Dark matter in the genome: evidence of widespread transcription detected by microarray tiling experiments

Initial sequencing and analysis of the human genome

2001 • 23,520 citations

The Sequence of the Human Genome

2001 • 13,500 citations

Finishing the euchromatic sequence of the human genome

2004 • 4,741 citations

Prediction of complete gene structures in human genomic DNA

1997 • 4,041 citations

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs

2002 • 1,612 citations

Unbiased Mapping of Transcription Factor Binding Sites along Human Chromosomes 21 and 22 Points to Widespread Regulation of Noncoding RNAs

2004 • 1,079 citations

Genome-wide expression monitoring in Saccharomyces cerevisiae

1997 • 990 citations

Empirical Analysis of Transcriptional Activity in the Arabidopsis Genome

2003 • 906 citations

Complete sequencing and characterization of 21,243 full-length human cDNAs

2003 • 888 citations

Large-Scale Transcriptional Activity in Chromosomes 21 and 22

2002 • 839 citations

Functional annotation of a full-length mouse cDNA collection

2001 • 663 citations

Widespread occurrence of antisense transcription in the human genome

2003 • 655 citations

Using the transcriptome to annotate the genome

2002 • 637 citations

An Expanding Universe of Noncoding RNAs

2002 • 631 citations

Intergenic transcription is required to repress the Saccharomyces cerevisiae SER3 gene

2004 • 585 citations

Challenging the dogma: the hidden layer of non‐protein‐coding RNAs in complex organisms

2003 • 567 citations

Large-scale analysis of the yeast genome by transposon tagging and gene disruption

1999 • 536 citations

Novel RNAs Identified From an In-Depth Analysis of the Transcriptome of Human Chromosomes 21 and 22

2004 • 529 citations

Experimental annotation of the human genome using microarray technology

2001 • 446 citations

ANTISENSE RNA CONTROL IN BACTERIA, PHAGES, AND PLASMIDS

1994 • 440 citations

An expressed pseudogene regulates the messenger-RNA stability of its homologous coding gene

2003 • 401 citations

Direct Allelic Variation Scanning of the Yeast Genome

1998 • 387 citations

RNA expression analysis using a 30 base pair resolution Escherichia coli genome array

2000 • 354 citations

Over 20% of human transcripts might form sense-antisense pairs

2004 • 326 citations

The transcriptional activity of human Chromosome 22

2003 • 293 citations

A Gene Expression Map for the Euchromatic Genome of Drosophila melanogaster

2004 • 291 citations

The Mammalian Gene Collection

1999 • 277 citations

Antisense Transcripts With FANTOM2 Clone Set and Their Implications for Gene Regulation

2003 • 254 citations

Numerous potentially functional but non-genic conserved sequences on human chromosome 21

2002 • 243 citations

Antisense transcripts in the human genome

2002 • 242 citations

Large-scale identification of secreted and membrane-associated gene products using DNA microarrays

2000 • 240 citations

Molecular Fossils in the Human Genome: Identification and Analysis of the Pseudogenes in Chromosomes 21 and 22

2002 • 195 citations

Identification of 51 Novel Exons of the Usher Syndrome Type 2A (USH2A) Gene That Encode Multiple Conserved Functional Domains and That Are Mutated in Patients with Usher Syndrome Type II

2004 • 189 citations

Targeting a Complex Transcriptome: The Construction of the Mouse Full-Length cDNA Encyclopedia

2003 • 175 citations

The contribution of 700,000 ORF sequence tags to the definition of the human transcriptome

2001 • 142 citations

The brave new world of RNA

2002 • 136 citations

An integrated gene annotation and transcriptional profiling approach towards the full gene content of the Drosophila genome

2003 • 130 citations

Antisense transcripts with rice full-length cDNAs

2003 • 129 citations

Defining Genes in the Genomics Era

2003 • 126 citations

Untitled

2004 • 101 citations

Optimization of oligonucleotide arrays and RNA amplification protocols for analysis of transcript structure and alternative splicing

2003 • 85 citations

Most of the Human Genome Is Transcribed

2001 • 66 citations

Is "Junk" DNA Mostly Intron DNA?

2000 • 64 citations

Mining the human genome using microarrays of open reading frames

2000 • 49 citations

Evidence that functional transcription units cover at least half of the human genome

2004 • 38 citations