Regulation of the Double-stranded RNA-Dependent Protein Kinase PKR by RNAs Encoded by a Repeated Sequence in the Epstein-Barr Virus Genome

Structural features in eukaryotic mRNAs that modulate the initiation of translation.

1991 • 1,849 citations

Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product

1987 • 902 citations

Phosphorylation of initiation factor eIF-2 and the control of reticulocyte protein synthesis

1977 • 750 citations

Nucleic acid structure and expression of the human AIDS/lymphadenopathy retrovirus

1985 • 706 citations

Circumstances and mechanisms of inhibition of translation by secondary structure in eucaryotic mRNAs.

1989 • 618 citations

Interactions between double-stranded RNA regulators and the protein kinase DAI.

1992 • 475 citations

Adenovirus virus-associated RNA and translation control

1991 • 387 citations

The eIF-2 alpha protein kinases, regulators of translation in eukaryotes from yeasts to humans.

1993 • 383 citations

Transcription and translation : a Practical Approach

1984 • 375 citations

Early events in Epstein-Barr virus infection of human B lymphocytes

1991 • 297 citations

The characteristics of inhibition of protein synthesis by double-stranded ribonucleic acid in reticulocyte lysates

1975 • 254 citations

Two RNA-binding motifs in the double-stranded RNA-activated protein kinase, DAI.

1992 • 243 citations

Circumstances and Mechanisms of Inhibition of Translation by Secondary Structure in Eucaryotic mRNAs

1989 • 238 citations

Purification and activation of the double-stranded RNA-dependent eIF-2 kinase DAI.

1989 • 197 citations

Promoter switching in Epstein-Barr virus during the initial stages of infection of B lymphocytes.

1990 • 196 citations

Comparative analysis of the regulation of the interferoninducible protein kinase PKR by Epstein - Barr virus RNAs EBER-1 and EBER-2 and adenovirus VA, RNA

1993 • 175 citations

Binding of Epstein-Barr virus small RNA EBER-1 to the double-stranded RNA-activated protein kinase DAI

1991 • 162 citations

Preparative in vitro mRNA synthesis using SP6 and T7 RNA polymerases

1991 • 155 citations

Restricted Epstein-Barr virus protein expression in Burkitt lymphoma is due to a different Epstein-Barr nuclear antigen 1 transcriptional initiation site.

1991 • 153 citations

Interactions between Double-Stranded RNA Regulators and the Protein Kinase DAI

1992 • 151 citations

Redefining the Epstein-Barr virus-encoded nuclear antigen EBNA-1 gene promoter and transcription initiation site in group I Burkitt lymphoma cell lines.

1995 • 150 citations

The binding of double-stranded RNA and adenovirus VAI RNA to the interferon-induced protein kinase

1989 • 143 citations

HIV-1 TAR RNA Has an Intrinsic Ability to Activate Interferon-Inducible Enzymes

1994 • 142 citations

Activation of interferon-regulated, dsRNA-dependent enzymes by human immunodeficiency virus-1 leader RNA

1989 • 135 citations

Tat-responsive region RNA of human immunodeficiency virus 1 can prevent activation of the double-stranded-RNA-activated protein kinase.

1990 • 131 citations

Epstein-Barr Virus Latent Gene Expression during the Initiation of B Cell Immortalization

1989 • 127 citations

Binding properties of newly identified Xenopus proteins containing dsRNA-binding motifs

1994 • 125 citations

Mutually exclusive use of viral promoters in Epstein-Barr virus latently infected lymphocytes.

1989 • 122 citations

A promoter for the highly spliced EBNA family of RNAs of Epstein-Barr virus

1987 • 122 citations

Nucleotide sequence of genes coding for tRNAPhe and tRNATyr from a repeating unit of X. laevis DNA

1980 • 115 citations

The integrity of the stem structure of human immunodeficiency virus type 1 Tat-responsive sequence of RNA is required for interaction with the interferon-induced 68,000-Mr protein kinase

1991 • 111 citations

Exclusive expression of Epstein-Barr virus nuclear antigen 1 in Burkitt lymphoma arises from a third promoter, distinct from the promoters used in latently infected lymphocytes.

1991 • 109 citations

Functional Characterization of the RNA-binding Domain and Motif of the Double-stranded RNA-dependent Protein Kinase DAI (PKR)

1995 • 105 citations

The guanine nucleotide-exchange factor, eIF-2B

1994 • 101 citations

Epstein-Barr virus mRNAs produced by alternative splicing

1986 • 100 citations

Mechanism of interferon action activation of the human P1/eIF-2α protein kinase by individual reovirus s-class mRNAs: s1 mRNA is a potent activator relative to s4 mRNA

1989 • 92 citations

Translational control by the Epstein‐Barr virus small RNA EBER‐1

1990 • 84 citations

Spliced RNA from the IR1-U2 region of Epstein-Barr virus: presence of an open reading frame for a repetitive polypeptide.

1984 • 82 citations

Inhibition of translation in cells infected with a poliovirus 2Apro mutant correlates with phosphorylation of the alpha subunit of eucaryotic initiation factor 2

1989 • 80 citations

Modification of protein synthesis initiation factors and the shut-off of host protein synthesis in adenovirus-infected cells

1989 • 80 citations

Tat-responsive region RNA of human immunodeficiency virus type 1 stimulates protein synthesis in vivo and in vitro: relationship between structure and function.

1992 • 67 citations

Human immunodeficiency virus type 1 transactivator protein, tat, stimulates transcriptional read-through of distal terminator sequences in vitro.

1993 • 65 citations

Removal of double-stranded contaminants from RNA transcripts: synthesis of adenovirus VA RNA₁from a T7 vector

1990 • 65 citations

Purification and Activation of the Double-Stranded RNA-Dependent eIF-2 Kinase DAI

1989 • 64 citations

Alternative splicing dictates translational start in Epstein-Barr virus transcripts.

1990 • 58 citations

Paradoxical interactions between human delta hepatitis agent RNA and the cellular protein kinase PKR

1996 • 56 citations

Detection of protein kinase homologues and viral RNA-binding domains utilizing polyclonal antiserum prepared against a baculovirus-expressed ds RNA-activated 68,000-Da protein kinase

1992 • 53 citations

Identification of a Novel Promoter Located Within theBamHI Q Region of the Epstein-Barr Virus Genome for the EBNA 1 Gene

1995 • 48 citations

Reversal of the double‐stranded‐RNA‐induced inhibition of protein synthesis by a catalytically inactive mutant of the protein kinase PKR

1993 • 38 citations

Epstein-Barr Virus In B Lymphocytes: Viral Gene Expression and Function in Latency

1992 • 33 citations

Viral and Cellular Factors Influence the Activity of the Epstein-Barr Virus BCR2 and BWR1 Promoters in Cells of Different Phenotype

1993 • 27 citations

Epstein-Barr virus gene expression in interferon-treated cells

1990 • 24 citations

Transcriptional and translational events during reovirus infection

1988 • 18 citations

Inhibition of Epstein-Barr virus infection in vitro by recombinant human interferons α and γ

1986 • 17 citations

Repression of Vertebrate RNA Polymerase III Transcription by DNA Binding Proteins Located Upstream from the Transcription Start Site

1995 • 16 citations

Latent infection of B lymphocytes by Epstein-Barr virus

1994 • 15 citations

Mechanism of interferon action. Translational control and the RNA-dependent protein kinase (PKR): antagonists of PKR enhance the translational activity of mRNAs that include a 161 nucleotide region from reovirus S1 mRNA.

1994 • 14 citations