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Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

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Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

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Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

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1982 • 5,284 citations

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The βγ subunits of GTP-binding proteins activate the muscarinic K+ channel in heart

1987 • 1,186 citations

Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs

1992 • 1,067 citations

A G Protein Couples Serotonin and GABA _B Receptors to the Same Channels in Hippocampus

1986 • 870 citations

GTP-binding proteins couple cardiac muscarinic receptors to a K channel

1985 • 868 citations

The G-protein-gated atrial K+ channel IKAch is a heteromultimer of two inwardly rectifying K+-channel proteins

1995 • 830 citations

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1982 • 808 citations

Mu and delta receptors belong to a family of receptors that are coupled to potassium channels.

1987 • 616 citations

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1993 • 600 citations

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1982 • 600 citations

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1987 • 550 citations

Patch clamp measurements onXenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels

1986 • 534 citations

Uncoupling of cardiac muscarinic and β-adrenergic receptors from ion channels by a guanine nucleotide analogue

1985 • 527 citations

Activation of the cloned muscarinic potassium channel by G protein βγ subunits

1994 • 472 citations

Recombinant G-protein βγ-subunits activate the muscarinic-gated atrial potassium channel

1994 • 450 citations

Mode of regulation of the ACh-sensitive K-channel by the muscarinic receptor in rabbit atrial cells

1984 • 436 citations

The inward rectifier potassium channel family

1995 • 426 citations

Cloning and Functional Characterization of a Novel ATP-sensitive Potassium Channel Ubiquitously Expressed in Rat Tissues, including Pancreatic Islets, Pituitary, Skeletal Muscle, and Heart

1995 • 405 citations

[16] Electrophysiologic recordings from Xenopus oocytes

1998 • 361 citations

Atrial G protein-activated K+ channel: expression cloning and molecular properties.

1993 • 355 citations

The α Subunit of the GTP Binding Protein G _k Opens Atrial Potassium Channels

1987 • 317 citations

Evidence that neuronal G-protein-gated inwardly rectifying K+ channels are activated by G beta gamma subunits and function as heteromultimers.

1995 • 304 citations

Electrostatic tuning of Mg2+ affinity in an inward-rectifier K+channel

1994 • 304 citations

Control of rectification and permeation by residues in two distinct domains in an inward rectifier K+ channel

1995 • 304 citations

Cloning provides evidence for a family of inward rectifier and G‐protein coupled K⁺ channels in the brain

1994 • 280 citations

Molecular Properties of Neuronal G-protein-activated Inwardly Rectifying K+ Channels

1995 • 261 citations

Gating of inwardly rectifying K+ channels localized to a single negatively charged residue

1994 • 253 citations

Voltage- and ligand-activated inwardly rectifying currents in dorsal raphe neurons in vitro

1988 • 248 citations

On the mechanism of G protein beta gamma subunit activation of the muscarinic K+ channel in guinea pig atrial cell membrane. Comparison with the ATP-sensitive K+ channel.

1992 • 195 citations

A single aspartate residue is involved in both intrinsic gating and blockage by Mg2+ of the inward rectifier, IRK1.

1994 • 195 citations

Cloning and functional expression of a rat heart KATP channel

1994 • 184 citations

Galanin activates nucleotide-dependent K+ channels in insulin-secreting cells via a pertussis toxin-sensitive G-protein.

1989 • 168 citations

Somatostatin induces an inward rectification in rat locus coeruleus neurones through a pertussis toxin‐sensitive mechanism.

1988 • 157 citations

Heterologous Multimeric Assembly Is Essential for K+ Channel Activity of Neuronal and Cardiac G-Protein-Activated Inward Rectifiers

1995 • 153 citations

Incremental reductions of positive charge within the S4 region of a voltage-gated K+ channel result in corresponding decreases in gating charge

1992 • 142 citations

Specificity of action of guanine nucleotide-binding regulatory protein subunits on the cardiac muscarinic K+ channel.

1988 • 141 citations

Activation by adrenaline of a low-conductance G protein-dependent K+ channel in mouse pancreatic B cells

1991 • 133 citations

An inward‐rectifying K+ current in clonal rat pituitary cells and its modulation by thyrotrophin‐releasing hormone.

1990 • 110 citations

Nomenclature for mammalian potassium channel genes

1993 • 106 citations

A G protein-gated K channel is activated via beta 2-adrenergic receptors and G beta gamma subunits in Xenopus oocytes.

1995 • 102 citations

Expression of an atrial G-protein-activated potassium channel in Xenopus oocytes.

1993 • 85 citations

On the mechanism of basal and agonist-induced activation of the G protein-gated muscarinic K+ channel in atrial myocytes of guinea pig heart.

1991 • 74 citations

A region of the muscarinic-gated atrial K+ channel critical for activation by G protein βγ subunits

1994 • 70 citations

Coupling of the expressed alpha 1B-adrenergic receptor to the phospholipase C pathway in Xenopus oocytes. The role of Go.

1993 • 55 citations

Gating charge differences between two voltagegated K+ channels are due to the specific charge content of their respective S4 regions

1993 • 52 citations

Somatostatin activates glibenclamide‐sensitive and ATP‐regulated K⁺ channels in insulinoma cells via a G‐protein

1988 • 50 citations

The nature and origin of spontaneous noise in G protein-gated ion channels.

1991 • 43 citations

Unitary properties of potassium channels activated by 5‐HT in acutely isolated rat dorsal raphe neurones.

1993 • 43 citations

Guanine nucleotide binding proteins mediate D2 dopamine receptor activation of a potassium channel in rat lactotrophs.

1993 • 39 citations

Activation of G protein-coupled K+ channels by dopamine in human GH-producing cells

1994 • 18 citations

Guanine nucleotide binding proteins mediate D2 dopamine receptor activation of a potassium channel in rat lactotrophs.

1993 • 2 citations