Binary cell death decision regulated by unequal partitioning of Numb at mitosis

Notch Signaling: Cell Fate Control and Signal Integration in Development

1999 • 5,826 citations

The embryonic cell lineage of the nematode Caenorhabditis elegans

1983 • 4,070 citations

Genetic Control of Programmed Cell Death in Drosophila

1994 • 1,028 citations

Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells

1994 • 749 citations

Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector.

1989 • 688 citations

The head involution defective gene of Drosophila melanogaster functions in programmed cell death.

1995 • 685 citations

Programmed cell death: alive and well in the new millennium

2001 • 663 citations

Control of Daughter Cell Fates during Asymmetric Division: Interaction of Numb and Notch

1996 • 656 citations

The Embryonic Central Nervous System Lineages ofDrosophila melanogaster

1996 • 523 citations

Senseless, a Zn Finger Transcription Factor, Is Necessary and Sufficient for Sensory Organ Development in Drosophila

2000 • 509 citations

The Drosophila Caspase Inhibitor DIAP1 Is Essential for Cell Survival and Is Negatively Regulated by HID

1999 • 499 citations

Asymmetric segregation of Numb and Prospero during cell division

1995 • 489 citations

Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei.

1993 • 421 citations

The Embryonic Central Nervous System Lineages ofDrosophila melanogaster

1997 • 415 citations

grim, a novel cell death gene in Drosophila.

1996 • 414 citations

Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms

2002 • 364 citations

Correlating Notch Signaling with Thymocyte Maturation

1998 • 350 citations

The PROSPERO transcription factor is asymmetrically localized to the cell cortex during neuroblast mitosis in Drosophila

1996 • 333 citations

Asymmetric segregation of the homeodomain protein Prospero duringDrosophila development

1995 • 330 citations

Patterns of expression of cut, a protein required for external sensory organ development in wild-type and cut mutant Drosophila embryos.

1990 • 284 citations

Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1

2002 • 272 citations

A Steroid-Triggered Transcriptional Hierarchy Controls Salivary Gland Cell Death during Drosophila Metamorphosis

2000 • 269 citations

Development and Determination of Hairs and Bristles in the Milkweed Bug, Oncopeltus Fasciatus (Lygaeidae, Hemiptera)

1966 • 243 citations

Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition

2002 • 199 citations

Two C. elegans genes control the programmed deaths of specific cells in the pharynx

1991 • 171 citations

Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2

1996 • 164 citations

Development of the Eye

2002 • 161 citations

Subcellular localization of Suppressor of Hairless in Drosophila sense organ cells during Notch signalling

1996 • 148 citations

Monocytes express high amounts of Notch and undergo cytokine specific apoptosis following interaction with the Notch ligand, Delta-1

2000 • 134 citations

sickle, a Novel Drosophila Death Gene in the reaper/hid/grim Region, Encodes an IAP-Inhibitory Protein

2002 • 131 citations

The C. elegans Cell Death Specification Gene ces-1 Encodes a Snail Family Zinc Finger Protein

1999 • 125 citations

Drosophila Morgue is an F box/ubiquitin conjugase domain protein important for grim-reaper mediated apoptosis

2002 • 123 citations

The Damage-Responsive Drosophila Gene sickle Encodes a Novel IAP Binding Protein Similar to but Distinct from reaper, grim, and hid

2002 • 121 citations

Drosophila sickle Is a Novel grim-reaper Cell Death Activator

2002 • 114 citations

Asymmetric distribution of the C. elegans HAM-1 protein in neuroblasts enables daughter cells to adopt distinct fates

1996 • 65 citations

Structure and regulation of a complex locus: the cut gene of Drosophila.

1995 • 64 citations

Hox gene control of segment-specific bristle patterns in Drosophila

2002 • 60 citations

Lineage, cell polarity and inscuteable function in the peripheral nervous system of the Drosophila embryo

2001 • 48 citations

Functional Analysis of the Numb Phosphotyrosine-binding Domain Using Site-directed Mutagenesis

1998 • 40 citations

Visualizing mRNA by in situ hybridization using 'high resolution' and sensitive tyramide signal amplification

1998 • 31 citations

Development of the D. melanogaster caudal segments involves suppression of the ventral regions of A8, A9 and A10

1992 • 28 citations

T-cell development:

1999 • 11 citations