Calmodulin Activates Phosphatidylinositol 3-Kinase

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

1994 • 3,249 citations

Phosphatidylinositol 3′-kinase is activated by association with IRS-1 during insulin stimulation.

1992 • 1,030 citations

Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin.

1994 • 923 citations

Phosphatidylinositol 3‐kinase

1994 • 649 citations

Activation of phosphatidylinositol 3-kinase by insulin.

1990 • 531 citations

Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling

1994 • 439 citations

IRS-1: Essential for Insulin- and IL-4-Stimulated Mitogenesis in Hematopoietic Cells

1993 • 401 citations

Expression and function of IRS-1 in insulin signal transmission.

1992 • 331 citations

The Effects of Wortmannin on Rat Skeletal Muscle

1995 • 320 citations

Activated Phosphatidylinositol 3-Kinase Is Sufficient to Mediate Actin Rearrangement and GLUT4 Translocation in 3T3-L1 Adipocytes

1996 • 239 citations

Membrane ruffling and signal transduction

1994 • 183 citations

Requirement for Phosphoinositide 3-Kinase in Insulin-Stimulated GLUT4 Translocation in 3T3-L1 Adipocytes

1995 • 143 citations

Calmodulin Modulates the Interaction between IQGAP1 and Cdc42

1997 • 137 citations

Phosphatidylinositol 3-kinase activity is required for early endosome fusion

1995 • 119 citations

The Pleckstrin Homology Domain in Insulin Receptor Substrate-1 Sensitizes Insulin Signaling

1995 • 113 citations

Phosphoinositide 3-Kinase Binds Constitutively to α/β-Tubulin and Binds to γ-Tubulin in Response to Insulin

1995 • 105 citations

Monoclonal antibody to calmodulin: Development, characterization, and comparison with polyclonal anti-calmodulin antibodies

1991 • 85 citations

The calmodulin antagonist, W-13, alters transcytosis, recycling, and the morphology of the endocytic pathway in Madin-Darby canine kidney cells.

1994 • 80 citations

Phosphorylation of the Platelet p47 Phosphoprotein Is Mediated by the Lipid Products of Phosphoinositide 3-Kinase

1995 • 75 citations

Signal transduction in neutrophil activation Phosphatidylinositol 3‐kinase is stimulated without tyrosine phosphorylation

1992 • 58 citations

Vertebrate Unconventional Myosins

1996 • 52 citations

Ca²⁺ Regulates Calmodulin Binding to IQ Motifs in IRS-1

1996 • 50 citations

Calmodulin Binds to the Basolateral Targeting Signal of the Polymeric Immunoglobulin Receptor

1996 • 41 citations

Effects of CGS 9343B (a Putative Calmodulin Antagonist) on Isolated Skeletal Muscle

1995 • 40 citations

Reduced level of calmodulin in PC12 cells induced by stable expression of calmodulin antisense RNA inhibits cell proliferation and induces neurite outgrowth

1996 • 31 citations

Purification and biochemical properties of a high-molecular-mass inositol 1,4,5-trisphosphate 3-kinase isoenzyme in human platelets

1994 • 30 citations

Calmodulin concentrated at the osteoclast ruffled border modulates acid secretion

1994 • 29 citations

Increased calmodulin affects cell morphology and mRNA levels of cytoskeletal protein genes

1992 • 17 citations