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Constraints on reinitiation of translation in mammals

Data up to Jan 2025

Published2001
Citations287
References66

Total Citations Per Year

Abstract

References (66)

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

An analysis of vertebrate mRNA sequences: intimations of translational control.

1991 • 1,655 citations

Initiation of translation in prokaryotes and eukaryotes

1999 • 1,379 citations

Nonsense-mediated mRNA decayin health and disease

1999 • 974 citations

How do eucaryotic ribosomes select initiation regions in messenger RNA?

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Interpreting cDNA sequences: Some insights from studies on translation

1996 • 785 citations

Upstream Open Reading Frames as Regulators of mRNA Translation

2000 • 728 citations

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1989 • 618 citations

Effects of Intercistronic Length on the Efficiency of Reinitiation by Eucaryotic Ribosomes

1987 • 540 citations

Translational Regulation of Yeast GCN4

1997 • 533 citations

Recognition of AUG and alternative initiator codons is augmented by G in position +4 but is not generally affected by the nucleotides in positions +5 and +6

1997 • 486 citations

Context Effects and Inefficient Initiation at Non-AUG Codons in Eucaryotic Cell-Free Translation Systems

1989 • 471 citations

Regulation of Translation in Eukaryotic Systems

1992 • 467 citations

Translational control of C/EBP alpha and C/EBP beta isoform expression

2000 • 403 citations

An activating splice donor mutation in the thrombopoietin gene causes hereditary thrombocythaemia

1998 • 307 citations

Effects of intercistronic length on the efficiency of reinitiation by eucaryotic ribosomes.

1987 • 277 citations

Context effects and inefficient initiation at non-AUG codons in eucaryotic cell-free translation systems.

1989 • 272 citations

Adherence to the first-AUG rule when a second AUG codon follows closely upon the first.

1995 • 254 citations

Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational control.

1991 • 243 citations

Circumstances and Mechanisms of Inhibition of Translation by Secondary Structure in Eucaryotic mRNAs

1989 • 238 citations

Introduction of homologous DNA sequences into mammalian cells induces mutations in the cognate gene

1986 • 236 citations

Posttranscriptional Control of Gene Expression in Yeast

1998 • 225 citations

Ribosomal pausing during translation of an RNA pseudoknot.

1993 • 225 citations

Efficiency of reinitiation of translation on human immunodeficiency virus type 1 mRNAs is determined by the length of the upstream open reading frame and by intercistronic distance

1995 • 178 citations

Scanning model for translational reinitiation in eubacteria

1990 • 169 citations

Inhibition of translational initiation in the yeast Saccharomyces cerevisiae as a function of the stability and position of hairpin structures in the mRNA leader.

1993 • 136 citations

Effect of upstream reading frames on translation efficiency in simian virus 40 recombinants.

1986 • 125 citations

Effect of sequence context at stop codons on efficiency of reinitiation in GCN4 translational control

1994 • 115 citations

Role of two upstream open reading frames in the translational control of oncogene mdm2

1999 • 112 citations

Translational Control by an Upstream Open Reading Frame in the HER-2/neu Transcript

1999 • 110 citations

An internal open reading frame triggers nonsense-mediated decay of the yeast SPT10 mRNA

1999 • 105 citations

Ribosomal Pausing during Translation of an RNA Pseudoknot

1993 • 103 citations

The yeast transcription factor genes YAP1 and YAP2 are subject to differential control at the levels of both translation and mRNA stability

1998 • 96 citations

Features in the 5′ non-coding sequences of rabbit α and β-globin mRNAs that affect translational efficiency

1994 • 91 citations

Expression of Murine IL-12 Is Regulated by Translational Control of the p35 Subunit

1999 • 86 citations

Thrombopoietin Production Is Inhibited by a Translational Mechanism

1998 • 74 citations

Inefficient Reinitiation Is Responsible for Upstream Open Reading Frame–Mediated Translational Repression of the Maize R Gene

1998 • 74 citations

GCD10, a translational repressor of GCN4, is the RNA-binding subunit of eukaryotic translation initiation factor-3.

1995 • 73 citations

Effect of sequence context at stop codons on efficiency of reinitiation in GCN4 translational control.

1994 • 72 citations

Evaluation of the fidelity of initiation of translation in reticulocyte lysates from commercial sources

1990 • 71 citations

Primer extension analysis of eukaryotic ribosome-mRNA complexes

1998 • 68 citations

Biosynthesis of human fibroblast growth factor-5.

1991 • 68 citations

Effect of Upstream Reading Frames on Translation Efficiency in Simian Virus 40 Recombinants

1986 • 66 citations

Do the 5′Untranslated Domains of Human cDNAs Challenge the Rules for Initiation of Translation (or Is It Vice Versa)?

2000 • 60 citations

Translational inhibition by a human cytomegalovirus upstream open reading frame despite inefficient utilization of its AUG codon

1995 • 60 citations

Post-transcriptional Regulation of the GLI1 Oncogene by the Expression of Alternative 5′ Untranslated Regions

2001 • 52 citations

Complex organisation of the 5′-end of the human glycine tRNA synthetase gene

1998 • 49 citations

Analysis of Capsid Formation of Human Polyomavirus JC (Tokyo-1 Strain) by a Eukaryotic Expression System: Splicing of Late RNAs, Translation and Nuclear Transport of Major Capsid Protein VP1, and Capsid Assembly

2000 • 48 citations

Sequences 5′ of the first upstream open reading frame inGCN4mRNA are required for efficient translational reinitiation

1995 • 47 citations

Posttranscriptional mRNA processing as a mechanism for regulation of human A1 adenosine receptor expression.

1994 • 45 citations

Translational regulation of hepatitis B virus polymerase gene by termination-reinitiation of an upstream minicistron in a length-dependent manner.

1998 • 42 citations

Translation inhibition by an mRNA coding region secondary structure is determined by its proximity to the AUG initiation codon

1992 • 42 citations

Adherence to the first-AUG rule when a second AUG codon follows closely upon the first.

1995 • 39 citations

Systemic movement of an RNA plant virus determined by a point substitution in a 5' leader sequence.

1990 • 39 citations

An extended RNA/RNA duplex structure within the coding region of mRNA does not block translational elongation

1988 • 35 citations

The Position Dependence of Translational Regulation via RNA-RNA and RNA-Protein Interactions in the 5′-Untranslated Region of Eukaryotic mRNA Is a Function of the Thermodynamic Competence of 40 S Ribosomes in Translational Initiation

1997 • 30 citations

Elements in the murine c-mos messenger RNA 5'-untranslated region repress translation of downstream coding sequences.

1996 • 28 citations

Regulation of Translation in Eukaryotic Systems

1992 • 28 citations

The 5' Untranslated Regions of the Rat A2A Adenosine Receptor Gene Function as Negative Translational Regulators

1999 • 25 citations

Involvement of upstream open reading frames in regulation of rat V1bvasopressin receptor expression

2001 • 22 citations

Inefficient Reinitiation Is Responsible for Upstream Open Reading Frame-Mediated Translational Repression of the Maize R Gene

1998 • 18 citations

Differential translational initiation of lbp mRNA is caused by a 5′ upstream open reading frame1

1997 • 16 citations

Biosynthesis of Human Fibroblast Growth Factor-5

1991 • 16 citations

Translational Control of Mammalian Serine Hydroxymethyltransferase Expression

1995 • 13 citations

Thrombopoietin Production Is Inhibited by a Translational Mechanism

1998 • 12 citations

Involvement of upstream open reading frames in regulation of rat V1b vasopressin receptor expression

2002 • 2 citations

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Constraints on reinitiation of translation in mammals (2001) – Nucleic Acids Research | Metascience Observatory Explorer