Regulatory functions of self-restricted MHC class II allopeptide-specific Th2 clones in vivo

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

Regulatory T Cell Clones Induced by Oral Tolerance: Suppression of Autoimmune Encephalomyelitis

1994 • 1,995 citations

Lymphocyte responses and cytokines

1994 • 1,860 citations

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy

1995 • 1,695 citations

"Infectious" Transplantation Tolerance

1993 • 890 citations

The Role of T-Cell Costimulatory Activation Pathways in Transplant Rejection

1998 • 585 citations

CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2.

1995 • 532 citations

Antibody-induced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and anti-apoptotic genes

1998 • 466 citations

Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppression

2000 • 448 citations

Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection

1996 • 416 citations

Chronic Allograft Rejection

1993 • 304 citations

CD4+ but not CD8+ cells are essential for allorejection.

1996 • 303 citations

INDIRECT ALLORECOGNITION OF MAJOR HISTOCOMPATIBILITY COMPLEX ALLOPEPTIDES IN HUMAN RENAL TRANSPLANT RECIPIENTS WITH CHRONIC GRAFT DYSFUNCTION1

1997 • 290 citations

IFN-gamma is critical for long-term allograft survival induced by blocking the CD28 and CD40 ligand T cell costimulation pathways.

1998 • 275 citations

T-Lymphocyte-Antigen Interactions in Transplant Rejection

1990 • 257 citations

IFN-γ Is Critical for Long-Term Allograft Survival Induced by Blocking the CD28 and CD40 Ligand T Cell Costimulation Pathways

1998 • 211 citations

IL-2 knockout recipient mice reject islet cell allografts.

1995 • 204 citations

CD28-B7 costimulatory blockade by CTLA4Ig prevents actively induced experimental autoimmune encephalomyelitis and inhibits Th1 but spares Th2 cytokines in the central nervous system.

1995 • 204 citations

Impaired Alloantigen-Mediated T Cell Apoptosis and Failure To Induce Long-Term Allograft Survival in IL-2-Deficient Mice

1998 • 178 citations

Blockade of T-cell costimulation prevents development of experimental chronic renal allograft rejection.

1996 • 170 citations

ARE Th2 HELPER T LYMPHOCYTES BENEFICIAL, DELETERIOUS, OR IRRELEVANT IN PROMOTING ALLOGRAFT SURVIVAL?1

1997 • 170 citations

Induction of immunity and oral tolerance with polymorphic class II major histocompatibility complex allopeptides in the rat.

1992 • 163 citations

T cell regulation in adult transplantation tolerance.

1996 • 144 citations

COMBINED COSTIMULATION BLOCKADE PLUS RAPAMYCIN BUT NOT CYCLOSPORINE PRODUCES PERMANENT ENGRAFTMENT1

1998 • 140 citations

The role of CD154-CD40 versus CD28-B7 costimulatory pathways in regulating allogeneic Th1 and Th2 responses in vivo

2000 • 135 citations

Blocking the CD28-B7 T cell costimulation pathway induces long term cardiac allograft acceptance in the absence of IL-4.

1997 • 129 citations

CHRONIC ALLOGRAFT REJECTION

1999 • 127 citations

Induction of "infectious" tolerance to MHC-incompatible cardiac allografts in CD4 monoclonal antibody-treated sensitized rat recipients.

1996 • 126 citations

Mechanisms of acquired thymic tolerance in experimental autoimmune encephalomyelitis: thymic dendritic-enriched cells induce specific peripheral T cell unresponsiveness in vivo.

1995 • 121 citations

Type 2 helper T cell-type cytokines and the development of "infectious" tolerance in rat cardiac allograft recipients.

1997 • 119 citations

MANIPULATION OF CYTOKINE NETWORKS IN TRANSPLANTATION

1997 • 99 citations

MECHANISMS OF ALLO-RECOGNITION

1994 • 94 citations

MECHANISMS OF ALLO-RECOGNITION

1994 • 85 citations

THE INDIRECT PATHWAY OF ALLORECOGNITION

1995 • 74 citations

Ex vivo treatment of antigen-presenting cells with CTLA4Ig and encephalitogenic peptide prevents experimental autoimmune encephalomyelitis in the Lewis rat.

1996 • 74 citations

Peptide-mediated immunosuppression

1997 • 73 citations

BALANCING THE IMMUNE SYSTEM FOR TOLERANCE

1997 • 71 citations

CELLULAR AND HUMORAL MECHANISMS OF VASCULARIZED ALLOGRAFT REJECTION INDUCED BY INDIRECT RECOGNITION OF DONOR MHC ALLOPEPTIDES1

1999 • 67 citations

Limited usage of T cell receptor V beta genes by allopeptide-specific T cells.

1993 • 63 citations

MECHANISMS OF INDIRECT ALLORECOGNITION IN GRAFT REJECTION

1996 • 53 citations

MECHANISMS OF INDIRECT ALLORECOGNITION

1998 • 46 citations

Transplantation tolerance: The concept and its applicability

1999 • 44 citations

Deleted Work

1955 • 0 citations