A Steroid-Triggered Transcriptional Hierarchy Controls Salivary Gland Cell Death during Drosophila Metamorphosis

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The drosophila EcR gene encodes an ecdysone receptor, a new member of the steroid receptor superfamily

1991 • 958 citations

Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death

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Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation

1992 • 719 citations

The head involution defective gene of Drosophila melanogaster functions in programmed cell death.

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Apoptosis and disease

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A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors.

1996 • 637 citations

An apoptosis-inhibiting gene from a nuclear polyhedrosis virus encoding a polypeptide with Cys/His sequence motifs

1994 • 530 citations

Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle

1993 • 519 citations

Control of Programmed Cell Death by the Baculovirus Genes p35 and iap

1994 • 517 citations

The Drosophila Caspase Inhibitor DIAP1 Is Essential for Cell Survival and Is Negatively Regulated by HID

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The E75 ecdysone-inducible gene responsible for the 75B early puff in Drosophila encodes two new members of the steroid receptor superfamily.

1990 • 483 citations

The Drosophila Gene hid Is a Direct Molecular Target of Ras-Dependent Survival Signaling

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Flies on steroids — Drosophila metamorphosis and the mechanisms of steroid hormone action

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The Drosophila Broad-Complex encodes a family of related proteins containing zinc fingers.

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grim, a novel cell death gene in Drosophila.

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Cell Killing by the Drosophila Gene reaper

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APOPTOSIS AND DISEASE: Regulation and Clinical Relevance of Programmed Cell Death

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Coordination of Drosophila Metamorphosis by Two Ecdysone-Induced Nuclear Receptors

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Drosophila Ecdysone Receptor Mutations Reveal Functional Differences among Receptor Isoforms

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DRONC, an ecdysone-inducible Drosophila caspase

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Cooperative functions of the reaper and head involution defective genes in the programmed cell death of Drosophila central nervous system midline cells

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Sequential gene activation by ecdysone in polytene chromosomes of Drosophila melanogaster

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An ecdysone response element in the Drosophila hsp27 promoter

1987 • 268 citations

Molecular Analysis of the Initiation of Insect Metamorphosis: A Comparative Study of Drosophila Ecdysteroid-Regulated Transcription

1993 • 267 citations

Drosophila Melanogaster: Practical Uses in Cell and Molecular Biology

1994 • 251 citations

The Drosophila βFTZ-F1 Orphan Nuclear Receptor Provides Competence for Stage-Specific Responses to the Steroid Hormone Ecdysone

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Interactions and developmental effects of mutations in the Broad-Complex of Drosophila melanogaster.

1988 • 229 citations

A molecular mechanism for the stage specificity of the Drosophila prepupal genetic response to ecdysone

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Inhibition of Reaper-induced apoptosis by interaction with inhibitor of apoptosis proteins (IAPs)

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The Monomer-Binding Orphan Receptor Rev-Erb Represses Transcription as a Dimer on a Novel Direct Repeat

1995 • 204 citations

Inhibitor of Apoptosis Proteins Physically Interact with and Block Apoptosis Induced by Drosophila Proteins HID and GRIM

1998 • 203 citations

Differential expression of Broad-Complex transcription factors may forecast tissue-specific developmental fates during Drosophila metamorphosis

1994 • 176 citations

The RXR homolog Ultraspiracle is an essential component of the Drosophila ecdysone receptor

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The Drosophila E93 Gene from the 93F Early Puff Displays Stage- and Tissue-Specific Regulation by 20-Hydroxyecdysone

1995 • 155 citations

Chapter 29 Methods for Quantitative Analysis of Transcription in Larvae and Prepupae

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A cloning method to identify caspases and their regulators in yeast: Identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1

1999 • 151 citations

An emerging blueprint for apoptosis in Drosophila

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Hormonal control of programmed cell death/apoptosis

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Ectopic expression and function of the Antp and Scr homeotic genes: the N terminus of the homeodomain is critical to functional specificity

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Cytogenetic analysis of the 2B3-4-2B11 Region of the X-chromosome of Drosophila melanogaster

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Cloning and characterization of a corepressor and potential component of the nuclear hormone receptor repression complex

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The Drosophila E74 gene is required for metamorphosis and plays a role in the polytene chromosome puffing response to ecdysone

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Regulation of apoptosis by steroid hormones

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A functional Rev-erb alpha responsive element located in the human Rev-erb alpha promoter mediates a repressing activity.

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Mechanisms and control of programmed cell death in invertebrates

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The ecdysone-induced puffing cascade in Drosophila salivary glands: a Broad-Complex early gene regulates intermolt and late gene transcription.

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Expression and Function of the ultraspiracle (usp) Gene during Development of Drosophila melanogaster

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Activation of thereaperGene during Ectopic Cell Killing inDrosophila

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Programmed cell death—IV. The influence of drugs on the breakdown of the intersegmental muscles of silkmoths

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Cytogenetic analysis of the 2B3-4-2B11 Region of the X chromosome of Drosophila melanogaster

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TheDrosophila Broad-ComplexEarly Gene Directly Regulates Late Gene Transcription during the Ecdysone-Induced Puffing Cascade

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Genes That Induce Apoptosis: Transcriptional Regulation in Identified, Doomed Neurons of theDrosophilaCNS

1997 • 89 citations

The ecdysone-inducible Broad-complex and E74 early genes interact to regulate target gene transcription and Drosophila metamorphosis.

1995 • 88 citations

Mutations in a steroid hormone-regulated gene disrupt the metamorphosis of internal tissues in Drosophila: salivary glands, muscle, and gut

1992 • 81 citations

Genetic and hormonal regulation of the death of peptidergic neurons in theDrosophila central nervous system

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Ecdysone regulation of the Drosophila Sgs-4 gene is mediated by the synergistic action of ecdysone receptor and SEBP 3.

1995 • 66 citations

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1996 • 64 citations

Molecular analysis of a steroid-induced regulatory hierarchy: the Drosophila E74A protein directly regulates L71-6 transcription.

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Ecdysone-Regulated Chromosome Puffing in Drosophila melanogaster

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Structure and expression of the br-c locus in Drosophila melanogaster (Diptera: Drosophilidae)

2013 • 8 citations