Folding of chymotrypsin inhibitor 2. 2. Influence of proline isomerization on the folding kinetics and thermodynamic characterization of the transition state of folding

Stability of Proteins Small Globular Proteins

1979 • 2,139 citations

Stability of Protein Structure and Hydrophobic Interaction

1988 • 1,293 citations

INTERMEDIATES IN THE FOLDING REACTIONS OF SMALL PROTEINS

1990 • 1,133 citations

Consideration of the possibility that the slow step in protein denaturation reactions is due to cis-trans isomerism of proline residues

1975 • 1,108 citations

Specific Intermediates in the Folding Reactions of Small Proteins and the Mechanism of Protein Folding

1982 • 1,041 citations

Acid-induced folding of proteins.

1990 • 555 citations

Catalysis of protein folding by prolyl isomerase

1987 • 488 citations

The mechanism of protein folding. Implications of in vitro refolding models for de novo protein folding and translocation in the cell

1990 • 372 citations

Nmr studies of the rates of proline cis–trans isomerization in oligopeptides

1981 • 368 citations

The X‐Pro peptide bond as an nmr probe for conformational studies of flexible linear peptides

1976 • 270 citations

Crystal and molecular structure of the serine proteinase inhibitor CI-2 from barley seeds

1987 • 260 citations

Cloning, expression, and purification of human cyclophilin in Escherichia coli and assessment of the catalytic role of cysteines by site-directed mutagenesis.

1990 • 247 citations

Nuclear Magnetic Resonance Study of the Protolysis and Ionization of N-Methylacetamide¹

1959 • 228 citations

Low-temperature unfolding of a mutant of phage T4 lysozyme. 2. Kinetic investigations

1989 • 161 citations

Folding of ribonuclease T1. 1. Existence of multiple unfolded states created by proline isomerization

1990 • 150 citations

Characterization of the transition state of Lysozyme unfolding. I. Effect of protein‐solvent interactions on the transition state

1984 • 149 citations

Folding of ribonuclease T1. 2. Kinetic models for the folding and unfolding reactions

1990 • 141 citations

Cis‐Trans equilibrium and kinetic studies of acetyl‐<scp>L</scp>‐proline and glycyl‐<scp>L</scp>‐proline

1977 • 138 citations

Test of the extended two-state model for the kinetic intermediates observed in the folding transition of ribonuclease A

1978 • 137 citations

Nmr studies of the molecular conformations in the linear oligopeptides H‐(<scp>L</scp>‐Ala)_n‐<scp>L</scp>‐Pro‐OH

1976 • 129 citations

Replacement of a cis proline simplifies the mechanism of ribonuclease T1 folding

1990 • 129 citations

Einfache Temperatursprung-Methode im Sekundenbis Stundenbereich und die reversible Denaturierung von Chymotrypsin

1968 • 92 citations

Recombinant chymotrypsin inhibitor 2: expression, kinetic analysis of inhibition with .alpha.-chymotrypsin and wild-type and mutant subtilisin BPN', and protein engineering to investigate inhibitory specificity and mechanism

1990 • 79 citations

Catalysis of proline isomerization during protein-folding reactions

1988 • 73 citations

The rate of interconversion between the two unfolded forms of ribonuclease A does not depend on guanidinium chloride concentration

1979 • 71 citations

Comparison of the solution and X-ray structures of barley serine proteinase inhibitor 2

1987 • 64 citations

The determination of the three-dimensional structure of barley serine proteinase inhibitor 2 by nuclear magnetic resonance, distance geometry and restrained molecular dynamics

1987 • 58 citations

Two slow stages in refolding of bovine carbonic anhydrase B are due to proline isomerization

1990 • 51 citations