Fine mapping of a multiple sclerosis locus to 2.5 Mb on chromosome 17q22-q24

The Sequence of the Human Genome

2001 • 13,500 citations

New diagnostic criteria for multiple sclerosis: Guidelines for research protocols

1983 • 7,404 citations

Axonal Transection in the Lesions of Multiple Sclerosis

1998 • 4,007 citations

de la Chapelle, A.

1997 • 3,184 citations

Parametric and nonparametric linkage analysis: a unified multipoint approach.

1996 • 2,905 citations

PedCheck: A Program for Identification of Genotype Incompatibilities in Linkage Analysis

1998 • 2,089 citations

Easy calculations of lod scores and genetic risks on small computers.

1984 • 1,526 citations

Faster sequential genetic linkage computations.

1993 • 1,378 citations

Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics.

1996 • 1,201 citations

A twin-pronged attack on complex traits

1997 • 695 citations

Avoiding Recomputation in Linkage Analysis

1994 • 679 citations

A full genome search in multiple sclerosis

1996 • 666 citations

BACH1, a Novel Helicase-like Protein, Interacts Directly with BRCA1 and Contributes to Its DNA Repair Function

2001 • 655 citations

A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex

1996 • 650 citations

A Population-Based Study of Multiple Sclerosis in Twins

1986 • 644 citations

A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22

1996 • 638 citations

A genetic basis for familial aggregation in multiple sclerosis

1995 • 626 citations

The epidemiology of multiple sclerosis

2016 • 505 citations

A Haplotype-Based Haplotype Relative Risk’ Approach to Detecting Allelic Associations

1992 • 502 citations

Molecular genetics of the Finnishdisease heritage

1999 • 492 citations

Use of population isolates for mapping complex traits

2000 • 449 citations

A population‐based study of multiple sclerosis in twins: Update

1993 • 420 citations

Disease gene mapping in isolated human populations: the example of Finland.

1993 • 368 citations

Detection and Integration of Genotyping Errors in Statistical Genetics

2002 • 359 citations

Evidence for genetic basis of multiple sclerosis

1996 • 355 citations

Genomewide Scan of Multiple Sclerosis in Finnish Multiplex Families

1997 • 308 citations

Immunohistochemical and genetic evidence of myeloperoxidase involvement in multiple sclerosis

1997 • 284 citations

Mutations in the protein kinase A R1α regulatory subunit cause familial cardiac myxomas and Carney complex

2000 • 274 citations

Analysis of gene expression in multiple sclerosis lesions using cDNA microarrays

1999 • 245 citations

Identification of a Novel Genetic Locus for Familial Cardiac Myxomas and Carney Complex

1998 • 219 citations

Closing in on a breast cancer gene on chromosome 17q.

1992 • 217 citations

The pathology of multiple sclerosis

2005 • 210 citations

A putative vulnerability locus to multiple sclerosis maps to 5p14–p12 in a region syntenic to the murine locus Eae2

1996 • 209 citations

Linkage Analysis in the Presence of Errors IV: Joint Pseudomarker Analysis of Linkage and/or Linkage Disequilibrium on a Mixture of Pedigrees and Singletons When the Mode of Inheritance Cannot Be Accurately Specified

2000 • 187 citations

Gene encoding a new RING-B-box-Coiled-coil protein is mutated in mulibrey nanism

2000 • 177 citations

The genetics of multiple sclerosis: principles, background and updated results of the United Kingdom systematic genome screen

1998 • 173 citations

New Genetic Loci That Control Susceptibility and Symptoms of Experimental Allergic Encephalomyelitis in Inbred Mice

1998 • 151 citations

AXONAL TRANSECTION IN THE LESIONS OF MULTIPLE SCLEROSIS

1998 • 147 citations

Sensory neuron-specific sodium channel SNS is abnormally expressed in the brains of mice with experimental allergic encephalomyelitis and humans with multiple sclerosis

2000 • 126 citations

Localization of PS6K to chromosomal region 17q23 and determination of its amplification in breast cancer.

1999 • 99 citations

Increasing prevalence of multiple sclerosis in Finland

2001 • 92 citations

Sequence Polymorphisms in the Chemokines Scya1 (TCA-3), Scya2 (Monocyte Chemoattractant Protein (MCP)-1), and Scya12 (MCP-5) Are Candidates for eae7, a Locus Controlling Susceptibility to Monophasic Remitting/Nonrelapsing Experimental Allergic Encephalomyelitis

1999 • 80 citations

Mice lacking myeloperoxidase are more susceptible to experimental autoimmune encephalomyelitis

2001 • 78 citations

Regional and Temporal Variation in the Incidence of Multiple Sclerosis in Finland 1979–1993

2000 • 78 citations

Linkage disequilibrium in isolated populations: Finland and a young sub-population of Kuusamo

2000 • 77 citations

STUDIES ON THE CLUSTERING OF MULTIPLE SCLEROSIS IN FINLAND II: MICROEPIDEMIOLOGY IN ONE HIGH-RISK COUNTY WITH SPECIAL REFERENCE TO FAMILIAL CASES

1975 • 54 citations

Reappraisal of HLA in Multiple Sclerosis: Close Linkage in Multiplex Families

1993 • 49 citations

Genetic susceptibility to MS: a second stage analysis in Canadian MS families

2001 • 46 citations

Molecular cytogenetic analysis of consistent abnormalities at 8q12-q22 in breast cancer

1998 • 45 citations

A screen of candidates from peaks of linkage: evidence for the involvement of myeloperoxidase in multiple sclerosis

1999 • 43 citations

Mechanically stretched chromosomes as targets for high-resolution FISH mapping.

1995 • 43 citations

Golli-MBP gene in multiple sclerosis susceptibility

1998 • 41 citations

Envoplakin, a Possible Candidate Gene for Focal NEPPK/Esophageal Cancer (TOC): The Integration of Genetic and Physical Maps of the TOC Region on 17q25

1999 • 36 citations

Association of a myeloperoxidase promoter polymorphism with multiple sclerosis

2000 • 36 citations

Congenic mapping confirms a locus on rat chromosome 10 conferring strong protection against myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis

2001 • 36 citations

Epidemiology of Multiple Sclerosis

1984 • 35 citations

Assignment of the mulibrey nanism gene to 17q by linkage and linkage-disequilibrium analysis.

1997 • 30 citations

PECAM1, MPO and PRKAR1A at chromosome 17q21-q24 and susceptibility for multiple sclerosis in Sweden and Sardinia

2000 • 29 citations

High-Resolution Physical and Genetic Mapping of the Critical Region for Meckel Syndrome and Mulibrey Nanism on Chromosome 17q22–q23

1999 • 27 citations

Refinement of the RP17 locus for autosomal dominant retinitis pigmentosa, construction of a YAC contig and investigation of the candidate gene retinal fascin

1999 • 19 citations

Mapping the papillary renal cell carcinoma gene between loci D17S787 and D17S1799 on chromosome 17q21.32.

1999 • 14 citations

Studies on the clustering of multiple sclerosis in Finland.

1976 • 10 citations

Genetic susceptibility to multiple sclerosis linked to myelin basic protein gene

1993 • 6 citations

Mutations in the protein kinase A R1α regulatory subunit cause familial cardiac myxomas and Carney complex

2001 • 4 citations