Deficient Anti-Listerial Immunity in the Absence of Perforin Can Be Restored by Increasing Memory CD8+ T Cell Numbers

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1999 • 5,659 citations

Preferential Localization of Effector Memory Cells in Nonlymphoid Tissue

2001 • 1,922 citations

Lineage relationship and protective immunity of memory CD8 T cell subsets

2003 • 1,833 citations

Comparative Genomics of Listeria Species

2001 • 1,491 citations

Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways

1994 • 1,073 citations

CD8+ T Cell Effector Mechanisms in Resistance to Infection

2000 • 725 citations

Programmed contraction of CD8+ T cells after infection

2002 • 586 citations

Coordinate Regulation of Complex T Cell Populations Responding to Bacterial Infection

1998 • 535 citations

Immune function in mice lacking the perforin gene.

1994 • 474 citations

Regulation of Antigen-Specific CD8 ⁺ T Cell Homeostasis by Perforin and Interferon-γ

2000 • 452 citations

Specific immunity to listeria monocytogenes in the absence of IFNγ

1995 • 432 citations

Precise prediction of a dominant class I MHC-restricted epitope of Listeria monocytogenes

1991 • 425 citations

T Cell Affinity Maturation by Selective Expansion during Infection

1999 • 420 citations

What messenger RNA capping tells us about eukaryotic evolution

2002 • 351 citations

Functional avidity maturation of CD8+ T cells without selection of higher affinity TCR

2001 • 349 citations

Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes

1994 • 307 citations

Priming of Memory But Not Effector CD8 T Cells by a Killed Bacterial Vaccine

2001 • 294 citations

Studies with MHC-deficient knock-out mice reveal impact of both MHC I- and MHC II-dependent T cell responses on listeria monocytogenes infection

1995 • 244 citations

Progression of Armed CTL from Draining Lymph Node to Spleen Shortly After Localized Infection with Herpes Simplex Virus 1

2002 • 231 citations

CD8+ T cell-mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity

1994 • 229 citations

Compartmentalization of Bacterial Antigens: Differential Effects on Priming of CD8 T Cells and Protective Immunity

1998 • 228 citations

Reversible MHC multimer staining for functional isolation of T-cell populations and effective adoptive transfer

2002 • 210 citations

Studies with MHC-deficient knock-out mice reveal impact of both MHC I- and MHC II-dependent T cell responses on Listeria monocytogenes infection.

1994 • 201 citations

Evolution of the T Cell Repertoire During Primary, Memory, and Recall Responses to Viral Infection

2000 • 150 citations

Identification of an H2-M3-Restricted Listeria Epitope: Implications for Antigen Presentation by M3

1996 • 148 citations

Immunodominant and subdominant CTL responses to Listeria monocytogenes infection.

1997 • 146 citations

Listeriosis in p47phox−/− and TRp55−/− Mice: Protection Despite Absence of ROI and Susceptibility Despite Presence of RNI

1997 • 130 citations

Role of T Cell Subsets in Immunity against Intracellular Bacteria: Experimental Infections of Knock-Out Mice with Listeria monocytogenes and Mycobacterium bovis BCG

1994 • 127 citations

Viral Infection Results in Massive CD8+ T Cell Expansion and Mortality in Vaccinated Perforin-Deficient Mice

2003 • 120 citations

Regulation of CD8+ T Cells Undergoing Primary and Secondary Responses to Infection in the Same Host

2003 • 111 citations

CD8 T lymphocytes specific for the secreted p60 antigen protect against Listeria monocytogenes infection.

1995 • 105 citations

Listeria monocytogenes infection in beta 2 microglobulin-deficient mice

1993 • 100 citations

Intracellular staining for TNF and IFN-γ detects different frequencies of antigen-specific CD8+ T cells

2000 • 99 citations

Perforin-deficient CD8+ T cells provide immunity to Listeria monocytogenes by a mechanism that is independent of CD95 and IFN-gamma but requires TNF-alpha.

1998 • 93 citations

Perforin-Deficient CD8+ T Cells Provide Immunity to Listeria monocytogenes by a Mechanism That Is Independent of CD95 and IFN-γ but Requires TNF-α

1998 • 83 citations

Intestinal and Splenic T Cell Responses to EntericListeria monocytogenesInfection: Distinct Repertoires of Responding CD8 T Lymphocytes

2001 • 67 citations

Fas (CD95)-Dependent Cell-Mediated Immunity to Listeria monocytogenes

1998 • 60 citations

Mice Deficient in Perforin, CD4⁺T Cells, or CD28-Mediated Signaling Maintain the Typical Immunodominance Hierarchies of CD8⁺T-Cell Responses to Influenza Virus

2002 • 58 citations

Perforin-Deficient CD8+ T Cells: In Vivo Priming and Antigen-Specific Immunity AgainstListeria monocytogenes

1999 • 57 citations

Listeria monocytogenes as a probe to study cell-mediated immunity

1998 • 52 citations

Quantitation of CD8+ T Cell Expansion, Memory, and Protective Immunity After Immunization with Peptide-Coated Dendritic Cells

2002 • 50 citations

Cutting Edge: Antilisterial Activity of CD8+ T Cells Derived from TNF-Deficient and TNF/Perforin Double-Deficient Mice

2000 • 50 citations

A nonamer peptide derived from Listeria monocytogenes metalloprotease is presented to cytolytic T lymphocytes

1997 • 45 citations

Perforin-Mediated CTL Cytolysis Counteracts Direct Cell-Cell Spread of Listeria monocytogenes

2002 • 40 citations

A Knockout Approach to Understanding CD8+ Cell Effector Mechanisms in Adaptive Immunity to Listeria Monocytogenes

1999 • 20 citations

CD8⁺T-Cell Priming against a NonsecretedListeria monocytogenesAntigen Is Independent of the Antimicrobial Activities of Gamma Interferon

2000 • 18 citations