Folding of a nascent polypeptide chain in vitro: cooperative formation of structure in a protein module.

Principles that Govern the Folding of Protein Chains

1973 • 6,771 citations

Calculation of protein extinction coefficients from amino acid sequence data

1989 • 5,198 citations

Protein folding in the cell

1992 • 4,138 citations

Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins

1983 • 3,150 citations

Circular dichroic analysis of protein conformation: Inclusion of the β-turns

1978 • 1,088 citations

Successive action of DnaK, DnaJ and GroEL along the pathway of chaperone-mediated protein folding

1992 • 965 citations

Proteins as molecular chaperones

1987 • 910 citations

Folding of chymotrypsin inhibitor 2. 1. Evidence for a two-state transition

1991 • 882 citations

Determination of protein secondary structure in solution by vacuum ultraviolet circular dichroism

1980 • 777 citations

Folding of nascent polypeptide chains in a high molecular mass assembly with molecular chaperones

1994 • 651 citations

Secondary Structure of Proteins Through Circular Dichroism Spectroscopy

1988 • 537 citations

Protein folding: local structures, domains, subunits, and assemblies

1991 • 432 citations

Molecular chaperones in protein folding: the art of avoiding sticky situations

1994 • 402 citations

Quantitative Determination of Helical Propensities from Trifluoroethanol Titration Curves

1994 • 323 citations

Crystal and molecular structure of the serine proteinase inhibitor CI-2 from barley seeds

1987 • 260 citations

Characterization of the transition state of protein unfolding by use of molecular dynamics: chymotrypsin inhibitor 2.

1994 • 245 citations

Protein folding and stability: the pathway of folding of barnase

1993 • 242 citations

Structure of the transition state for the folding/unfolding of the barley chymotrypsin inhibitor 2 and its implications for mechanisms of protein folding.

1994 • 218 citations

Folding of chymotrypsin inhibitor 2. 2. Influence of proline isomerization on the folding kinetics and thermodynamic characterization of the transition state of folding

1991 • 204 citations

Structure of the hydrophobic core in the transition state for folding of chymotrypsin inhibitor 2: A critical test of the protein engineering method of analysis

1993 • 141 citations

An N-terminal fragment of barnase has residual helical structure similar to that in a refolding intermediate

1992 • 92 citations

Direct observation of better hydration at the N terminus of an alpha-helix with glycine rather than alanine as the N-cap residue.

1994 • 77 citations

Dissection of an enzyme by protein engineering

1992 • 72 citations

Refinement of the three-dimensional solution structure of barley serine proteinase inhibitor 2 and comparison with the structures in crystals

1991 • 69 citations

Folding of the nascent peptide chain into a biologically active protein

1988 • 64 citations

Generation of a Family of Protein Fragments for Structure-Folding Studies. 1. Folding Complementation of Two Fragments of Chymotrypsin Inhibitor-2 Formed by Cleavage at Its Unique Methionine Residue

1994 • 56 citations

Protein anatomy: functional roles of barnase module.

1993 • 48 citations

In vitro and ribosome-bound folding intermediates of P22 tailspike protein detected with monoclonal antibodies.

1994 • 39 citations

The structure of the transition state for the association of two fragments of the barley chymotrypsin inhibitor 2 to generate native-like protein: implications for mechanisms of protein folding.

1994 • 38 citations

Conformation in Biology and Drug Design

1985 • 21 citations