Vaccine developments

Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd

1995 • 5,571 citations

Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells

1998 • 2,916 citations

Biodegradation and biocompatibility of PLA and PLGA microspheres

1997 • 2,481 citations

Smallpox and its eradication

1989 • 1,365 citations

Protective Effects of a Live Attenuated SIV Vaccine with a Deletion in the nef Gene

1992 • 1,025 citations

DNA VACCINES

1997 • 977 citations

Adjuvants—a classification and review of their modes of action

1997 • 668 citations

Oral Immunization with a Recombinant Bacterial Antigen Produced in Transgenic Plants

1995 • 631 citations

Expression of Norwalk virus capsid protein in transgenic tobacco and potato and its oral immunogenicity in mice.

1996 • 577 citations

Adjuvants for human vaccines—current status, problems and future prospects

1995 • 546 citations

The Prevalence of Drug-ResistantStreptococcus pneumoniaeIn Atlanta

1995 • 519 citations

Pathogenicity of Live, Attenuated SIV After Mucosal Infection of Neonatal Macaques

1995 • 491 citations

Oral Somatic Transgene Vaccination Using Attenuated S. typhimurium

1997 • 409 citations

Induction of virus‐specific cytotoxic T lymphocytes in vivo by liposome‐entrapped mRNA

1993 • 408 citations

Sindbis Virus: An Efficient, Broad Host Range Vector for Gene Expression in Animal Cells

1989 • 402 citations

Efficacy of a food plant-based oral cholera toxin B subunit vaccine

1998 • 351 citations

Safety of and immunological response to a recombinant vaccinia virus vaccine expressing HIV envelope glycoprotein

1991 • 334 citations

Infectious poxvirus vectors have capacity for at least 25 000 base pairs of foreign DNA

1983 • 311 citations

Attenuated Shigella as a DNA Delivery Vehicle for DNA-Mediated Immunization

1995 • 292 citations

New generation vaccines

1998 • 290 citations

Delivery of antigen-encoding plasmid DNA into the cytosol of macrophages by attenuated suicide Listeria monocytogenes

1998 • 251 citations

Enhancement of MHC class I-restricted peptide-specific T cell induction by a DNA prime/MVA boost vaccination regime

1998 • 227 citations

Alphavirus-based expression vectors: strategies and applications.

1996 • 224 citations

Protection by attenuated simian immunodeficiency virus in macaques against challenge with virus-infected cells

1995 • 219 citations

Declining Incidence of Haemophilus influenzae Type b Disease Since Introduction of Vaccination

1993 • 197 citations

In vivo absorption of aluminium-containing vaccine adjuvants using 26Al

1997 • 193 citations

DNA Immunization against Herpes Simplex Virus: Enhanced Efficacy Using a Sindbis Virus-Based Vector

1998 • 183 citations

Development and characterization of cold-adapted viruses for use as live virus vaccines

1985 • 165 citations

Synergistic action of cholera toxin B subunit (and Escherichia coli heat-labile toxin B subunit) and a trace amount of cholera whole toxin as an adjuvant for nasal influenza vaccine

1994 • 148 citations

A partially attenuated simian immunodeficiency virus induces host immunity that correlates with resistance to pathogenic virus challenge

1994 • 142 citations

Immunization with a vaccinia virus recombinant expressing herpes simplex virus type 1 glycoprotein D: long-term protection and effect of revaccination

1988 • 133 citations

Humoral, mucosal, and cellular immunity in response to a human immunodeficiency virus type 1 immunogen expressed by a Venezuelan equine encephalitis virus vaccine vector

1997 • 121 citations

A viral vaccine vector that expresses foreign genes in lymph nodes and protects against mucosal challenge

1996 • 110 citations

Candidate AIDS Vaccines

1995 • 104 citations

Human safety and immunogenicity of a canarypox-rabies glycoprotein recombinant vaccine: an alternative poxvirus vector system

1996 • 100 citations

Vaccination with two different vaccinia recombinant viruses: long-term inhibition of secondary vaccination

1993 • 93 citations

In vivo distribution of radioactivity in mice after injection of biodegradable polymer microspheres containing 14C-labeled tetanus toxoid

1996 • 83 citations

Plasmid DNA encoding replicating foot-and-mouth disease virus genomes induces antiviral immune responses in swine

1997 • 82 citations

Attenuated Listeria monocytogenes as a live vector for induction of CD8⁺ T cells in vivo: a study with the nucleoprotein of the lymphocytic choriomeningitis virus

1995 • 76 citations

Evaluation of the protective efficacy of a serotype 1 bovine-human rotavirus reassortant vaccine in infants

1995 • 56 citations

Prospects for new vaccines against tuberculosis

1995 • 52 citations

HIV Vaccine Development: A Progress Report

1994 • 46 citations

Hypothesis: How Licensed Vaccines Confer Protective Immunity

1996 • 34 citations

Classics of Medicine and Surgery

1961 • 12 citations

"Attenuated" Simian Immunodeficiency Virus in Macaque Neonates

1996 • 11 citations