Back to search

The Chromosomal Passenger Complex Is Required for Chromatin-Induced Microtubule Stabilization and Spindle Assembly

Data up to Jan 2025

Published2004
Citations412
References51

Total Citations Per Year

Abstract

References (51)

Cyclin is degraded by the ubiquitin pathway

1991 • 2,355 citations

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

2003 • 1,175 citations

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore–microtubule attachment and in maintaining the spindle assembly checkpoint

2003 • 1,144 citations

The cellular geography of Aurora kinases

2003 • 1,118 citations

Principles of Development

2019 • 1,040 citations

Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate.

1994 • 1,032 citations

Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts

1996 • 978 citations

Chapter 30 Cell Cycle Extracts

1991 • 953 citations

Evidence that the Ipl1-Sli15 (Aurora Kinase-INCENP) Complex Promotes Chromosome Bi-orientation by Altering Kinetochore-Spindle Pole Connections

2002 • 725 citations

Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

1991 • 703 citations

Kin I Kinesins Are Microtubule-Destabilizing Enzymes

1999 • 697 citations

Ran Induces Spindle Assembly by Reversing the Inhibitory Effect of Importin α on TPX2 Activity

2001 • 592 citations

XKCM1: A Xenopus Kinesin-Related Protein That Regulates Microtubule Dynamics during Mitotic Spindle Assembly

1996 • 539 citations

Chromosomal passengers and the (aurora) ABCs of mitosis

2001 • 535 citations

Aurora B Regulates MCAK at the Mitotic Centromere

2004 • 527 citations

Visualization of a Ran-GTP Gradient in Interphase and Mitotic Xenopus Egg Extracts

2002 • 526 citations

Centrosome-independent mitotic spindle formation in vertebrates

2000 • 502 citations

Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation

1999 • 492 citations

Correcting improper chromosome–spindle attachments during cell division

2004 • 448 citations

The Mitotic Spindle: A Self-Made Machine

2001 • 447 citations

Aurora B Phosphorylates Centromeric MCAK and Regulates Its Localization and Microtubule Depolymerization Activity

2004 • 443 citations

The inner centromere protein (INCENP) antigens: movement from inner centromere to midbody during mitosis.

1987 • 407 citations

Stimulation of Microtubule Aster Formation and Spindle Assembly by the Small GTPase Ran

1999 • 393 citations

Importin β Is a Mitotic Target of the Small GTPase Ran in Spindle Assembly

2001 • 374 citations

The Ran GTPase regulates mitotic spindle assembly

1999 • 349 citations

A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly

2003 • 341 citations

Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis

2002 • 333 citations

Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts

1999 • 327 citations

Role of Importin-β in Coupling Ran to Downstream Targets in Microtubule Assembly

2001 • 318 citations

Aurora B Kinase Exists in a Complex with Survivin and INCENP and Its Kinase Activity Is Stimulated by Survivin Binding and Phosphorylation

2002 • 318 citations

The Xenopus Chromokinesin Xkid Is Essential for Metaphase Chromosome Alignment and Must Be Degraded to Allow Anaphase Chromosome Movement

2000 • 310 citations

INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow

2000 • 307 citations

Self-Organization of Microtubule Asters Induced in Xenopus Egg Extracts by GTP-Bound Ran

1999 • 305 citations

Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes

2000 • 283 citations

Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4

1993 • 261 citations

Ran–GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly

2001 • 243 citations

The centrosome in vertebrates: more than a microtubule-organizing center

2001 • 232 citations

Differentiation of Cytoplasmic and Meiotic Spindle Assembly MCAK Functions by Aurora B-dependent Phosphorylation

2004 • 220 citations

Reconstitution of Physiological Microtubule Dynamics Using Purified Components

2001 • 210 citations

Analysis of the distribution of the INCENPs throughout mitosis reveals the existence of a pathway of structural changes in the chromosomes during metaphase and early events in cleavage furrow formation

1991 • 176 citations

Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells

2004 • 128 citations

Part of Ran Is Associated with AKAP450 at the Centrosome: Involvement in Microtubule-organizing Activity

2003 • 127 citations

An Inner Centromere Protein that Stimulates the Microtubule Depolymerizing Activity of a KinI Kinesin

2003 • 115 citations

Captivating Capture: How Microtubules Attach to Kinetochores

2003 • 108 citations

CSC-1

2003 • 96 citations

Beyond Nuclear Transport

1999 • 91 citations

Regulation of Op18 during Spindle Assembly in Xenopus Egg Extracts

2001 • 86 citations

Drug Target Discovery by Gene Expression Analysis Cell Cycle Genes

2001 • 80 citations

The Mitotic Spindle

1989 • 48 citations

[41] Purification of cytoskeletal proteins using peptide antibodies

1998 • 32 citations

Separating centrosomes interact in the absence of associated chromosomes during mitosis in cultured vertebrate cells

2002 • 28 citations

Cited By (0)

Loading...
The Chromosomal Passenger Complex Is Required for Chromatin-Induced Microtubule… (2004) – Cell | Metascience Observatory Explorer