Physiological and Clinical Aspects of Vitamin A and Its Metabolites

Harrison's Principles of Internal Medicine.

1988 • 11,687 citations

The Pharmacological Basis of Therapeutics

1976 • 8,675 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia

1988 • 2,380 citations

A human retinoic acid receptor which belongs to the family of nuclear receptors

1987 • 2,245 citations

Identification of a receptor for the morphogen retinoic acid

1987 • 2,007 citations

Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid.

1980 • 1,997 citations

TISSUE CHANGES FOLLOWING DEPRIVATION OF FAT-SOLUBLE A VITAMIN

1925 • 1,630 citations

Nuclear receptor that identifies a novel retinoic acid response pathway

1990 • 1,529 citations

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

1992 • 1,514 citations

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

1991 • 1,463 citations

The induction of differentiation in teratocarcinoma stem cells by retinoic acid

1978 • 1,459 citations

Prevention of Second Primary Tumors with Isotretinoin in Squamous-Cell Carcinoma of the Head and Neck

1990 • 1,375 citations

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1991 • 1,371 citations

Differentiation Therapy of Acute Promyelocytic Leukemia with Tretinoin (All-trans-Retinoic Acid)

1991 • 1,298 citations

RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1991 • 1,241 citations

All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results [see comments]

1990 • 1,224 citations

Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.

1992 • 1,200 citations

The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression

1987 • 1,180 citations

Effects of vitamin A and its analogs (retinoids) on normal and neoplastic cells

1980 • 1,094 citations

Identification of a second human retinoic acid receptor

1988 • 1,049 citations

Prevention of chemical carcinogenesis by vitamin A and its synthetic analogs (retinoids).

1976 • 993 citations

Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors

1992 • 966 citations

Identification and spatial distribution of retinoids in the developing chick limb bud

1987 • 964 citations

Determinants of target gene specificity for steroid/thyroid hormone receptors

1989 • 954 citations

Retinol-binding protein: the transport protein for vitamin A in human plasma

1968 • 892 citations

Retinoic acid causes an anteroposterior transformation in the developing central nervous system

1989 • 885 citations

13-cis-Retinoic Acid in the Treatment of Oral Leukoplakia

1986 • 825 citations

Cloning of murine α and β retinoic acid receptors and a novel receptor γ predominantly expressed in skin

1989 • 804 citations

Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells.

1982 • 791 citations

The Function and Mechanism of Promoters of Carcinogenesis

1973 • 759 citations

A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells

1990 • 745 citations

Cancer Research: Some Forward Steps

1965 • 733 citations

Cellular Biology and Biochemistry of the Retinoids

1984 • 730 citations

A third human retinoic acid receptor, hRAR-gamma.

1989 • 686 citations

Control of muscle and neuronal differentiation in a cultured embryonal carcinoma cell line

1982 • 674 citations

Local application of retinoic acid to the limb bond mimics the action of the polarizing region

1982 • 669 citations

Harrison's Principles of Internal Medicine 16th ed

2005 • 651 citations

Molecular Analysis of Acute Promyelocytic Leukemia Breakpoint Cluster Region on Chromosome 17

1990 • 650 citations

Transport and Storage of Vitamin A

1990 • 618 citations

A new retinoic acid receptor identified from a hepatocellular carcinoma

1988 • 613 citations

Activators and targets

1990 • 582 citations

Terminal differentiation of human promyelocytic leukemic cells in primary culture in response to retinoic acid

1981 • 566 citations

Diet and cancer

1979 • 555 citations

Perisinusoidal Stellate Cells (Fat-Storing Cells, Interstitial Cells, Lipocytes), Their Related Structure in and around the Liver Sinusoids, and Vitamin A-Storing Cells in Extrahepatic Organs

1980 • 532 citations

The phorbol ester receptor: a phospholipid-regulated protein kinase

1985 • 522 citations

Terminal differentiation of cultured human epidermal cells

1977 • 521 citations

Prolonged Remissions of Cystic and Conglobate Acne with 13-cis-Retinoic Acid

1979 • 518 citations

Induction of the polyamine-biosynthetic enzymes in mouse epidermis by tumor-promoting agents.

1975 • 504 citations

DIETARY VITAMIN A AND RISK OF CANCER IN THE WESTERN ELECTRIC STUDY

1981 • 489 citations

H-2RIIBP (RXR beta) heterodimerization provides a mechanism for combinatorial diversity in the regulation of retinoic acid and thyroid hormone responsive genes.

1992 • 480 citations

Vitamin A and pattern formation in the regenerating limb

1982 • 463 citations

THE BIOLOGICAL FUNCTION OF VITAMIN A ACID

1960 • 453 citations

The effects of diseases of the liver, thyroid, and kidneys on the transport of vitamin A in human plasma

1971 • 452 citations

RXR alpha, a promiscuous partner of retinoic acid and thyroid hormone receptors.

1992 • 446 citations

Protein kinase C as the receptor for the phorbol ester tumor promoters: sixth Rhoads memorial award lecture.

1988 • 430 citations

Lipoprotein structure and metabolism.

1976 • 429 citations

Tumor Promoters and the Mechanism of Tumor Promotion

1980 • 415 citations

Retinoids, homeoboxes, and growth factors: Toward molecular models for limb development

1991 • 410 citations

Dietary vitamin a and human lung cancer

1975 • 397 citations

Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid.

1991 • 395 citations

Lipoprotein binding to canine hepatic membranes. Metabolically distinct apo-E and apo-B,E receptors.

1981 • 391 citations

Differentially expressed isoforms of the mouse retinoic acid receptor beta generated by usage of two promoters and alternative splicing.

1991 • 390 citations

13-cis-Retinoic Acid and Interferon -2a: Effective Combination. Therapy for Advanced Squamous Cell Carcinoma of the Skin

1992 • 389 citations

THE NECESSITY OF CERTAIN LIPINS IN THE DIET DURING GROWTH

1913 • 386 citations

FAT-SOLUBLE VITAMINS

1934 • 377 citations

BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner

1991 • 375 citations

The Amino Acid Sequence of Human Plasma Prealbumin

1974 • 368 citations

Retinoids as preventive and therapeutic anticancer agents (Part I).

1987 • 361 citations

Two amino acids within the knuckle of the first zinc finger specify DNA response element activation by the glucocorticoid receptor

1989 • 358 citations

Experimental cancer of the lung.Inhibition by vitamin A of the induction of tracheobronchial squamous metaplasia and squamous cell tumors

1967 • 357 citations

THE INDUCTION OF ORNITHINE DECARBOXYLASE AS AN EARLY, POSSIBLY OBLIGATORY EVENT IN MOUSE SKIN CARCINOGENESIS

1976 • 353 citations

The intestinal absorption and metabolism of vitamin A and beta-carotene in man.

1966 • 351 citations

The enzymatic cleavage of beta-carotene into vitamin A by soluble enzymes of rat liver and intestine.

1965 • 342 citations

Regulation of Retinol-binding Protein Metabolism by Vitamin A Status in the Rat

1972 • 335 citations

Commitment and activation at pol II promoters: A tail of protein-protein interactions

1990 • 332 citations

A retinoic acid-responsive element is present in the 5' flanking region of the laminin B1 gene.

1989 • 314 citations

Murine isoforms of retinoic acid receptor gamma with specific patterns of expression.

1990 • 304 citations

The Role of Croton Oil Applications, Associated with a Single Painting of a Carcinogen, in Tumour Induction of the Mouse's Skin

1947 • 298 citations

Tumor-promoting Agents in Two-stage Carcinogenesis1

2015 • 296 citations

PLASMA RETINOL‐BINDING PROTEIN*

1980 • 280 citations

LOW SERUM-VITAMIN-A AND SUBSEQUENT RISK OF CANCER

1980 • 270 citations

Intestinal lipoprotein metabolism

1981 • 270 citations

Plasma Retinol-Binding Protein

1984 • 270 citations

Biosynthesis of Vitamin A with Rat Intestinal Enzymes

1965 • 267 citations

Serum vitamin levels and the risk of cancer of specific sites in men of Japanese ancestry in Hawaii.

1985 • 256 citations

13- cis -Retinoic Acid: Inhibition of Bladder Carcinogenesis in the Rat

1977 • 256 citations

Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locus.

1991 • 253 citations

Isolation of 3,4-didehydroretinoic acid, a novel morphogenetic signal in the chick wing bud

1990 • 252 citations

Retinoids: New Trends in Research and Therapy

1986 • 252 citations

The concentration of retinoic acid determines the differentiated cell types formed by a teratocarcinoma cell line

1983 • 250 citations

The Retinoids

1987 • 250 citations

Induction of the polyamine-biosynthetic enzymes in mouse epidermis and their specificity for tumor promotion.

1975 • 244 citations

Retinoic acid induces polarizing activity but is unlikely to be a morphogen in the chick limb bud

1991 • 242 citations

A speculative review; the probable nature of promoting action and its significance in the understanding of the mechanism of carcinogenesis.

1954 • 235 citations

Retinoids — Advances in Basic Research and Therapy

1982 • 234 citations

Retinoic acid. Inhibition of the clonal growth of human myeloid leukemia cells.

1982 • 224 citations

Vitamin A and carotene

1930 • 223 citations

Vitamin A and Lung Cancer<xref ref-type="fn" rid="FN2">2</xref>

1979 • 222 citations

Conversion by retinoic acid of anterior cells into ZPA cells in the chick wing bud

1991 • 218 citations

Characteristics of a Vitamin A-transporting Protein Complex Occurring in Human Serum

1971 • 218 citations

Multiple cell type-specific proteins differentially regulate target sequence recognition by the α retinoic acid receptor

1990 • 211 citations

Negative cooperativity in the binding of thyroxine to human serum prealbumin

1975 • 198 citations

Characterization of the sinusoidal transport process responsible for uptake of chylomicrons by the liver.

1978 • 197 citations

Effects of retinoic acid on the immune system: Stimulation of T killer cell induction

1978 • 192 citations

In vivo uptake of chylomicron [3H]retinyl ester by rat liver: evidence for retinol transfer from parenchymal to nonparenchymal cells.

1982 • 190 citations

Retinoic acid response element in the human alcohol dehydrogenase gene ADH3: implications for regulation of retinoic acid synthesis.

1991 • 189 citations

Physiology of the natural polyamines putrescine, spermidine and spermine.

1975 • 188 citations

An electron microscopic study of metaplasia of the rat tracheal epithelium in vitamin A deficiency.

1971 • 188 citations

Expression of REX-1, a gene containing zinc finger motifs, is rapidly reduced by retinoic acid in F9 teratocarcinoma cells.

1989 • 186 citations

Serum Vitamin A (Retinol) and Cancer Incidence in Evans County, Georgia

1981 • 184 citations

Chemistry and Biology of Synthetic Retinoids

2018 • 182 citations

Inhibitory Effects of Retinoic Acid or Retinyl Acetate on the Growth of Untransformed, Transformed, and Tumor Cells In Vitro 2

1977 • 180 citations

DIETARY VITAMIN A, CAROTENE, VITAMIN C AND RISK OF LUNG CANCER IN HAWAII

1984 • 180 citations

An early effect of retinoic acid: cloning of an mRNA (Era-1) exhibiting rapid and protein synthesis-independent induction during teratocarcinoma stem cell differentiation.

1988 • 176 citations

Studies on the Protein-Protein and Protein-Ligand Interactions Involved in Retinol Transport in Plasma

1970 • 169 citations

Retinoids and cancer

1979 • 168 citations

EPITHELIAL REPAIR IN RECOVERY FROM VITAMIN A DEFICIENCY

1933 • 165 citations

Identification of a novel isoform of the retinoic acid receptor gamma expressed in the mouse embryo.

1990 • 162 citations

Retinyl acetate inhibits mammary carcinogenesis induced by N-methyl-N-nitrosourea

1977 • 159 citations

TREATMENT OF LAMELLAR ICHTHYOSIS AND OTHER KERATINISING DERMATOSES WITH AN ORAL SYNTHETIC RETINOID

1976 • 158 citations

Intestinal fat digestion, absorption, and transport A review

1980 • 158 citations

Activity of vitamin A analogues in cell cultures of mouse epidermis and organ cultures of hamster trachea

1975 • 156 citations

Histogenesis of Squamous Metaplasia in the Hamster Tracheal Epithelium Caused by Vitamin A Deficiency or Benzo[&lt;italic&gt;a&lt;/italic&gt;]pyrene-Ferric Oxide

1972 • 156 citations

Retinoic acid metabolism by a system reconstituted with cytochrome P-450

1984 • 154 citations

All-trans-retinoic acid: measurement of reference values in human serum by high performance liquid chromatography

1982 • 153 citations

Identification of mouse liver aldehyde dehydrogenases that catalyze the oxidation of retinaldehyde to retinoic acid

1991 • 152 citations

The Interaction of Human Plasma Retinol-binding Protein with Prealbumin

1973 • 147 citations

Intestinal absorption of vitamins A, E, D, and K.

1981 • 147 citations

The effects of 13-cis-retinoic acid and beta-carotene on cellular immunity in humans

1991 • 146 citations

Studies on the Interaction Between Prealbumin, Retinol-binding Protein, and Vitamin A

1971 • 146 citations

Identification of human liver aldehyde dehydrogenases that catalyze the oxidation of aldophosphamide and retinaldehyde

1992 • 145 citations

Retinoids and Cancer

1984 • 143 citations

Ornithine decarboxylase activity in the rat and human colon.

1984 • 142 citations

Zur Kenntnis des Vitamins-A aus Fischtranen

1931 • 141 citations

A retinoic acid response element is part of a pleiotropic domain in the phosphoenolpyruvate carboxykinase gene.

1991 • 140 citations

Biochemical treatment of precancerous oral lesions: The effectiveness of various analogues of retinoic acid

1978 • 138 citations

Control mechanisms in cancer

1976 • 138 citations

beta-carotene intestinal absorption: bile, fatty acid, pH, and flow rate effects on transport.

1978 • 138 citations

Influence of vitamin A on immunological response.

1972 • 136 citations

Treatment of Advanced Squamous Cell Carcinoma of the Skin with Isotretinoin

1987 • 134 citations

Ligand specificities of recombinant retinoic acid receptors RAR α and RAR β

1990 • 131 citations

In vitro metabolism of retinoic acid in hamster intestine and liver.

1979 • 129 citations

Metabolism of all-trans-retinoic acid in hamster liver microsomes: Oxidation of 4-hydroxy- to 4-keto-retinoic acid

1980 • 127 citations

Studies on the substrate specificity of a carboxyl ester hydrolase from human pancreatic juice. I. Action on carboxyl esters, glycerides and phospholipids

1980 • 126 citations

An X-ray study of the subunit structure of prealbumin

1971 • 126 citations

Quantification of retinoic acid by gas-liquid chromatography-mass spectrometry: total versus all-trans-retinoic acid in human plasma.

1985 • 126 citations

Isolation and identification of 4-hydroxy- and 4-oxoretinoic acid. In vitro metabolites of all-trans-retinoic acid in hamster trachea and liver

1979 • 126 citations

Biosynthesis, Absorption, and Hepatic Metabolism of Retinol

1984 • 121 citations

Studies on the Intestinal Absorption of Radioactive β-Carotene and Vitamin A in Man: Conversion of β-carotene into vitamin A

1967 • 118 citations

The Effects of Chylomicron Vitamin A on the Metabolism of Retinol-binding Protein in the Rat

1973 • 117 citations

Characterization of DNA binding and retinoic acid binding properties of retinoic acid receptor.

1991 • 114 citations

Retinol is essential for growth of activated human B cells.

1990 • 112 citations

Polyamine and differentiation: induction of ornithine decarboxylase by parathyroid hormone is a good marker of differentiated chondrocytes.

1980 • 112 citations

α and β-Retinyl acetate reverse metaplasias of vitamin A deficiency in hamster trachea in organ culture

1974 • 111 citations

Retinoyl β-glucuronide: an endogenous compound of human blood

1986 • 101 citations

Metabolism of the Retina

1964 • 100 citations

Reversal of methylcholanthrene-induced changes in mouse prostates in vitro by retinoic acid and its analogues

1976 • 99 citations

Mode of Action of Adjuvants: Retinol and other Lysosome-Labilizing Agents As Adjuvants

1970 • 98 citations

TOPICAL VITAMIN-A-ACID THERAPY FOR CUTANEOUS METASTATIC MELANOMA

1980 • 98 citations

Activity of isotretinoin against squamous cell cancers and preneoplastic lesions.

1982 • 97 citations

The effect of localized injection of adjuvant material on the draining lymph node. I. Histology.

1970 • 93 citations

Antagonism between Retinoic Acid Receptors

1991 • 91 citations

Pathways of absorption of retinal and retinoic acid in the rat

1968 • 91 citations

Experimental Cancer of the Lung

1962 • 89 citations

Effect of avitaminosis A and hypervitaminosis A on urinary bladder carcinogenicity of N-(4-(5-Nitro-2-furyl)-2-thiazolyl)formamide.

1976 • 88 citations

Vitamin A1 intestinal absorption in vivo: influence of luminal factors on transport.

1977 • 86 citations

Stimulation of Immune Response in Lung Cancer Patients by Vitamin A Therapy

1977 • 86 citations

Preadipocytes possess cellular retinoid binding proteins and their differentiation is inhibited by retinoids

1980 • 86 citations

We have a morphogen!

1987 • 85 citations

Unusual properties of retinyl palmitate hydrolase activity in rat liver.

1979 • 85 citations

Chondrogenesis and cell proliferation in limb bud cell cultures treated with cytosine arabinoside and vitamin A

1978 • 84 citations

DIETARY VITAMIN A AND LUNG CANCER RISK: AN ANALYSIS BY HISTOLOGIC SUBTYPES

1984 • 84 citations

Nutrition and Cancer Prevention. Investigating the Role of Micronutrients

1990 • 82 citations

THE INFLUENCE OF BUTTER-FAT ON GROWTH

1914 • 77 citations

In vitro and in vivo metabolism of all-trans- and 13-cis-retinoic acid in hamsters. Identification of 13-cis-4-oxoretinoic acid.

1980 • 75 citations

The Enzymatic Reduction of Retinal to Retinol in Rat Intestine

1968 • 75 citations

Purification and properties of carotene 15,15′-dioxygenase of rabbit intestine

1972 • 74 citations

International studies of the efficacy of etretinate in the treatment of psoriasis

1982 • 72 citations

Regulation of growth and differentiated function in eukaryote cells

1975 • 72 citations

Nutrition and cancer prevention: investigating the role of micronutrients.

1989 • 71 citations

13-Cis-retinoic acid: Pharmacology, toxicology, and clinical applications for the prevention and treatment of human cancer

1985 • 70 citations

Retinoids and the Immune System: Immunostimulation by Vitamin A

1984 • 69 citations

STRUCTURAL AND FUNCTIONAL STUDIES OF VITAMIN A‐BINDING PROTEINS*

1981 • 69 citations

Experimental Lung Cancer Carcinogenesis and Bioassays

1976 • 69 citations

Stimulation of interleukin 1 and 3 production by retinoic acid in vitro

1985 • 68 citations

Squamous Metaplasia in Organ Cultures of Vitamin A-Deficient Hamster Trachea: Cytokinetic and Ultrastructural Alterations&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;&lt;xref ref-type="fn" rid="FN3"&gt;3&lt;/xref&gt;

1982 • 67 citations

Altered proteoglycan metabolism in mouse limb mesenchyme cell cultures treated with vitamin A

1978 • 64 citations

Effect of retinol status on retinol-binding protein biosynthesis rate and translatable messenger RNA level in rat liver.

1982 • 64 citations

Retinoic acid-induced down-regulation of the interleukin-2 promoter via cis-regulatory sequences containing an octamer motif.

1991 • 63 citations

Über die Ester und Äther des synthetischen Vitamins A

1949 • 62 citations

Sensitivity of cultured human osteosarcoma and chondrosarcoma cells to retinoic acid.

1982 • 61 citations

Effect of Retinoids on Precancerous Lesions of Oral Mucosa

1981 • 59 citations

Macromolecular and cell cycle effects of different classes of agents inducing the maturation of human myeloblastic leukemia (ML-1) cells.

1984 • 59 citations

Retinoic acid: Biochemistry and metabolism

1986 • 59 citations

Hypovitaminosis-A in the mouse prostate gland cultured in chemically defined medium

1962 • 57 citations

Treatment of advanced squamous cell carcinoma of the head and neck with isotretinoin: a phase II randomized trial

1988 • 55 citations

Antagonism between retinoic acid receptors.

1991 • 55 citations

Effect of delay in administration of 13-cis-retinoic acid on the inhibition of urinary bladder carcinogenesis in the rat.

1979 • 54 citations

Retinoic acid upregulates interleukin-2 receptors on activated human thymocytes

1988 • 54 citations

Inhibition of adipose conversion in 3T3‐L2 cells by retinoic acid

1980 • 54 citations

Biosynthesis of retinoic acid by intestinal enzymes of the rat

1967 • 53 citations

Inhibition of both stage I and stage II mouse skin tumour promotion by retinoic acid and the dependence of inhibition of tumor promotion on the duration of retinoic acid treatment.

1987 • 53 citations

Chemoprevention clinical trials

1992 • 52 citations

Diet and Chemoprevention in NCI's Research Strategy to Achieve National Cancer Control Objectives

1986 • 50 citations

Effect of retinoic acid and 4-hydroxytamoxifen on human breast cancer cell lines

1984 • 48 citations

The biochemistry of preneoplasia in mouse skin.

1976 • 47 citations

Beriberi and other Food-deficiency Diseases in Newfoundland and Labrador

1930 • 45 citations

The Storage Form of Vitamin A in Rat Liver Cells

1983 • 40 citations

Correlation between precancerous bronchial metaplasia and cigarette consumption, and preliminary results of retinoid treatment.

1982 • 39 citations

Nasopharyngeal Carcinoma. II. Ultrastructure of Normal Mucosa, Tumor Biopsies, and Subsequent Epithelial Growth &lt;italic&gt;In Vitro&lt;/italic&gt;&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;

1972 • 39 citations

Vitamin A and the susceptibility of respiratory tract tissues to carcinogenic insult.

1979 • 38 citations

The luxus vitamins—A and B

1981 • 38 citations

Control of cell differentiation during proliferation — II. Myeloid differentiation and cell cycle arrest of HL-60 promyelocytes preceded by nuclear structural changes

1985 • 37 citations

Adjuvant effect of vitamin A palmitate and analogs on cell-mediated immunity.

1981 • 36 citations

Progress in diseases of the skin

1981 • 36 citations

The Effect of Vitamin A on Cellular Differentiation and Mucous Glycoprotein Synthesis in Long-Term Rat Tracheal Organ Cultures

1979 • 36 citations

From gradients to axes, from morphogenesis to differentiation

1990 • 36 citations

Treatment of basal cell carcinoma with 13-cis-retinoic acid.

1984 • 35 citations

Immunological aspects of retinoids in humans

1984 • 34 citations

Histogenesis of squamous metaplasia and squamous cell carcinoma of the respiratory epithelium in an animal model.

1973 • 34 citations

Cellular uptake and localization of fluorescent derivatives of phorbol ester tumor promoters

1985 • 34 citations

Restoration by cyclic AMP of the differentiated phenotype of chondrocytes from de-differentiated cells pretreated with retinoids

1982 • 34 citations

Augmentation of Human Thymocyte Proliferative Responses by Retinoic Acid

1981 • 34 citations

Immunostimulation by Retinoic Acid

1985 • 33 citations

Effects of 13-CIS retinoids on premalignant and malignant cells of lung origin.

1982 • 33 citations

Effect of three retinoids on tracheal carcinogenesis with N-methyl-N-nitrosourea in hamsters.

1981 • 33 citations

Cell populations in the hamster tracheal epithelium in relation to vitamin A status.

1974 • 32 citations

The effects of a novel potent oral retinoid (Ro13-6298) in the treatment of multiple solar keratoses and squamous cell epithelioma

1983 • 32 citations

Expression of red cell membrane proteins in erythroid precursor cells

1980 • 31 citations

Control of cell differentiation during proliferation

1983 • 30 citations

Immunohistochemical localization of p53 protein in malignant hemangioendothelioma.

1994 • 30 citations

Cutaneous Neoplasia and Etretinate

1984 • 30 citations

Biosynthesis of plasma retinol-binding protein in liver as a larger molecular weight precursor.

1981 • 29 citations

Synthese des Perhydro-vitamins-A

1933 • 29 citations

Effects of retinoids on growth and dissemination of malignant tumours: Immunological considerations

1985 • 28 citations

Intestinal Absorption of Vitamin A in the Normal Rat

1940 • 24 citations

Therapy and Prevention of Skin Cancer

2015 • 22 citations

THE EFFECT OF RADIATION WITH THE MERCURY-VAPOUR QUARTZ LAMP ON THE GROWTH OF RATS FED ON A DIET DEFICIENT IN VITAMIN A.

1922 • 20 citations

N-Nitrosodiethylamine-induced nodule-like alveolar lesion and its prevention by a retinoid in BALB/c mouse mammary glands in the whole organ in culture

1982 • 18 citations

Effects of retinoic acid versus dimethyl sulfoxide on Friend erythroleukemia cell growth. II. Induction of quiescent, nonproliferating cells.

1984 • 18 citations

Decreased Resistance of C3H/HeHa Mice to C3HBA Tumor Transplants: Increased Resistance Due to Supplemental Vitamin A<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1981 • 17 citations

Action of retinoic acid on the diacylglycerol-induced ornithine decarboxylase activity, reduction in EGF binding and protein kinase C activation in rat tracheal epithelial 2C5 cells

1986 • 16 citations

Aromatic Retinoid in the Treatment of Multiple Superficial Basal Cell Carcinoma, Arsenic Keratosis and Kerato-Acanthoma

1981 • 15 citations

The alleged contamination of carotene by vitamin A

1930 • 14 citations

Inhibition of phorbol ester-caused synthesis of mouse epidermal ornithine decarboxylase by retinoic acid

1985 • 13 citations

THE RELATION BETWEEN THE GROWTH-PROMOTING AND ANTI-RACHITIC FUNCTIONS OF CERTAIN SUBSTANCES.

1923 • 13 citations

Retinoids in Oncology1

2015 • 12 citations

Retinoids in oncology.

1985 • 12 citations

Trial of an aromatic retinoid in patients with solid tumours

1982 • 11 citations

Surface Morphology of Tracheal Epithelium in Vitamin A Deficiency and Reversal

1974 • 11 citations

Dose and schedule of oral retinoic acid and indomethacin needed to effectively inhibit phorbol ester-induced epidermal ornithine decarboxylase activity

1985 • 10 citations

all‐trans‐Retinoic acid inhibits the appearance of two phorbol ester‐induced ornithine decarboxylase mRNAs in mouse epidermis

1986 • 9 citations

Phase II trial of 13-CIS-retinoic acid in metastatic breast cancer and other malignancies

1981 • 9 citations

Lung cancer chemoprevention: facts and hopes

1991 • 8 citations

Inhibition of transplanted carcinomas in mice by retinoids but not by vitamin C.

1983 • 8 citations

Etretinat (Ro 10–9359, Tigason) + CCNU (1-(2-chloroathyl)-3-cyclohexyl-1-nitrosourea) + Bleomycin versus CCNU + Bleomycin in der Behandlung des fortgeschrittenen Plattenepithel-Karzinoms des Bronchus (AIO-Studie BS1/78)

1983 • 6 citations

LYSOGENICITY AND PROPHAGE TYPE OF THE STRAINS OF VIBRIO CHOLERAE 0-1 ISOLATED MAINLY FROM THE NATURAL ENVIRONMENT

1984 • 5 citations

Elucidation of the structure of vitamin A2 by total synthesis.

1951 • 4 citations

Retinoid-binding proteins in embryonal carcinoma cells

1990 • 3 citations

Two different molecular pathways of immunomodulation by retinoids and carotenoids.

1989 • 1 citations

Problems and Solutions

1968 • 1 citations

Deleted Work

1955 • 0 citations