Human T-Lymphotropic Virus Type 1 p30 ^II Regulates Gene Transcription by Binding CREB Binding Protein/p300

A novel genetic system to detect protein–protein interactions

1989 • 6,022 citations

Histone acetylation in chromatin structure and transcription

1997 • 2,834 citations

A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors

1996 • 2,183 citations

Phosphorylated CREB binds specifically to the nuclear protein CBP

1993 • 2,039 citations

Suppression of Human Colorectal Carcinoma Cell Growth by Wild-Type p53

1990 • 1,796 citations

The CBP co-activator is a histone acetyltransferase

1996 • 1,773 citations

CBP/p300 in cell growth, transformation, and development

2000 • 1,712 citations

Nuclear protein CBP is a coactivator for the transcription factor CREB

1994 • 1,447 citations

Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP

1995 • 1,197 citations

Cellular targets for transformation by the adenovirus E1A proteins

1989 • 747 citations

Recruitment of p300/CBP in p53-Dependent Signal Pathways

1997 • 671 citations

Acetylation of general transcription factors by histone acetyltransferases

1997 • 588 citations

Adenoviral ElA-associated protein p300 as a functional homologue of the transcriptional co-activator CBP

1995 • 578 citations

A family of transcriptional adaptor proteins targeted by the E1A oncoprotein

1995 • 534 citations

Conjunction dysfunction: CBP/p300 in human disease

1998 • 406 citations

Control of cAMP-regulated enhancers by the viral transactivator Tax through CREB and the co-activator CBP

1996 • 344 citations

CBP-induced stimulation of c-Fos activity is abrogated by E1A.

1995 • 342 citations

CREB-binding protein and p300: molecular integrators of hematopoietic transcription

2000 • 254 citations

Transcriptional control: Versatile molecular glue

1996 • 231 citations

Retroviral Virions and Genomes

1997 • 224 citations

Complex splicing in the human T-cell leukemia virus (HTLV) family of retroviruses: novel mRNAs and proteins produced by HTLV type I

1992 • 217 citations

Protein isoforms encoded by the pX region of human T-cell leukemia/lymphotropic virus type I.

1992 • 192 citations

Anchoring of CREB Binding Protein to the Human T-Cell Leukemia Virus Type 1 Promoter: a Molecular Mechanism of Tax Transactivation

1997 • 179 citations

An Exposed KID-Like Domain in Human T-Cell Lymphotropic Virus Type 1 Tax Is Responsible for the Recruitment of Coactivators CBP/p300

1998 • 174 citations

Acetylation of HIV-1 Tat by CBP/P300 Increases Transcription of Integrated HIV-1 Genome and Enhances Binding to Core Histones

2000 • 155 citations

The SV40 large T antigen and adenovirus E1a oncoproteins interact with distinct isoforms of the transcriptional co-activator, p300.

1996 • 147 citations

Inhibition of p300 Histone Acetyltransferase by Viral Interferon Regulatory Factor

2000 • 135 citations

The p12I, p13II, and p30II proteins encoded by human T-cell leukemia/lymphotropic virus type I open reading frames I and II are localized in three different cellular compartments

1993 • 131 citations

Functional Role of pX Open Reading Frame II of Human T-Lymphotropic Virus Type 1 in Maintenance of Viral Loads In Vivo

2000 • 127 citations

Transactivation and growth suppression by the gut-enriched Kruppel-like factor (Kruppel-like factor 4) are dependent on acidic amino acid residues and protein-protein interaction

2000 • 125 citations

Construction and Characterization of Infectious Human T-Cell Leukemia Virus Type 1 Molecular Clones

1994 • 120 citations

Regulation of Gene Expression by HTLV-I Tax Protein

1998 • 120 citations

HTLV-1 Tax oncoprotein represses the p53-mediated trans-activation function through coactivator CBP sequestration

2000 • 118 citations

Multiple Control Levels of Cell Proliferation by Human T-Cell Leukemia Virus Type 1 Tax Protein

1999 • 100 citations

Mitochondrial targeting of the p13II protein coded by the x-II ORF of human T-cell leukemia/lymphotropic virus type I (HTLV-I)

1999 • 95 citations

Tax protein of HTLV-1 inhibits CBP/p300-mediated transcription by interfering with recruitment of CBP/p300 onto DNA element of E-box or p53 binding site

1999 • 94 citations

Human T-Lymphotropic Virus Type 1 p30 ^II Functions as a Transcription Factor and Differentially Modulates CREB-Responsive Promoters

2000 • 80 citations

The upstream stimulatory factor binds to and activates the promoter of the rat class I alcohol dehydrogenase gene

1991 • 69 citations

Erythroid Krüppel-like factor (EKLF) contains a multifunctional transcriptional activation domain important for inter- and intramolecular interactions.

1996 • 68 citations

The Coactivator CBP Stimulates Human T-cell Lymphotrophic Virus Type I Tax Transactivation in Vitro

1998 • 67 citations

The Human T-Cell Leukemia Virus Type 1 Oncoprotein Tax Inhibits the Transcriptional Activity of c-Myb through Competition for the CREB Binding Protein

1998 • 58 citations

Human T-cell lymphotropic virus type 1 Tax mediates enhanced transcription in CD4+ T lymphocytes

1996 • 53 citations

Molecular interactions between the coactivator CBP and the human T-cell leukemia virus tax protein

1998 • 52 citations

Binding of the human T-cell leukemia virus Tax protein to the coactivator CBP interferes with CBP-mediated transcriptional control

1999 • 49 citations

Eukaryotic GST fusion vector for the study of protein-protein associations in vivo: application to interaction of ATFa with Jun and Fos.

1995 • 48 citations

Differential expression of alternatively spliced pX mRNAs in HTLV-I-infected cell lines

1997 • 46 citations

Insights into the Molecular Mechanism of p53 Inhibition by HTLV Type 1 Tax

2000 • 46 citations

The tax protein-DNA interaction is essential for HTLV-I transactivation in Vitro

1999 • 46 citations

Human T-Cell Leukemia Virus Type 2 Rex Protein Increases Stability and Promotes Nuclear to Cytoplasmic Transport of gag/pol and env RNAs

1999 • 41 citations

The HTLV-I orfI Protein Is Recognized by Serum Antibodies from Naturally Infected Humans and Experimentally Infected Rabbits

2000 • 36 citations

HTLV-I Tax and cell cycle progression

2000 • 33 citations

General effect of Sam68 on Rev/Rex regulated expression of complex retroviruses

2000 • 32 citations

Influence of Rex and Intronic Sequences on Expression of Spliced mRNAs Produced by Human T Cell Leukemia Virus Type I

1999 • 10 citations

In VivoProduction of Rof and Tof Proteins of HTLV Type 1: Evidence from Cytotoxic T Lymphocytes

2000 • 10 citations

Comparison of HTLV-I Basal Transcription and Expression of CREB/ATF-1/CREM Family Members in Peripheral Blood Mononuclear Cells and Jurkat T Cells

1999 • 7 citations