Cloning and sequencing of the bovine flavocytochrome b subunit proteins, gp91-phox and p22-phox: comparison with other known flavocytochrome b sequences

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Current protocols in molecular biology

1988 • 4,543 citations

Prediction of the occurrence of the ADP-binding βαβ-fold in proteins, using an amino acid sequence fingerprint

1986 • 1,172 citations

Cloning the gene for an inherited human disorder—chronic granulomatous disease—on the basis of its chromosomal location

1986 • 839 citations

The biochemical basis of the NADPH oxidase of phagocytes

1993 • 631 citations

The respiratory burst oxidase.

1994 • 608 citations

Assembly of the phagocyte NADPH oxidase: molecular interaction of oxidase proteins

1996 • 534 citations

Purified cytochrome b from human granulocyte plasma membrane is comprised of two polypeptides with relative molecular weights of 91,000 and 22,000.

1987 • 459 citations

Two cytosolic components of the human neutrophil respiratory burst oxidase translocate to the plasma membrane during cell activation.

1990 • 435 citations

Cytochrome b ₅₅₈ : the Flavin-Binding Component of the Phagocyte NADPH Oxidase

1992 • 384 citations

Neutrophil nicotinamide adenine dinucleotide phosphate oxidase assembly. Translocation of p47-phox and p67-phox requires interaction between p47-phox and cytochrome b558.

1991 • 379 citations

Cytochrome b-245 is a flavocytochrome containing FAD and the NADPH-binding site of the microbicidal oxidase of phagocytes

1992 • 351 citations

Human neutrophil cytochrome b light chain (p22-phox). Gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease.

1990 • 337 citations

Primary structure and unique expression of the 22-kilodalton light chain of human neutrophil cytochrome b.

1988 • 317 citations

Translocation of Rac correlates with NADPH oxidase activation. Evidence for equimolar translocation of oxidase components.

1993 • 316 citations

p40phox, a third cytosolic component of the activation complex of the NADPH oxidase to contain src homology 3 domains

1993 • 295 citations

The X-linked chronic granulomatous disease gene codes for the β-chain of cytochrome b−245

1987 • 292 citations

The electron transport chain of the microbicidal oxidase of phagocytic cells and its involvement in the molecular pathology of chronic granulomatous disease.

1989 • 286 citations

Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets.

1994 • 285 citations

Association of a Ras-related protein with cytochrome b of human neutrophils

1989 • 248 citations

Intramembrane Bis-Heme Motif for Transmembrane Electron Transport Conserved in a Yeast Iron Reductase and the Human NADPH Oxidase

1996 • 209 citations

Assembly and Activation of the Phagocyte NADPH Oxidase

1996 • 184 citations

Activation of neutrophil leukocytes: chemoattractant receptors and respiratory burst ¹

1993 • 184 citations

Absence of both the 91kD and 22kD subunits of human neutrophil cytochrome b in two genetic forms of chronic granulomatous disease

1989 • 163 citations

Topological Mapping of Neutrophil Cytochrome b Epitopes with Phage-display Libraries

1995 • 162 citations

Defences of the bovine mammary gland against infection and prospects for their enhancement

1985 • 150 citations

Mapping sites of interaction of p47-phox and flavocytochrome b with random-sequence peptide phage display libraries.

1995 • 148 citations

Ultrastructural localization of cytochrome b in the membranes of resting and phagocytosing human granulocytes.

1990 • 145 citations

The Respiratory Burst Oxidase and the Molecular Genetics of Chronic Granulomatous Disease

1993 • 130 citations

Regulation of the phagocyte respiratory burst by small GTP-binding proteins

1995 • 125 citations

A structural model for the nucleotide binding domains of the flavocytochrome b_–245 β‐chain

1993 • 124 citations

Interaction Between the Respiratory Burst Activity of Neutrophil Leukocytes and Experimentally Induced Escherichia coli Mastitis in Cows

1990 • 121 citations

Cytochrome b558, a component of the phagocyte NADPH oxidase, is a flavoprotein

1992 • 118 citations

Cytochrome b-558 α-subunit cloning and expression in rat aortic smooth muscle cells

1995 • 110 citations

A point mutation in gp91-phox of cytochrome b558 of the human NADPH oxidase leading to defective translocation of the cytosolic proteins p47-phox and p67-phox.

1994 • 109 citations

Cytochrome b-245 from human neutrophils is a glycoprotein

1985 • 103 citations

Analysis of glycosylation sites on gp91phox, the flavocytochrome of the NADPH oxidase, by site-directed mutagenesis and translation in vitro

1997 • 99 citations

Molecular basis of oxidative damage by leukocytes

1993 • 96 citations

Activated or dominant inhibitory mutants of Rap1A decrease the oxidative burst of Epstein-Barr virus-transformed human B lymphocytes.

1994 • 96 citations

Human neutrophil cytochrome b contains multiple hemes. Evidence for heme associated with both subunits.

1992 • 95 citations

The formation and biologic significance of phagocyte-derived oxidants.

1995 • 91 citations

The lateral organization of components of the membrane skeleton and superoxide generation in the plasma membrane of stimulated human neutrophils

1989 • 90 citations

The phagocyte 47-kilodalton cytosolic oxidase protein is an early reactant in activation of the respiratory burst.

1990 • 89 citations

The Role of the Neutrophil in Rheumatoid Arthritis

1991 • 89 citations

Direct evidence for interaction between COOH-terminal regions of cytochrome b558 subunits and cytosolic 47-kDa protein during activation of an O(2-)-generating system in neutrophils.

1992 • 78 citations

The quaternary structure of the plasma membrane b-type cytochrome of human granulocytes

1988 • 74 citations

The respiratory burst of bovine neutrophilis

1985 • 73 citations

Stoichiometry of p22-phox and gp91-phox in phagocyte cytochrome b558

1995 • 65 citations

Cloning of murine gp91phox cDNA and functional expression in a human X- linked chronic granulomatous disease cell line

1996 • 65 citations

The role of the neutrophil in inflammatory diseases of the lung.

1990 • 57 citations

Cost benefit analysis of bovine mastitis in the UK

1992 • 53 citations

Polymorphonuclear Leukocyte Function

1985 • 52 citations

Clinical manifestations of leukocyte adhesion deficiency in cattle: 14 cases (1977-1991).

1993 • 48 citations

Clinical manifestations of leukocyte adhesion deficiency in cattle: 14 cases (1977-1991)

1993 • 42 citations

The electron transport chain of the microbicidal oxidase of phagocytic cells and its involvement in the molecular pathology of chronic granulomatous disease

1989 • 41 citations

Interleukin-4 suppresses the expression of macrophage NADPH oxidase heavy chain subunit (gp91-phox)

1995 • 40 citations

Structure of human phagocyte cytochrome b and its relationship to microbicidal superoxide production.

1995 • 35 citations

Cytosolic oxidase factors in the NADPH‐dependent oxidase of human neutrophils

1993 • 30 citations

Complementary DNA for the mouse homolog of the small subunit of human cytochrome b558

1989 • 28 citations

Phagocytic activity of bovine polymorphonuclear neutrophil leucocytes

1994 • 27 citations

Molecular basis of oxidative damage by leukocytes

1991 • 25 citations

Cloning and expression of the gene encoding the porcine NADPH oxidase light-chain subunit (p22-phox)

1994 • 12 citations

Identification of neutrophil NADPH oxidase proteins gp91-phox, p22-phox, p67-phox, and p47-phox in mammalian species.

1996 • 8 citations

Identification of neutrophil NADPH oxidase proteins gp91-phox, p22-phox, p67-phox, and p47-phox in mammalian species

1996 • 7 citations

Activated or dominant inhibitory mutants of Rap1A decrease the oxidative burst of Epstein-Barr virus-transformed human B lymphocytes

1994 • 2 citations