryosections for immunocytochemistry.

1990 • 314 citations

A mutation in the epithelial sodium channel causing Liddle disease increases channel activity in the Xenopus laevis oocyte expression system.

1995 • 304 citations

Localization and regulation by steroids of the ?, ? and ? subunits of the amiloride-sensitive Na+ channel in colon, lung and kidney

1995 • 233 citations

Liddle disease caused by a missense mutation of beta subunit of the epithelial sodium channel gene.

1996 • 226 citations

Regulation of Na channels of the rat cortical collecting tubule by aldosterone.

1993 • 208 citations

Cell-specific localization of CFTR mRNA shows developmentally regulated expression in human fetal tissues

1993 • 122 citations

Molecular properties of epithelial, amiloride‐blockable Na ⁺ channels

1994 • 112 citations

rENaC is the predominant Na+ channel in the apical membrane of the rat renal inner medullary collecting duct.

1995 • 77 citations