Interactions between Double-Stranded RNA Regulators and the Protein Kinase DAI

INTERFERONS AND THEIR ACTIONS

1987 • 1,838 citations

TRANSLATIONAL CONTROL IN MAMMALIAN CELLS

1991 • 1,041 citations

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

1990 • 1,003 citations

Phosphorylation of initiation factor 2α by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

1992 • 768 citations

Phosphorylation of initiation factor eIF-2 and the control of reticulocyte protein synthesis

1977 • 750 citations

ompT encodes the Escherichia coli outer membrane protease that cleaves T7 RNA polymerase during purification

1988 • 673 citations

Antiviral actions of interferon interferon-regulated cellular proteins and their surprisingly selective antiviral activities

1991 • 600 citations

Adenovirus virus-associated RNA and translation control

1991 • 387 citations

Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2α kinase

1986 • 358 citations

Interferon, double-stranded RNA, and protein phosphorylation.

1976 • 328 citations

Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator GCN2.

1992 • 325 citations

Protein Phosphorylation Controls Translation Rates

1989 • 303 citations

Autophosphorylation of the protein kinase dependent on double-stranded RNA.

1987 • 301 citations

Structural requirements of double-stranded RNA for the activation of 2‘,5‘-oligo(A) polymerase and protein kinase of interferon-treated HeLa cells.

1979 • 263 citations

A mechanism for the control of protein synthesis by adenovirus VA RNAI

1986 • 256 citations

The characteristics of inhibition of protein synthesis by double-stranded ribonucleic acid in reticulocyte lysates

1975 • 254 citations

2-Aminopurine Selectively Inhibits the Induction of β-Interferon, c- fos , and c- myc Gene Expression

1988 • 233 citations

Regulation of protein synthesis initiation in eucaryotes

1983 • 227 citations

Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr protein kinase in a cell-free system.

1991 • 207 citations

Regulation of protein synthesis: Activation by double-stranded RNA of a protein kinase that phosphorylates eukaryotic initiation factor 2

1978 • 206 citations

The Double Stranded RNA-Activated Protein Kinase Induced by Interferon: dsRNA-PK

1989 • 202 citations

Isolation of two interferon-induced translational inhibitors: a protein kinase and an oligo-isoadenylate synthetase.

1978 • 194 citations

IMPACT OF VIRUS INFECTION ON HOST CELL PROTEIN SYNTHESIS

1987 • 188 citations

Identification of double-stranded RNA-binding domains in the interferon-induced double-stranded RNA-activated p68 kinase.

1992 • 176 citations

Mechanism of interferon action: Identification of a RNA binding domain within the N-terminal region of the human RNA-dependent P1/eIF-2α protein kinase

1992 • 170 citations

The binding of double-stranded RNA and adenovirus VAI RNA to the interferon-induced protein kinase

1989 • 143 citations

Monoclonal antibodies to an interferon-induced Mr 68,000 protein and their use for the detection of double-stranded RNA-dependent protein kinase in human cells.

1985 • 138 citations

Tat-responsive region RNA of human immunodeficiency virus 1 can prevent activation of the double-stranded-RNA-activated protein kinase.

1990 • 131 citations

Interferon, double-stranded RNA, and protein phosphorylation. Characteristics of a double-stranded RNA-activated protein kinase system partially purified from interferon treated Ehrlich ascites tumor cells.

1978 • 128 citations

Identification of the double-stranded RNA-binding domain of the human interferon-inducible protein kinase.

1992 • 121 citations

Inhibition of mRNA binding to ribosomes by localized activation of dsRNA-dependent protein kinase

1984 • 100 citations

Characterization of double-stranded-RNA-activated kinase that phosphorylates α subunit of eukaryotic initiation factor 2 (eIF-2α) in reticulocyte lysates

1980 • 93 citations

Interaction of adenovirus VA RNAI with the protein kinase DAI: Nonequivalence of binding and function

1990 • 93 citations

Mechanism of interferon action activation of the human P1/eIF-2α protein kinase by individual reovirus s-class mRNAs: s1 mRNA is a potent activator relative to s4 mRNA

1989 • 92 citations

Growth-related expression of a double-stranded RNA-dependent protein kinase in 3T3 cells.

1984 • 91 citations

Translational control by the Epstein‐Barr virus small RNA EBER‐1

1990 • 84 citations

The interferon-induced protein kinase PK-i from mouse L cells.

1979 • 81 citations

Modification of protein synthesis initiation factors and the shut-off of host protein synthesis in adenovirus-infected cells

1989 • 80 citations

Construction and analysis of additional adenovirus substitution mutants confirm the complementation of VAI RNA function by two small RNAs encoded by Epstein-Barr virus

1985 • 79 citations

Mechanism of interferon action. Purification and substrate specificities of the double-stranded RNA-dependent protein kinase from untreated and interferon-treated mouse fibroblasts.

1985 • 78 citations

Effects of mutations in stem and loop regions on the structure and function of adenovirus VA RNAI.

1988 • 78 citations

Two interferon-induced proteins are involved in the protein kinase complex dependent on double-stranded RNA

1985 • 78 citations

Adenovirus VA RNAI mediates a translational stimulation which is not restricted to the viral mRNAs.

1985 • 77 citations

Removal of double-stranded contaminants from RNA transcripts: synthesis of adenovirus VA RNA₁from a T7 vector

1990 • 65 citations

Purification and Activation of the Double-Stranded RNA-Dependent eIF-2 Kinase DAI

1989 • 64 citations

Mechanism of interferon action. Characterization of sites of phosphorylation in the interferon-induced phosphoprotein P1 from mouse fibroblasts: evidence for two forms of P1.

1982 • 59 citations

Inhibition of protein synthesis by double-stranded RNA and phosphorylation of initiation factor, eIF-2.

1978 • 55 citations

Activation of 2',5'-oligo(A) polymerase and protein kinase of interferon-treated HeLa cells by 2'-O-methylated poly (inosinic acid) . poly(cytidylic acid), Correlations with interferon-inducing activity.

1980 • 47 citations

Gene Induction by Interferons and Double-Stranded RNA: Selective Inhibition by 2-Aminopurine

1988 • 41 citations

Identification of a 90-kDa polypeptide which associates with adenovirus VA RNAI and is phosphorylated by the double-stranded RNA-dependent protein kinase

1989 • 36 citations

Structural requirements of polynucleotides for the activation of (2′-5′)A_npolymerase and protein kinase

1981 • 36 citations

Control of Translation in Adenovirus-Infected Cells

1990 • 35 citations

Reduced Activity of the Interferon-induced Double-stranded RNA-dependent Protein Kinase during a Heat Shock Stress

1989 • 35 citations

Translational Control by Influenza Virus: Suppression of the Kinase That Phosphorylates the Alpha Subunit of Initiation Factor eIF-2 and Selective Translation of Influenza Viral mRNAs

1986 • 30 citations

Activation of human and mouse 2‐5A synthetases and mouse protein P₁ kinase by nucleic acids

1981 • 28 citations

Inhibition of double-stranded ribonucleic acid activated protein kinase and 2',5'-oligo(adenylic acid) polymerase by ethidium bromide

1981 • 14 citations

Translational Control Mediated by Eucaryotic Initiation Factor-2 Is Restricted to Specific mRNAs in Transfected Cells

1987 • 14 citations