Thirty Years of Investigating the Autoimmune Basis for Type 1 Diabetes

Immunologic tolerance maintained by CD25⁺ CD4⁺ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

2001 • 1,515 citations

Type 1 diabetes: new perspectives on disease pathogenesis and treatment

2001 • 1,477 citations

ISLET-CELL ANTIBODIES IN DIABETES MELLITUS WITH AUTOIMMUNE POLYENDOCRINE DEFICIENCIES

1974 • 1,463 citations

Pathologic Anatomy of the Pancreas in Juvenile Diabetes Mellitus

1965 • 1,338 citations

Anti-CD3 Monoclonal Antibody in New-Onset Type 1 Diabetes Mellitus

2002 • 1,189 citations

HL-A ANTIGENS AND DIABETES MELLITUS

1974 • 802 citations

Termination of Pregnancy on Psychiatric Grounds

1964 • 683 citations

Multiple immuno-regulatory defects in type-1 diabetes

2002 • 645 citations

The NOD mouse model of type 1 diabetes: As good as it gets?

1999 • 592 citations

Early Infant Feeding and Risk of Developing Type 1 Diabetes–Associated Autoantibodies

2003 • 567 citations

Multiple immuno-regulatory defects in type-1 diabetes

2002 • 548 citations

Timing of Initial Cereal Exposure in Infancy and Risk of Islet Autoimmunity

2003 • 519 citations

Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

2004 • 482 citations

Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes.

1994 • 452 citations

Clinical islet transplantation: advances and immunological challenges

2004 • 360 citations

RELATION BETWEEN BREAST-FEEDING AND INCIDENCE RATES OF INSULIN-DEPENDENT DIABETES MELLITUS

1984 • 344 citations

ANTIBODIES TO PANCREATIC ISLET CELLS IN INSULIN-DEPENDENT DIABETICS WITH COEXISTENT AUTOIMMUNE DISEASE

1974 • 329 citations

The role of viruses in human diabetes

2002 • 309 citations

The Genetics of Diabetes Mellitus

1970 • 276 citations

Response of peripheral-blood mononuclear cells to glutamate decarboxylase in insulin-dependent diabetes

1992 • 275 citations

Stratification of Type 1 Diabetes Risk on the Basis of Islet Autoantibody Characteristics

2004 • 271 citations

A missing link in the hygiene hypothesis?

2002 • 246 citations

Satisfaction (not) guaranteed: re-evaluating the use of animal models of type 1 diabetes

2004 • 209 citations

Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus

2004 • 183 citations

Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus

2004 • 173 citations

Lack of Immune Responsiveness to Bovine Serum Albumin in Insulin-Dependent Diabetes

1993 • 163 citations

Insulin Secretion in Type 1 Diabetes

2004 • 162 citations

Relationship Between Cows' Milk Consumption and Incidence of IDDM in Childhood

1991 • 144 citations

Screening Strategies for the Identification of Multiple Antibody-Positive Relatives of Individuals with Type 1 Diabetes

2003 • 122 citations

Prevention of diabetes in the NOD mouse: implications for therapeutic intervention in human disease

1994 • 108 citations

Milk Proteins in the Etiology of Insulin-Dependent Diabetes Mellitus (IDDM)

1991 • 103 citations

Induction, acceleration or prevention of autoimmunity by molecular mimicry

2003 • 99 citations

Animal models have little to teach us about Type 1 diabetes: 1. In support of this proposal

2004 • 87 citations

Relationship of beta-cell function and autoantibodies to progression and nonprogression of subclinical type 1 diabetes: follow-up of the Seattle Family Study.

1999 • 86 citations

Progenitor cells in the adult pancreas

2004 • 73 citations

Insulin for the world's poorest countries

2000 • 67 citations

Genetics of type 1 diabetes

2004 • 66 citations

Diabetes in the young: a paediatric and epidemiological perspective

2003 • 62 citations

The Role of B Lymphocytes as Key Antigen-Presenting Cells in the Development of T Cell-Mediated Autoimmune Type 1 Diabetes

2002 • 55 citations

Costs of predicting IDDM

1998 • 53 citations

Group size, cage shelf level, and emotionality in non-obese diabetic mice: impact on onset and incidence of IDDM.

1991 • 51 citations

Animal models have little to teach us about Type 1 diabetes: 2. In opposition to this proposal

2004 • 50 citations

Immune cells, pancreas development, regeneration and type 1 diabetes

2004 • 46 citations

Differential Recognition and Activation Thresholds in Human Autoreactive GAD-Specific T-Cells

2004 • 46 citations

Insulin Autoimmunity

2003 • 39 citations

Genetic susceptibility in type 1 diabetes and its associated autoimmune disorders.

2003 • 32 citations

Overview of prevention and intervention trials for type 1 diabetes.

2003 • 31 citations

On the Mechanisms of the Protective Effect of Infections on Type 1 Diabetes

2004 • 31 citations

Toward Precise Forecasting of Autoimmune Endocrinopathy

2004 • 30 citations

Prevention Strategies for Type 1 Diabetes Mellitus

2003 • 29 citations

AUTOIMMUNITY IN DIABETES MELLITUS

1970 • 27 citations

Autoreactive T cells in endocrine/organ-specific autoimmunity: why has progress been so slow?

2002 • 22 citations

Treatment of type 1 diabetes mellitus to preserve insulin secretion

2004 • 13 citations

Type 1 Diabetes as a Model for Prediction and Diagnosis

2004 • 12 citations

Commentary: Modification of the Environment Is Not the Most Efficient Way to Prevent Type 1 Diabetes

2000 • 8 citations

Deleted Work

1955 • 0 citations

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