Endogenous Retinoid X Receptors Can Function as Hormone Receptors in Pituitary Cells

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Current protocols in molecular biology

1988 • 7,584 citations

A human retinoic acid receptor which belongs to the family of nuclear receptors

1987 • 2,245 citations

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

1992 • 1,790 citations

Nuclear receptor that identifies a novel retinoic acid response pathway

1990 • 1,529 citations

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

1992 • 1,514 citations

RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1991 • 1,241 citations

Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.

1992 • 1,200 citations

Nuclear receptors enhance our understanding of transcription regulation

1988 • 1,062 citations

Identification of a second human retinoic acid receptor

1988 • 1,049 citations

Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors

1992 • 966 citations

Identification and spatial distribution of retinoids in the developing chick limb bud

1987 • 964 citations

Cloning and expression of full-length cDNA encoding human vitamin D receptor.

1988 • 961 citations

Role of retinoids in differentiation and carcinogenesis.

1983 • 780 citations

Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids.

1993 • 738 citations

A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR

1991 • 672 citations

RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis.

1994 • 632 citations

Retinoic acid and thyroid hormone induce gene expression through a common responsive element

1988 • 586 citations

Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid

1992 • 583 citations

Vitamin A and Retinoids in Health and Disease

1984 • 560 citations

Two nuclear signalling pathways for vitamin D

1993 • 559 citations

Characterization of an autoregulated response element in the mouse retinoic acid receptor type beta gene.

1990 • 487 citations

Molecular Basis of Thyroid Hormone Action

1983 • 434 citations

Sequence elements in the human osteocalcin gene confer basal activation and inducible response to hormonal vitamin D3.

1989 • 409 citations

Differential expression and ligand regulation of the retinoic acid receptor alpha and beta genes.

1989 • 403 citations

Hormone and antihormone induce distinct conformational changes which are central to steroid receptor activation.

1992 • 363 citations

A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone

1987 • 347 citations

Retinoids Selective for Retinoid X Receptor Response Pathways

1992 • 342 citations

Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors

1992 • 341 citations

DNA sequences in the rat osteocalcin gene that bind the 1,25-dihydroxyvitamin D3 receptor and confer responsiveness to 1,25-dihydroxyvitamin D3.

1990 • 322 citations

Regulation of gene expression by thyroid hormone.

1988 • 317 citations

Growth hormone gene transcription is regulated by thyroid and glucocorticoid hormones in cultured rat pituitary tumor cells.

1982 • 280 citations

Hormonal regulation of the growth hormone gene. Relationship of the rate of transcription to the level of nuclear thyroid hormone-receptor complexes.

1984 • 259 citations

Retinoic acid regulates growth hormone gene expression

1989 • 240 citations

Mutations of the Rat Growth Hormone Promoter which Increase and Decrease Response to Thyroid Hormone Define a Consensus Thyroid Hormone Response Element

1989 • 240 citations

Identification of Nuclear Factors that Enhance Binding of the Thyroid Hormone Receptor to a Thyroid Hormone Response Element

1989 • 219 citations

The patterns of binding of RAR, RXR and TR homo- and heterodimers to direct repeats are dictated by the binding specificites of the DNA binding domains.

1993 • 218 citations

A retinoic acid-responsive element in the apolipoprotein AI gene distinguishes between two different retinoic acid response pathways.

1991 • 217 citations

Multiple cell type-specific proteins differentially regulate target sequence recognition by the α retinoic acid receptor

1990 • 211 citations

Vitamin D receptor interaction with specific DNA requires a nuclear protein and 1,25-dihydroxyvitamin D3.

1990 • 197 citations

Functional inhibition of retinoic acid response by dominant negative retinoic acid receptor mutants.

1993 • 193 citations

Transactivation properties of retinoic acid and retinoid X receptors in mammalian cells and yeast. Correlation with hormone binding and effects of metabolism.

1993 • 185 citations

Functional characterization of the rat growth hormone promoter elements required for induction by thyroid hormone with and without a co-transfected β type thyroid hormone receptor

1989 • 177 citations

Cyclic AMP analogs and retinoic acid influence the expression of retinoic acid receptor alpha, beta, and gamma mRNAs in F9 teratocarcinoma cells.

1990 • 173 citations

Molecular Biology of the Vitamin D Hormone

1988 • 167 citations

Differential DNA binding by monomeric, homodimeric, and potentially heteromeric forms of the thyroid hormone receptor.

1991 • 163 citations

Loss of retinoic acid receptor gamma function in F9 cells by gene disruption results in aberrant Hoxa-1 expression and differentiation upon retinoic acid treatment.

1993 • 143 citations

Heterodimerization among thyroid hormone receptor, retinoic acid receptor, retinoid X receptor, chicken ovalbumin upstream promoter transcription factor, and an endogenous liver protein.

1992 • 137 citations

3,5,3′-Triiodothyronine (T₃) Receptor-Auxiliary Protein (TRAP) Binds DNA and Forms Heterodimers with the T₃Receptor

1991 • 130 citations

Different agonist- and antagonist-induced conformational changes in retinoic acid receptors analyzed by protease mapping.

1994 • 125 citations

The Nuclear Receptor–Triiodothyronine Complex: Relationship to Thyroid Hormone Distribution, Metabolism, and Biological Action

1983 • 119 citations

Dominant negative activity of an endogenous thyroid hormone receptor variant (alpha 2) is due to competition for binding sites on target genes.

1993 • 118 citations

Characterization of DNA binding and retinoic acid binding properties of retinoic acid receptor.

1991 • 114 citations

Functional characterization of a natural retinoic acid responsive element.

1991 • 100 citations

Formation of retinoid X receptor homodimers leads to repression of T3 response: hormonal cross talk by ligand-induced squelching.

1993 • 99 citations

Thyroid Hormone Receptor Mutations that Interfere with Transcriptional Activation also Interfere with Receptor Interaction with a Nuclear Protein

1991 • 93 citations

Multihormonal Regulation of the Human, Rat, and Bovine Growth Hormone Promoters: Differential Effects of 3′,5′-Cyclic Adenosine Monophosphate, Thyroid Hormone, and Glucocorticoids

1988 • 92 citations

The Family of Retinoic Acid Nuclear Receptors

2015 • 85 citations

Efficient transactivation by retinoic acid receptors in yeast requires retinoid X receptors.

1993 • 84 citations

Reconstitution of retinoid X receptor function and combinatorial regulation of other nuclear hormone receptors in the yeast Saccharomyces cerevisiae.

1993 • 67 citations

Ligand-dependent synergy of thyroid hormone and retinoid X receptors.

1992 • 53 citations

Selective antagonism of thyroid hormone action by retinoic acid.

1992 • 38 citations

9-cis-retinoic acid regulates the expression of the muscle determination gene Myf5.

1993 • 29 citations

Induction of retinoic acid receptor-beta by retinoic acid is cell specific.

1993 • 27 citations

Deleted Work

1955 • 0 citations