Transcriptional control by Drosophila gap genes

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Mutations affecting segment number and polarity in Drosophila

1980 • 4,280 citations

How eukaryotic transcriptional activators work

1988 • 1,924 citations

The Embryonic Development of Drosophila melanogaster

1985 • 1,371 citations

The origin of pattern and polarity in the Drosophila embryo

1992 • 1,367 citations

The molecular genetics of embryonic pattern formation in Drosophila

1988 • 1,048 citations

The molecular basis for metameric pattern in the Drosophila embryo

1987 • 1,028 citations

The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner

1988 • 1,022 citations

A gradient of bicoid protein in Drosophila embryos

1988 • 1,015 citations

Gene regulation by proteins acting nearby and at a distance

1986 • 886 citations

The role of localization of bicoid RNA in organizing the anterior pattern of the Drosophila embryo.

1988 • 736 citations

The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo

1989 • 672 citations

The gradient morphogen bicoid is a concentration-dependent transcriptional activator

1989 • 655 citations

Determination of Anteroposterior Polarity in Drosophila

1987 • 651 citations

Nanos is the localized posterior determinant in Drosophila

1991 • 510 citations

Structure of the segmentation gene paired and the Drosophila PRD gene set as part of a gene network

1986 • 496 citations

Transcriptional repression of eukaryotic promoters

1989 • 481 citations

Determination of spatial domains of zygotic gene expression in the Drosophila embryo by the affinity of binding sites for the bicoid morphogen

1989 • 432 citations

Structural homology of the product of the Drosophila Krüppel gene with Xenopus transcription factor IIIA

1986 • 406 citations

Control elements of the Drosophila segmentation gene fushi tarazu

1985 • 404 citations

Organization of anterior pattern in the Drosophila embryo by the maternal gene bicoid

1986 • 386 citations

Finger protein of novel structure encoded by hunchback, a second member of the gap class of Drosophila segmentation genes

1987 • 370 citations

Regulation of the Drosophila segmentation gene hunchback by two maternal morphogenetic centres

1988 • 366 citations

The Drosophila gene tailless is expressed at the embryonic termini and is a member of the steroid receptor superfamily

1990 • 361 citations

Transcriptional regulation of a pair-rule stripe in Drosophila.

1991 • 354 citations

The Drosophila gene torso encodes a putative receptor tyrosine kinase

1989 • 327 citations

Regulation of a Segmentation Stripe by Overlapping Activators and Repressors in the Drosophila Embryo

1991 • 321 citations

The Drosophila posterior-group gene nanos functions by repressing hunchback activity

1989 • 301 citations

Control of Drosophila body pattern by the hunchback morphogen gradient

1992 • 294 citations

hunchback, a gene required for segmentation of an anterior and posterior region of the Drosophila embryo

1987 • 289 citations

Early and late periodic patterns of even skipped expression are controlled by distinct regulatory elements that respond to different spatial cues

1989 • 273 citations

Sequence-specific DNA-binding activities of the gap proteins encoded by hunchback and Krüppel in Drosophila

1989 • 270 citations

A morphogenetic gradient of hunchback protein organizes the expression of the gap genes Krüppel and knirps in the early Drosophila embryo

1990 • 258 citations

Autoregulatory and gap gene response elements of the even-skipped promoter of Drosophila.

1989 • 254 citations

Molecular genetics of Krüppel, a gene required for segmentation of the Drosophila embryo

1985 • 235 citations

Function of torso in determining the terminal anlagen of the Drosophila embryo

1988 • 228 citations

Drosophila Krüppel protein is a transcriptional represser

1990 • 228 citations

Analysis of Krüppel protein distribution during early Drosophila development reveals posttranscriptional regulation

1987 • 222 citations

Abdominal segmentation of the Drosophila embryo requires a hormone receptor-like protein encoded by the gap gene knirps

1988 • 217 citations

Two Gap Genes Mediate Maternal Terminal Pattern Information in Drosophila

1990 • 214 citations

Posterior segmentation of the Drosophila embryo in the absence of a maternal posterior organizer gene

1989 • 198 citations

Krüppel, a gene whose activity is required early in the zygotic genome for normal embryonic segmentation

1984 • 189 citations

Spatial and temporal patterns of Krüppel gene expression in early Drosophila embryos

1985 • 175 citations

Cross-regulatory interactions among the gap genes of Drosophila

1986 • 168 citations

Concentration-dependent transcriptional activation or repression by Krüppel from a single binding site

1991 • 166 citations

Localized requirement for torso-like expression in follicle cells for development of terminal anlagen of the Drosophila embryo

1990 • 160 citations

Determination of the embryonic axes of Drosophila.

1991 • 160 citations

Mutually repressive interactions between the gap genes giant and Krüppel define middle body regions of the Drosophila embryo

1991 • 159 citations

Spatial regulation of the gap gene giant during Drosophila development

1991 • 157 citations

Interactions of the Drosophila gap gene giant with maternal and zygotic pattern-forming genes

1991 • 152 citations

Differential regulation of the two transcripts from the Drosophila gap segmentation gene hunchback.

1988 • 149 citations

The products of the Drosophila gap genes hunchback and Krüppel bind to the hunchback promoters

1989 • 146 citations

Competition for Overlapping Sites in the Regulatory Region of the Drosophila Gene Krüppel

1992 • 145 citations

Krüppel requirement for knirps enhancement reflects overlapping gap gene activities in the Drosophila embryo

1989 • 140 citations

Control and function of terminal gap gene activity in the posterior pole region of the Drosophila embryo

1991 • 137 citations

Gradients of Krüppel and knirps gene products direct pair-rule gene stripe patterning in the posterior region of the drosophila embryo

1990 • 137 citations

Three hormone receptor-like Drosophila genes encode an identical DNA-binding finger.

1989 • 127 citations

Pole region-dependent repression of the Drosophila gap gene Krüppel by maternal gene products

1987 • 124 citations

Making stripes in the Drosophila embryo

1990 • 124 citations

cis-acting control elements for Krüppel expression in the Drosophila embryo.

1990 • 120 citations

Individual stripe regulatory elements in the Drosophila hairy promoter respond to maternal, gap, and pair-rule genes.

1991 • 117 citations

The giant gene of Drosophila encodes a b-ZIP DNA-binding protein that regulates the expression of other segmentation gap genes

1992 • 112 citations

Dual Role of the Drosophila Pattern Gene tailless in Embryonic Termini

1991 • 111 citations

Gene expression mediated by cis-acting sequences of the Krüppel gene in response to the Drosophila morphogens bicoid and hunchback.

1991 • 110 citations

Graded requirement for the zygotic terminal gene,tailless, in the brain and tail region of theDrosophilaembryo

1988 • 104 citations

A novel spatial transcription pattern associated with the segmentation gene, giant, of Drosophila.

1989 • 96 citations

Gap genes and gradients – The logic behind the gaps

1991 • 95 citations

Region-specific alleles of the Drosophila segmentation gene hairy.

1988 • 91 citations

Spatial Control of the Gap Gene knirps in the Drosophila Embryo by Posterior Morphogen System

1992 • 84 citations

Analysis of maternal effect mutant combinations elucidates regulation and function of the overlap of hunchback and Krüppel gene expression in the Drosophila blastoderm embryo

1989 • 68 citations

Region-specific defects in l(1)giant embryos of Drosophila melanogaster

1987 • 58 citations

Role of Gap Genes in Early Drosophila Development

1990 • 34 citations

DNA-Binding Proteins in Drosophila Development

1990 • 1 citations