Structural Requirements of the Glucocorticoid and Retinoic Acid Response Units in the Phosphoenolpyruvate Carboxykinase Gene Promoter

A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors

1996 • 2,183 citations

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

1996 • 1,457 citations

Transcriptional Control Signals of a Eukaryotic Protein-Coding Gene

1982 • 1,406 citations

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

1997 • 1,300 citations

Transcriptional activation: A complex puzzle with few easy pieces

1994 • 1,112 citations

TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors.

1996 • 1,095 citations

Mechanism of transcriptional activation by Sp1: Evidence for coactivators

1990 • 1,029 citations

Virus induction of human IFNβ gene expression requires the assembly of an enhanceosome

1995 • 994 citations

REGULATION OF PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP) GENE EXPRESSION

1997 • 726 citations

GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors.

1996 • 702 citations

Transcription Factor-Specific Requirements for Coactivators and Their Acetyltransferase Functions

1998 • 639 citations

The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18.

1995 • 627 citations

Many Transcription Factors Interact Synergistically with Steroid Receptors

1988 • 517 citations

Multihormonal regulation of phosphoenolpyruvate carboxykinase gene transcription. The dominant role of insulin.

1984 • 436 citations

cAMP stimulates transcription of the gene for cytosolic phosphoenolpyruvate carboxykinase in rat liver nuclei.

1982 • 410 citations

Interaction of Steroid Hormone Receptors with the Transcription Initiation Complex

1996 • 399 citations

Synergistic Activation of the Fibroblast Growth Factor 4 Enhancer by Sox2 and Oct-3 Depends on Protein-Protein Interactions Facilitated by a Specific Spatial Arrangement of Factor Binding Sites

1997 • 372 citations

Identification of a Sequence in the PEPCK Gene That Mediates a Negative Effect of Insulin on Transcription

1990 • 369 citations

Modularity in promoters and enhancers

1989 • 366 citations

The Mechanism of Transcriptional Synergy of an In Vitro Assembled Interferon-β Enhanceosome

1997 • 333 citations

Glucocorticoid receptor-cAMP response element-binding protein interaction and the response of the phosphoenolpyruvate carboxykinase gene to glucocorticoids.

1993 • 306 citations

Characterization of a complex glucocorticoid response unit in the phosphoenolpyruvate carboxykinase gene.

1990 • 299 citations

The genes of hepatic glucose metabolism.

1990 • 271 citations

The orphan receptors COUP-TF and HNF-4 serve as accessory factors required for induction of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids.

1995 • 223 citations

Cyclic AMP induction of phosphoenolpyruvate carboxykinase (GTP) gene transcription is mediated by multiple promoter elements.

1991 • 210 citations

A Rapid, Sensitive, and Inexpensive Assay for Chloramphenicol Acetyltransferase

1987 • 196 citations

HORMONE RESPONSE DOMAINS IN GENE TRANSCRIPTION

1992 • 185 citations

Identification of basal and cyclic AMP regulatory elements in the promoter of the phosphoenolpyruvate carboxykinase gene.

1988 • 169 citations

A retinoic acid response element is part of a pleiotropic domain in the phosphoenolpyruvate carboxykinase gene.

1991 • 140 citations

Location and characterization of two widely separated glucocorticoid response elements in the phosphoenolpyruvate carboxykinase gene.

1988 • 113 citations

Hepatic nuclear factor 3 is an accessory factor required for the stimulation of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids.

1996 • 101 citations

The Orphan Receptor COUP-TF Binds to a Third Glucocorticoid Accessory Factor Element within the Phosphoenolpyruvate Carboxykinase Gene Promoter

1996 • 90 citations

Activation of the phosphoenolpyruvate carboxykinase gene retinoic acid response element is dependent on a retinoic acid receptor/coregulator complex.

1992 • 88 citations

Further Characterization of the Glucocorticoid Response Unit in the Phosphoenolpyruvate Carboxykinase Gene. The Role of the Glucocorticoid Receptor-Binding Sites

1998 • 81 citations

Stereospecific alignment of the X and Y elements is required for major histocompatibility complex class II DRA promoter function.

1991 • 74 citations

Identification and Characterization of a Second Retinoic Acid Response Element in the Phosphoenolpyruvate Carboxykinase Gene Promoter

1996 • 68 citations

Identification and Characterization of Basal and Cyclic AMP Response Elements in the Promoter of the Rat Hexokinase II Gene

1996 • 68 citations

Signal transduction convergence: phorbol esters and insulin inhibit phosphoenolpyruvate carboxykinase gene transcription through the same 10-base-pair sequence.

1991 • 67 citations

Constraints on spacing between transcription factor binding sites in a simple adenovirus promoter.

1988 • 62 citations

Integration of multiple signals through a complex hormone response unit in the phosphoenolpyruvate carboxykinase gene promoter.

1994 • 51 citations

Structural constraints within a trimeric transcriptional regulatory region. Constitutive and interferon-gamma-inducible expression of the HLA-DRA gene.

1992 • 47 citations

Structural and functional analysis of the human phosphoenolpyruvate carboxykinase gene promoter

1995 • 44 citations

Vitamin A Regulates Genes Involved in Hepatic Gluconeogenesis in Mice: Phosphoenolpyruvate Carboxykinase, Fructose-1,6-bisphosphatase and 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase ,

1997 • 38 citations

Distance-dependent interactions between basal, cyclic AMP, and thyroid hormone response elements in the rat growth hormone promoter

1993 • 32 citations

Expression of a Highly Unstable and Insoluble Transcription Factor inEscherichia coli:Purification and Characterization of thefork headHomolog Hnf3α

1995 • 24 citations

Effects of Vitamin A Deficiency and Retinoic Acid Treatment on Expression of a Phosphoenolpyruvate Carboxykinase-Bovine Growth Hormone Gene in Transgenic Mice

1995 • 22 citations