Dual Regulation of NMDA Receptor Functions by Direct Protein-Protein Interactions with the Dopamine D1 Receptor

Mitochondria and Apoptosis

1998 • 8,909 citations

Glutamate receptor ion channels

2005 • 3,667 citations

Dopamine Receptors: From Structure to Function

1998 • 3,489 citations

Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways

2002 • 1,612 citations

Signalling through the lipid products of phosphoinositide-3-OH kinase

1997 • 1,314 citations

NMDA-dependent superoxide production and neurotoxicity

1993 • 1,188 citations

Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1

1991 • 1,157 citations

Calcium: still center-stage in hypoxic-ischemic neuronal death

1995 • 921 citations

The Neurobiology of Slow Synaptic Transmission

2001 • 873 citations

Receptors for Dopamine and Somatostatin: Formation of Hetero-Oligomers with Enhanced Functional Activity

2000 • 866 citations

Specific Coupling of NMDA Receptor Activation to Nitric Oxide Neurotoxicity by PSD-95 Protein

1999 • 821 citations

Regulation of AMPA Receptor–Mediated Synaptic Transmission by Clathrin-Dependent Receptor Internalization

2000 • 687 citations

Impaired B Cell Development and Proliferation in Absence of Phosphoinositide 3-Kinase p85α

1999 • 642 citations

NMDA Channel Regulation by Channel-Associated Protein Tyrosine Kinase Src

1997 • 614 citations

Competitive binding of α-actinin and calmodulin to the NMDA receptor

1997 • 591 citations

How receptors talk to trimeric G proteins

1997 • 562 citations

Neuromodulatory actions of dopamine in the neostriatum are dependent upon the excitatory amino acid receptor subtypes activated.

1993 • 552 citations

Inactivation of NMDA Receptors by Direct Interaction of Calmodulin with the NR1 Subunit

1996 • 532 citations

Calcium-induced actin depolymerization reduces NMDA channel activity

1993 • 510 citations

Regulation of NMDA Receptors by an Associated Phosphatase-Kinase Signaling Complex

1999 • 497 citations

Regulation of NMDA channel function by endogenous Ca2+-dependent phosphatase

1994 • 483 citations

Direct binding and functional coupling of α-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis

2001 • 445 citations

Direct protein–protein coupling enables cross-talk between dopamine D5 and γ-aminobutyric acid A receptors

2000 • 437 citations

Dopamine D ₁ and adenosine A ₁ receptors form functionally interacting heteromeric complexes

2000 • 437 citations

Dopamine and N-Methyl-D- Aspartate Receptor Interactions in the Neostriatum

1998 • 358 citations

Molecular organization of the postsynaptic specialization

2001 • 330 citations

A Dopamine/D1 Receptor/Protein Kinase A/Dopamine- and cAMP-Regulated Phosphoprotein (M_r32 kDa)/Protein Phosphatase-1 Pathway Regulates Dephosphorylation of the NMDA Receptor

1998 • 322 citations

Mitochondria and Ca2+in cell physiology and pathophysiology

2000 • 312 citations

Distinct Influx Pathways, Not Calcium Load, Determine Neuronal Vulnerability to Calcium Neurotoxicity

1998 • 270 citations

Regulation of NMDA receptors in cultured hippocampal neurons by protein phosphatases 1 and 2A

1994 • 210 citations

Tyrosine Phosphatase STEP Is a Tonic Brake on Induction of Long-Term Potentiation

2002 • 205 citations

A Postsynaptic Interaction between Dopamine D₁and NMDA Receptors Promotes Presynaptic Inhibition in the Rat Nucleus Accumbens via Adenosine Release

1997 • 196 citations

Calcium, free radicals and excitotoxins in neuronal apoptosis

1998 • 195 citations

Dual Signaling Regulated by Calcyon, a D1 Dopamine Receptor Interacting Protein

2000 • 176 citations

Glutamate receptor phosphorylation and synaptic plasticity

1994 • 175 citations

Calmodulin Activates Phosphatidylinositol 3-Kinase

1997 • 165 citations

Modulatory Actions of Dopamine on NMDA Receptor-Mediated Responses Are Reduced in D_1A-Deficient Mutant Mice

1996 • 162 citations

Gain control of NMDA-receptor currents by intracellular sodium

1998 • 148 citations

The phosphoprotein DARPP-32 mediates cAMP-dependent potentiation of striatal N -methyl- <scp>d</scp> -aspartate responses

1997 • 138 citations

Delayed Antagonism of Calpain Reduces Excitotoxicity in Cultured Neurons

1995 • 91 citations

Inhibition of G protein-coupled receptor signaling by expression of cytoplasmic domains of the receptor.

1994 • 89 citations

Gain control of N-methyl-D-aspartate receptor activity by receptor-like protein tyrosine phosphatase alpha

2002 • 79 citations

Distinct Residues in the Carboxyl Tail Mediate Agonist-induced Desensitization and Internalization of the Human Dopamine D1 Receptor

2002 • 70 citations

Neuronal survival induced by neurotrophins requires calmodulin

2001 • 53 citations

Aurintricarboxylic Acid Prevents NMDA‐Mediated Excitotoxicity: Evidence for Its Action as an NMDA Receptor Antagonist

1993 • 46 citations

High affinity calmodulin target sequence in the signalling molecule PI 3‐kinase

1998 • 45 citations

Selective Inhibition of Heterotrimeric GsSignaling

2002 • 37 citations

High-affinity TCRs

2000 • 4 citations