A Long-Term Memory Obtained by Genetic Immunization Results in Full Protection from a Mammary Adenocarcinoma Expressing an EBV Gene

Direct Gene Transfer into Mouse Muscle in Vivo

1990 • 3,985 citations

Heterologous Protection Against Influenza by Injection of DNA Encoding a Viral Protein

1993 • 2,330 citations

Epstein-Barr Virus

1986 • 2,255 citations

Epstein-Barr virus and its replication

1996 • 1,621 citations

Genetic immunization is a simple method for eliciting an immune response

1992 • 1,505 citations

DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations.

1993 • 1,122 citations

DNA VACCINES

1997 • 977 citations

DNA–based immunization by in vivo transfection of dendritic cells

1996 • 849 citations

HUMAN CYTOTOXIC T LYMPHOCYTE RESPONSES TO EPSTEIN-BARR VIRUS INFECTION

1997 • 769 citations

Gene inoculation generates immune responses against human immunodeficiency virus type 1.

1993 • 655 citations

In vivo and in vitro gene transfer to mammalian somatic cells by particle bombardment.

1990 • 603 citations

Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization.

1997 • 566 citations

Gene vaccination with naked plasmid DNA: mechanism of CTL priming.

1996 • 494 citations

Manipulation of the immune response to a plasmid-encoded viral antigen by coinoculation with plasmids expressing cytokines

1995 • 486 citations

Cancer vaccines

1998 • 422 citations

Localization of Epstein-Barr virus cytotoxic T cell epitopes using recombinant vaccinia: implications for vaccine development.

1992 • 402 citations

Plasmid DNA Is Superior to Viral Vectors for Direct Gene Transfer into Adult Mouse Skeletal Muscle

1993 • 314 citations

The dominant role of bone marrow-derived cells in CTL induction following plasmid DNA immunization at different sites.

1997 • 257 citations

DNA immunization induces protective immunity against B–cell lymphoma

1996 • 252 citations

Enhanced responses to a DNA vaccine encoding a fusion antigen that is directed to sites of immune induction

1998 • 251 citations

Epstein-Barr virus strategy in normal and neoplastic B cells

1994 • 251 citations

Modulation of amplitude and direction ofin vivo immune responses by co-administration of cytokine gene expression cassettes with DNA immunogens

1998 • 241 citations

The Epstein-Barr Virus and Neoplasia

1975 • 235 citations

Biological features of genetic immunization

1997 • 226 citations

Specific Immune Induction Following DNA-Based Immunization Through In Vivo Transfection and Activation of Macrophages/Antigen-Presenting Cells

1998 • 223 citations

Immunization of non-human primates with DNA vaccines

1997 • 223 citations

Examination of Parameters Affecting the Elicitation of Humoral Immune Responses by Particle Bombardment-Mediated Genetic Immunization

1993 • 188 citations

First EBV vaccine trial in humans using recombinant vaccinia virus expressing the major membrane antigen.

1995 • 158 citations

Discussion

1997 • 121 citations

Viruses and cancer

1991 • 118 citations

Tumor cells transfected with a bacterial heat-shock gene lose tumorigenicity and induce protection against tumors.

1993 • 98 citations

Vaccine developments

1998 • 68 citations

Post-Transplant EBV Induced Lymphoproliferative Disorders

1997 • 68 citations

Immunotherapy for Epstein-Barr Virus-Associated Cancers

1998 • 63 citations

Therapeutic gene delivery in human B-lymphoblastoid cells by engineered non-transforming infectious Epstein–Barr virus

1995 • 62 citations

DNA Immunization of Newborn Mice with a Plasmid-Expressing Nucleoprotein of Influenza Virus

1996 • 62 citations

Switching viral latency to viral lysis: a novel therapeutic approach for Epstein-Barr virus-associated neoplasia.

1996 • 61 citations

Strategies Involved in Developing an Effective Vaccine for EBV-Associated Diseases

1996 • 56 citations

Epstein–Barr virus–driven gene therapy for EBV–related lymphomas

1996 • 49 citations

Growth arrest of Epstein–Barr virus immortalized B lymphocytes by adenovirus-delivered ribozymes

1997 • 45 citations

The effect of interferon-γ on genetic immunization

1997 • 45 citations

Use of Epstein-Barr Virus Nuclear Antigen-1 in Targeted Therapy of EBV-Associated Neoplasia

1996 • 39 citations

Killing Epstein-Barr Virus-Positive B Lymphocytes by Gene Therapy: Comparing the Efficacy of Cytosine Deaminase and Herpes Simplex Virus Thymidine Kinase

1996 • 33 citations

Genetic Immunization

1996 • 32 citations

Current Perspectives on the Molecular Pathogenesis of Virus-Induced Cancers in Human Immunodeficiency Virus Infection and Acquired Immunodeficiency Syndrome

1998 • 25 citations

Thirteen new mammary tumor cell lines from different mouse strains

1980 • 23 citations

A strategy for specific targeting of therapeutic agents to tumour cells of virus-associated cancers

1997 • 18 citations

Epstein-Barr virus transforming proteins

1994 • 18 citations

Issues Related to Development of Epstein-Barr Virus Vaccines

1996 • 16 citations

Differential immunogenicity of Epstein-Barr virus (EBV) encoded growth transformation-associated antigens in a murine model system

1997 • 14 citations

Potential Antigenic Targets on Epstein ‐ Barr Virus‐Associated Tumours and the Host Response

2007 • 13 citations

Genetic vaccines — a revolution in vaccinology?

1997 • 11 citations

Induction of tumor-specific T cell response by cognating tumor cells with foreign antigen-primed Th cells

1998 • 7 citations

The Development of Epstein–Barr Virus Vaccines

2006 • 6 citations

The Promise and the Reality of Viral Vaccines against Cancer

1993 • 5 citations

The Development of Epstein-Barr Virus Vaccines

1995 • 3 citations