Adiponectin suppresses colorectal carcinogenesis under the high-fat diet condition

Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults

2003 • 7,305 citations

TOR Signaling in Growth and Metabolism

2006 • 5,643 citations

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

2001 • 4,874 citations

Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity

1999 • 4,825 citations

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

2002 • 4,335 citations

Plasma Concentrations of a Novel, Adipose-Specific Protein, Adiponectin, in Type 2 Diabetic Patients

2000 • 3,142 citations

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

2003 • 3,114 citations

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

2001 • 2,534 citations

Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions

2007 • 1,305 citations

ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism

2002 • 1,210 citations

Physical Activity, Obesity, and Risk for Colon Cancer and Adenoma in Men

1995 • 1,014 citations

Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl–CoA carboxylase inhibition and AMP-activated protein kinase activation

2002 • 969 citations

Insulin, Insulin-Like Growth Factors and Colon Cancer: A Review of the Evidence

2001 • 941 citations

Overweight, obesity, and cancer risk

2002 • 899 citations

Enhanced expression of PAI–1 in visceral fat: Possible contributor to vascular disease in obeisty

1996 • 886 citations

Obesity in the new millennium

2000 • 707 citations

Mice Lacking Adiponectin Show Decreased Hepatic Insulin Sensitivity and Reduced Responsiveness to Peroxisome Proliferator-activated Receptor γ Agonists

2005 • 621 citations

An expanding role for mTOR in cancer

2005 • 519 citations

Increased Blood Glucose and Insulin, Body Size, and Incident Colorectal Cancer

1999 • 496 citations

Low Plasma Adiponectin Levels and Risk of Colorectal Cancer in Men: A Prospective Study

2005 • 492 citations

Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults*

2003 • 437 citations

AMPK, the metabolic syndrome and cancer

2005 • 415 citations

Upstream of the mammalian target of rapamycin: do all roads pass through mTOR?

2006 • 388 citations

mTOR and P70 S6 Kinase Expression in Primary Liver Neoplasms

2004 • 372 citations

Secretion of Adiponectin and Regulation of apM1 Gene Expression in Human Visceral Adipose Tissue

2001 • 351 citations

Aberrant crypts: potential preneoplastic lesions in the murine colon.

1988 • 305 citations

Adiponectin Modulates the Glycogen Synthase Kinase-3β/β-Catenin Signaling Pathway and Attenuates Mammary Tumorigenesis of MDA-MB-231 Cells in Nude Mice

2006 • 269 citations

When translation meets transformation: the mTOR story

2006 • 199 citations

Peroxisome proliferator-activated receptor γ ligands suppress colon carcinogenesis induced by azoxymethane in mice

2003 • 193 citations

Dietary fat and colon cancer: Animal model studies

1992 • 185 citations

The p70 S6 Kinase Integrates Nutrient and Growth Signals to Control Translational Capacity

2001 • 180 citations

The role of fat, fatty acids, and total energy intake in the etiology of human colon cancer

1997 • 156 citations

Regulation of adiponectin and its receptors in response to development of diet-induced obesity in mice

2006 • 145 citations

The tumor suppressor p53: Cancer and aging

2008 • 110 citations

Serum Adiponectin is not Associated with Risk of Colorectal Cancer

2006 • 103 citations

Modeling human colon cancer in rodents using a food‐borne carcinogen, PhIP

2005 • 69 citations

Leptin and adiponectin interact in the regulation of prostate cancer cell growth via modulation of p53 and bcl‐2 expression

2008 • 59 citations

Human aberrant crypt foci with carcinoma in situ from a patient with sporadic colon cancer

1996 • 58 citations

Leptin treatment markedly increased plasma adiponectin but barely decreased plasma resistin of ob/ob mice

2004 • 55 citations

Dietary fats and cancer

2001 • 39 citations