Maf nuclear oncoprotein recognizes sequences related to an AP-1 site and forms heterodimers with both Fos and Jun

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

Human Proto-Oncogene c- jun Encodes a DNA Binding Protein with Structural and Functional Properties of Transcription Factor AP-1

1987 • 1,353 citations

Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity.

1991 • 1,300 citations

c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities

1988 • 1,084 citations

Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers.

1989 • 1,046 citations

Scissors-Grip Model for DNA Recognition by a Family of Leucine Zipper Proteins

1989 • 996 citations

Nucleotide sequence of the hepatitis B virus genome (subtype ayw) cloned in E. coli

1979 • 992 citations

A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence

1989 • 914 citations

Nucleotide sequence of rous sarcoma virus

1983 • 901 citations

DNA binding activities of three murine Jun proteins: Stimulation by Fos

1988 • 850 citations

The role of the leucine zipper in the fos–jun interaction

1988 • 836 citations

Cyclic AMP-Responsive DNA-Binding Protein: Structure Based on a Cloned Placental cDNA

1988 • 772 citations

A gene activated by growth factors is related to the oncogene v-jun.

1988 • 771 citations

CREM gene: Use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription

1991 • 655 citations

Erythroid transcription factor NF-E2 is a haematopoietic-specific basic–leucine zipper protein

1993 • 655 citations

Fos-Associated Protein p39 Is the Product of the jun Proto-Oncogene

1988 • 643 citations

The product of a novel growth factor activated gene, fos B, interacts with JUN proteins enhancing their DNA binding activity.

1989 • 572 citations

Sequence of the human insulin gene

1980 • 553 citations

fra-1: a serum-inducible, cellular immediate-early gene that encodes a fos-related antigen.

1988 • 518 citations

Isolation and nucleotide sequence of the gene encoding human rhodopsin.

1984 • 495 citations

Characterization of junD: a new member of the jun proto-oncogene family.

1989 • 492 citations

jun-D: a third member of the jun gene family.

1989 • 469 citations

Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain

1988 • 455 citations

Avian sarcoma virus 17 carries the jun oncogene.

1987 • 445 citations

Isolation and sequence analysis of the human corticotropin-releasing factor precursor gene.

1983 • 420 citations

Leucine zipper structure of the protein CRE-BP1 binding to the cyclic AMP response element in brain.

1989 • 396 citations

Regulation of human NAD(P)H:quinone oxidoreductase gene. Role of AP1 binding site contained within human antioxidant response element.

1992 • 353 citations

Complete structure of the human gene for 92-kDa type IV collagenase. Divergent regulation of expression for the 92- and 72-kilodalton enzyme genes in HT-1080 cells.

1991 • 343 citations

jun:Oncogene and Transcription Factor

1990 • 337 citations

Two tissue-specific factors bind the erythroid promoter of the human porphobilinogen deaminase gene

1989 • 326 citations

Alternative transcription and splicing of the human porphobilinogen deaminase gene result either in tissue-specific or in housekeeping expression.

1988 • 313 citations

A conserved retina-specific gene encodes a basic motif/leucine zipper domain.

1992 • 308 citations

Isolation and characterization of fra-2, an additional member of the fos gene family.

1990 • 274 citations

Different requirements for formation of Jun: Jun and Jun: Fos complexes.

1989 • 272 citations

Cis- and trans-acting elements involved in the regulation of the erythroid promoter of the human porphobilinogen deaminase gene.

1989 • 272 citations

v-maf, a viral oncogene that encodes a "leucine zipper" motif.

1989 • 266 citations

Complete nucleotide sequence of a milk-transmitted mouse mammary tumor virus: two frameshift suppression events are required for translation of gag and pol

1987 • 258 citations

Two adjacent AP-1-like binding sites form the electrophile-responsive element of the murine glutathione S-transferase Ya subunit gene.

1992 • 230 citations

Activation of the human "beta 2-interferon/hepatocyte-stimulating factor/interleukin 6" promoter by cytokines, viruses, and second messenger agonists.

1988 • 215 citations

Human NAD(P)H:quinone oxidoreductase (NQO1) gene structure and induction by dioxin

1991 • 213 citations

The primary structure of the putative oncogene pim-1 shows extensive homology with protein kinases

1986 • 198 citations

Asymmetrical recognition of the palindromic AP1 binding site (TRE) by Fos protein complexes.

1989 • 191 citations

Strong sequence conservation among horizontally transmissible, minimally pathogenic feline leukemia viruses

1988 • 174 citations

Structure-function analysis of the maf oncogene product, a member of the b-Zip protein family

1993 • 161 citations

Multiple regulatory elements and phorbol 12-O-tetradecanoate 13-acetate responsiveness of the rat placental glutathione transferase gene.

1988 • 154 citations

The 5′ region of the p53 gene: evolutionary conservation and evidence for a negative regulatory element.

1985 • 146 citations

Identification of LRF-1, a leucine-zipper protein that is rapidly and highly induced in regenerating liver.

1991 • 139 citations

The basic region of Fos mediates specific DNA binding.

1989 • 132 citations

The structure of the rat glutathione S-transferase P gene and related pseudogenes.

1987 • 131 citations

Multiple nuclear proteins in liver cells are bound to hepatitis B virus enhancer element and its upstream sequences.

1987 • 119 citations

Conservation of the primary structure, organization, and function of the human and mouse beta-globin locus-activating regions.

1990 • 112 citations

Isolation and characterization of two novel, closely related ATF cDNA clones from HeLa cells

1990 • 103 citations

Protooncogene c-fos as a Transcription Factor

1990 • 93 citations

Cell-cycle regulatory sequences in a hamster histone promoter and their interactions with cellular factors

1987 • 89 citations

Isolation and characterization of a novel member of the gene family encoding the cAMP response element-binding protein CRE-BP1.

1993 • 80 citations

Cooperative Function of Two Separate Enhancers of the Human Epidermal Growth Factor Receptor Proto-oncogene

1989 • 79 citations

Multiple members of the plasminogen-apolipoprotein(a) gene family associated with thrombosis

1992 • 78 citations

Multiple regulatory elements of the murine γ2-crystallin promoter

1989 • 66 citations

Structure and expression of the human metallothionein-IG gene. Differential promoter activity of two linked metallothionein-I genes in response to heavy metals.

1988 • 58 citations

Structure and expression of a cluster of human hematopoietic serine protease genes found on chromosome 14q11.2.

1991 • 57 citations

A single element within the hepatitis B virus enhancer binds multiple proteins and responds to multiple stimuli

1990 • 55 citations

An avian transforming retrovirus isolated from a nephroblastoma that carries the fos gene as the oncogene

1987 • 48 citations

Isolation of the avian transforming retrovirus, AS42, carrying the v-maf oncogene and initial characterization of its gene product

1992 • 45 citations

Interaction of cellular factors related to the Jun oncoprotein with the promoter of a replication-dependent hamster histone H3.2 gene.

1989 • 42 citations