Induction of tumor-specific T cell response by cognating tumor cells with foreign antigen-primed Th cells

The B7 and CD28 receptor families

1994 • 1,342 citations

Human naive and memory T cells

1988 • 793 citations

The JAM test A simple assay for DNA fragmentation and cell death

1991 • 632 citations

Adoptive T Cell Therapy of Tumors: Mechanisms Operative in the Recognition and Elimination of Tumor Cells

1991 • 619 citations

Immune interferon activates multiple class II major histocompatibility complex genes and the associated invariant chain gene in human endothelial cells and dermal fibroblasts.

1984 • 579 citations

Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells.

1994 • 498 citations

Paracrine Cytokine Adjuvants in Cancer Immunotherapy

1995 • 373 citations

Costimulation of T cells for tumor immunity

1993 • 324 citations

Receptor-directed focusing of lymphokine release by helper T cells

1988 • 284 citations

Spatial relationships of microtubule-organizing centers and the contact area of cytotoxic T lymphocytes and target cells.

1982 • 283 citations

Tumor Eradication by Adoptive Transfer of Cytototic T Lymphocytes

1992 • 281 citations

Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated major histocompatibility complex class II molecules.

1993 • 274 citations

Differential activation requirements for virgin and memory T cells.

1988 • 271 citations

The specific direct interaction of helper T cells and antigen-presenting B cells.

1986 • 246 citations

Cytokine gene transfer in tumor inhibition and tumor therapy: where are we now?

1994 • 245 citations

Major histocompatibility complex class II+B7-1+ tumor cells are potent vaccines for stimulating tumor rejection in tumor-bearing mice.

1995 • 190 citations

Rejection of mouse sarcoma cells after transfection of MHC class II genes.

1990 • 171 citations

Toward a Genetic Analysis of Tumor Rejection Antigens

1992 • 151 citations

Costimulation of tumor-reactive CD4+ and CD8+ T lymphocytes by B7, a natural ligand for CD28, can be used to treat established mouse melanoma.

1994 • 145 citations

Specificity and longevity of antitumor immune responses induced by B7-transfected tumors.

1994 • 141 citations

Immunosuppressive Factors in Human Cancer

1992 • 131 citations

Perspectives on the Role of Mhc Antigens in Normal and Malignant Cell Development

1989 • 124 citations

Differential regulation of HLA-DR mRNAs and cell surface antigens by interferon.

1983 • 112 citations

Induction in a murine tumor of immunogenic tumor variants by transfection with a foreign gene.

1988 • 110 citations

Requirement for recognition of class II molecules and processed tumor antigen for optimal generation of syngeneic tumor-specific class I-restricted CTL.

1986 • 97 citations

Stimulation of human naive and memory T helper cells with bacterial superantigen. Naive CD4+45RA+ T cells require a costimulatory signal mediated through the LFA-1/ICAM-1 pathway.

1992 • 78 citations

Immunologic approach to cancer.

1970 • 74 citations

The augmentation of in vitro and in vivo tumor-specific T cell-mediated immunity by amplifier T lymphocytes.

1980 • 73 citations

Helper strategy in tumor immunology: Expansion of helper lymphocytes and utilization of helper lymphokines for experimental and clinical immunotherapy

1988 • 69 citations

Xenogenization of a mouse lung carcinoma (3LL) by transfection with an allogeneic class I major histocompatibility complex gene (H-2Ld).

1987 • 57 citations

The augmentation of tumor‐specific immunity by virus help. II. Enhanced induction of cytotoxic T lymphocyte and antibody responses to tumor antigens by vaccinia virus‐reactive helper T cells

1984 • 56 citations

Coupling PPD to tumour cells enhances their antigenicity in BCG-primed mice

1978 • 42 citations

Rejection of K1735 murine melanoma in syngeneic hosts requires expression of MHC class I antigens and either class II antigens or IL-2.

1993 • 42 citations

Modes of cell:cell communication in the immune system

1985 • 37 citations

Enhanced TNP-reactive helper T cell activity and its utilization in the induction of amplified tumor immunity that results in tumor regression.

1984 • 36 citations

Alteration of immunogenicity of xenogenized tumor cells in syngeneic rats by the immune responses to virus-associated antigens produced on immunizing cells.

1983 • 25 citations

Augmented induction of tumor-specific resistance by priming with Mycobacterium tuberculosis (TBC) and subsequent immunization with PPD-coupled syngeneic tumor cells.

1980 • 17 citations

The augmentation of tumor-specific immunity using haptenic muramyl dipeptide (MDP) derivatives

1988 • 6 citations

Induction of transplantation resistance to murine L1210 leukemia cells in BCG-primed mice by immunization with tuberculin protein-coupled L1210 cells.

1984 • 3 citations

The active immunotherapy of a 3-methylcholanthrene-induced rat tumor with Friend virus-infected (xenogenized) tumor cells.

1986 • 2 citations