Mammalian and Escherichia coli signal recognition particles

The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

1987 • 2,403 citations

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1

1993 • 2,360 citations

Secretory protein translocation across membranes—the role of the ‘docking protein’

1982 • 648 citations

The binding cascade of SecB to SecA to SecYE mediates preprotein targeting to the E. coli plasma membrane

1990 • 561 citations

Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle

1989 • 474 citations

Transcending the impenetrable: How proteins come to terms with membranes

1988 • 471 citations

ΔμH+ and ATP function at different steps of the catalytic cycle of preprotein translocase

1991 • 456 citations

A mammalian homolog of SEC61p and SECYp is associated with ribosomes and nascent polypeptides during translocation

1992 • 450 citations

A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum.

1987 • 418 citations

SecA protein hydrolyzes ATP and is an essential component of the protein translocation ATPase of Escherichia coli.

1989 • 406 citations

Transient association of newly synthesized unfolded proteins with the heat-shock GroEL protein

1988 • 388 citations

Transport of Proteins Across the Endoplasmic Reticulum Membrane

1992 • 366 citations

Homology of 54K protein of signal-recognition particle, docking protein and two E. coli proteins with putative GTP–binding domains

1989 • 357 citations

The Rieske protein from Paracoccus denitrificans is inserted into the cytoplasmic membrane by the twin‐arginine translocase

2006 • 308 citations

The signal recognition particle receptor mediates the GTP-dependent displacement of SRP from the signal sequence of the nascent polypeptide

1989 • 293 citations

An E. coli Ribonucleoprotein Containing 4.5 S RNA Resembles Mammalian Signal Recognition Particle

1990 • 285 citations

The E. coli ffh gene is necessary for viability and efficient protein export

1992 • 268 citations

The methionine-rich domain of the 54 kd protein subunit of the signal recognition particle contains an RNA binding site and can be crosslinked to a signal sequence.

1990 • 256 citations

SecA interacts with secretory proteins by recognizing the positive charge at the amino terminus of the signal peptide in Escherichia coli.

1990 • 229 citations

DnaK and DnaJ heat shock proteins participate in protein export in Escherichia coli.

1992 • 214 citations

E. coli 4.5S RNA is part of a ribonucleoprotein particle that has properties related to signal recognition particle

1990 • 212 citations

Signal-sequence recognition by an Escherichia coli ribonucleoprotein complex

1992 • 184 citations

SRP-RNA sequence alignment and secondary structure

1991 • 181 citations

Human SRP RNA and E. coli 4.5S RNA contain a highly homologous structural domain

1988 • 178 citations

The SecA and SecY subunits of translocase are the nearest neighbors of a translocating preprotein, shielding it from phospholipids.

1993 • 176 citations

The 54-kD protein of signal recognition particle contains a methionine-rich RNA binding domain.

1990 • 170 citations

A new cell division operon inEscherichia coli

1986 • 156 citations

Molecular chaperones and protein translocation across the Escherichia coli inner membrane

1991 • 143 citations

Small Ribonucleic Acids of Escherichia coli

1973 • 115 citations

Functional substitution of the signal recognition particle 54-kDa subunit by its Escherichia coli homolog.

1993 • 109 citations

The nucleotide sequence of an Escherichia coli operon containing genes for the tRNA(m1G)methyltransferase, the ribosomal proteins S16 and L19 and a 21-K polypeptide.

1983 • 108 citations

Highly selective binding of nascent polypeptides by an Escherichia coli chaperone protein in vivo

1993 • 107 citations

The signal sequence interacts with the methionine-rich domain of the 54-kD protein of signal recognition particle.

1991 • 101 citations

Mutations in the gene for EF-G reduce the requirement for 4.5S RNA in the growth of E. coli

1987 • 83 citations

GTPase domain of the 54-kD subunit of the mammalian signal recognition particle is required for protein translocation but not for signal sequence binding.

1993 • 78 citations

Heat-shock proteins can substitute for SecB function during protein export in Escherichia coli.

1991 • 73 citations

Functional dissection of the signal recognition particle

1988 • 70 citations

Time of action of 4·5 S RNA in Escherichia coli translation

1989 • 64 citations

The Escherichia coli cell division proteins FtsY, FtsE and FtsX are inner membrane-associated

1987 • 55 citations

Evolutionary conserved nucleotides within theE.coli4.5S RNA are required for association with P48in vitroand for optimal functionin vivo

1992 • 50 citations

A gene in the archaebacterium Sulfolobus solfataricus that codes for a protein equivalent to the alpha subunits of the signal recognition particle receptor in eukaryotes

1991 • 32 citations

Localised mutagenesis of the fts YEX operon conditionally lethal missense substitutions in the FtsE cell division protein of Escherichia coli are similar to those found in the cystic fibrosis transmembrane conductance regulator protein (CFTR) of human patients

1992 • 29 citations

4.5S RNA: does form predict function?

1991 • 24 citations

A signal recognition particle in Escherichia coli?

1993 • 13 citations