Synergistic Activation of the Fibroblast Growth Factor 4 Enhancer by Sox2 and Oct-3 Depends on Protein-Protein Interactions Facilitated by a Specific Spatial Arrangement of Factor Binding Sites

A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif

1990 • 3,134 citations

A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes

1990 • 1,630 citations

A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells

1990 • 745 citations

Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3.

1995 • 744 citations

Requirement of FGF-4 for Postimplantation Mouse Development

1995 • 743 citations

Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse

1992 • 676 citations

The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.

1988 • 670 citations

FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb

1993 • 660 citations

LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected]

1991 • 627 citations

A regulatory hierarchy for cell specialization in yeast

1989 • 612 citations

An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family

1987 • 525 citations

A cooperative interaction between NF-kappa B and Sp1 is required for HIV-1 enhancer activation.

1993 • 480 citations

Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations.

1992 • 461 citations

The Oct-1 homoeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16

1989 • 434 citations

Determinants for selective RAR and TR recognition of direct repeat HREs.

1993 • 403 citations

Extra specificity from extradenticle: the partnership between HOX and PBX/EXD homeodomain proteins

1996 • 393 citations

OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins

1995 • 374 citations

Octamania: The POU factors in murine development

1991 • 373 citations

A B-cell coactivator of octamer-binding transcription factors

1995 • 301 citations

cDNA sequence of human transforming gene hst and identification of the coding sequence required for transforming activity.

1987 • 293 citations

Cloning, Functional Characterization, and Mechanism of Action of the B-Cell-Specific Transcriptional Coactivator OCA-B

1995 • 273 citations

An SRY-related gene expressed during spermatogenesis in the mouse encodes a sequence-specific DNA-binding protein.

1992 • 260 citations

Involvement of SOX proteins in lens-specific activation of crystallin genes.

1995 • 237 citations

Promoter-selective activation domains in Oct-1 and Oct-2 direct differential activation of an snRNA and mRNA promoter

1992 • 225 citations

High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors.

1995 • 224 citations

Spatial flexibility in ternary complexes between SRF and its accessory proteins.

1992 • 175 citations

LEF-1 contains an activation domain that stimulates transcription only in a specific context of factor-binding sites.

1993 • 161 citations

The hLEF/TCF-1 alpha HMG protein contains a context-dependent transcriptional activation domain that induces the TCR alpha enhancer in T cells.

1993 • 155 citations

The B cell coactivator Bob1 shows DNA sequence-dependent complex formation with Oct-1/Oct-2 factors, leading to differential promoter activation.

1996 • 138 citations

A single amino acid exchange transfers VP16-induced positive control from the Oct-1 to the Oct-2 homeo domain.

1992 • 134 citations

Influence of a steroid receptor DNA-binding domain on transcriptional regulatory functions.

1994 • 121 citations

Recognition of the surface of a homeo domain protein.

1992 • 115 citations

Interaction between a Novel F9-Specific Factor and Octamer-Binding Proteins Is Required for Cell-Type-Restricted Activity of the Fibroblast Growth Factor 4 Enhancer

1994 • 105 citations

Segments of the POU domain influence one another's DNA-binding specificity.

1992 • 99 citations

The Carboxy-Terminal Transactivation Domain of Oct-4 Acquires Cell Specificity through the POU Domain

1997 • 99 citations

Functional Interaction between the POU Domain Protein Tst-1/Oct-6 and the High-Mobility-Group Protein HMG-I/Y

1995 • 94 citations

Expression of the K-fgf proto-oncogene is controlled by 3' regulatory elements which are specific for embryonal carcinoma cells.

1990 • 93 citations

Purification of TCF-1 alpha, a T-cell-specific transcription factor that activates the T-cell receptor C alpha gene enhancer in a context-dependent manner.

1990 • 88 citations

The Oct-1 POU domain mediates interactions between Oct-1 and other POU proteins.

1992 • 84 citations

Site-specific conformational alteration of the Oct-1 POU domain-DNA complex as the basis for differential recognition by Vmw65 (VP16)

1994 • 81 citations

Expression of the K-fgf protooncogene is repressed during differentiation of F9 cells.

1989 • 59 citations

Altered DNA Recognition and Bending by Insertions in the α2 Tail of the Yeast a1/α2 Homeodomain Heterodimer

1995 • 48 citations

Stringent integrity requirements for bothtrans-activation and DNA-binding in atrans-activator, Oct3

1991 • 38 citations

Differential Control of Transcription by Homologous Homeodomain Coregulators†

1996 • 29 citations