Multiple Mechanisms of Action for Inhibitors of Histidine Protein Kinases from Bacterial Two-Component Systems

Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically

2000 • 16,578 citations

Two-Component Signal Transduction

2000 • 3,517 citations

Protein phosphorylation and regulation of adaptive responses in bacteria

1989 • 1,495 citations

COMMUNICATION MODULES IN BACTERIAL SIGNALING PROTEINS

1992 • 1,449 citations

Two-Component Signal Transduction

1995 • 752 citations

Peptide Helicity and Membrane Surface Charge Modulate the Balance of Electrostatic and Hydrophobic Interactions with Lipid Bilayers and Biological Membranes

1996 • 393 citations

Compilation of All Genes Encoding Two-component Phosphotransfer Signal Transducers in the Genome of Escherichia coli

1997 • 384 citations

Negative control of bacterial DNA replication by a cell cycle regulatory protein that binds at the chromosome origin

1998 • 333 citations

The VanS-VanR two-component regulatory system controls synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147

1992 • 327 citations

Structural conservation in the CheY superfamily

1993 • 288 citations

Regulation of polymyxin resistance and adaptation to low-Mg2+ environments

1997 • 281 citations

The Two-Component System1

1998 • 263 citations

Characterization of the gene for a protein kinase which phosphorylates the sporulation-regulatory proteins Spo0A and Spo0F of Bacillus subtilis

1989 • 235 citations

Protein histidine kinases and signal tranduction in prokaryotes and eukaryotes

1994 • 233 citations

Structure of the magnesium-bound form of CheY and mechanism of phosphoryl transfer in bacterial chemotaxis

1993 • 215 citations

Daptomycin disrupts membrane potential in growing Staphylococcus aureus

1991 • 211 citations

A two‐component signal‐transducing system is involved in competence and penicillin susceptibility in laboratory mutants of Streptococcus pneumoniae

1994 • 204 citations

Histidine kinases in signal transduction pathways of eukaryotes

1997 • 173 citations

Multiple Mechanisms of Action for Inhibitors of Histidine Protein Kinases from Bacterial Two-Component Systems

1999 • 169 citations

Signal transduction via the histidyl‐aspartyl phosphorelay

1997 • 165 citations

Insights into Multistep Phosphorelay from the Crystal Structure of the C-Terminal HPt Domain of ArcB

1997 • 159 citations

Mechanism of autophosphorylation of Escherichia coli nitrogen regulator II (NRII or NtrB): trans-phosphorylation between subunits

1993 • 158 citations

Flow cytometric assessment of Escherichia coli and Salmonella typhimurium starvation-survival in seawater using rhodamine 123, propidium iodide, and oxonol

1995 • 152 citations

Lipoteichoic acid as a new target for activity of antibiotics: mode of action of daptomycin (LY146032)

1990 • 149 citations

Compilation of All Genes Encoding Bacterial Two-component Signal Transducers in the Genome of the Cyanobacterium, Synechocystis sp. Strain PCC 6803

1996 • 144 citations

Structure of the CheY-binding domain of histidine kinase CheA in complex with CheY

1998 • 129 citations

Substituted Salicylanilides as Inhibitors of Two-Component Regulatory Systems in Bacteria

1998 • 128 citations

Mechanism of membrane damage induced by the amphipathic peptides gramicidin S and melittin

1989 • 126 citations

Antibacterial agents that inhibit two-component signal transduction systems

1998 • 123 citations

Inhibitors of two-component signal transduction systems: inhibition of alginate gene activation in Pseudomonas aeruginosa.

1993 • 106 citations

Molecular recognition in signal transduction: the interaction surfaces of the Spo0F response regulator with its cognate phosphorelay proteins revealed by alanine scanning mutagenesis

1997 • 104 citations

The Mechanism of the Bacteriostatic Action of Tetrachlorosalicylanilide: a Membrane-active Antibacterial Compound

1968 • 95 citations

Mechanism of action of uncouplers of oxidative phosphorylation

1971 • 90 citations

Genes involved in production of plasmidlike forms by a Bacteroides conjugal chromosomal element share amino acid homology with two-component regulatory systems

1992 • 79 citations

Expression of the AsbA1, OXA-12, and AsbM1 beta-lactamases in Aeromonas jandaei AER 14 is coordinated by a two-component regulon

1997 • 68 citations

Novel inhibitors of bacterial two-component systems with gram positive antibacterial activity: Pharmacophore identification based on the screening hit closantel

1998 • 67 citations

Crystal structure of a phosphatase-resistant mutant of sporulation response regulator Spo0F from Bacillus subtilis

1996 • 66 citations

A Second Two-Component Regulatory System of Bordetella bronchiseptica Required for Bacterial Resistance to Oxidative Stress, Production of Acid Phosphatase, and In Vivo Persistence

1998 • 62 citations

Identification and characterization of a two-component regulatory system involved in invasion of eukaryotic cells and heavy-metal resistance in Burkholderia pseudomallei

1997 • 61 citations

Two-Component Signal Transduction and Its Role in the Expression of Bacterial Virulence Factors

2014 • 52 citations

Purification and characterization of a hemolysin produced by Vibrio mimicus

1997 • 49 citations

Effect of leukocyte hydrolases on bacteria xvi

1982 • 30 citations

Mechanistic studies and biological activity of bioxalomycin alpha 2, a novel antibiotic produced by Streptomyces viridodiastaticus subsp. "litoralis" LL-31F508

1994 • 24 citations

Effect of leukocyte hydrolases on bacteria

1979 • 22 citations

How anthelmintics help us to understand helminths

1985 • 21 citations

Flukicidal action of closantel against immature and mature Fasciola hepatica in experimentally infected rats and sheep

1988 • 18 citations

Bacterial Two-Component Signalling as a Therapeutic Target in Drug Design

1998 • 12 citations

A comparative study of biological activities of lipoteichoic acid and lipopolysaccharide

1995 • 8 citations