Transcriptional repression of eukaryotic promoters

Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element

1988 • 983 citations

The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements

1988 • 679 citations

Negative effect of the transcriptional activator GAL4

1988 • 672 citations

Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist

1989 • 599 citations

Steroid hormone receptors compete for factors that mediate their enhancer function

1989 • 580 citations

Negative Regulation by Glucocorticoids Through Interference with a cAMP Responsive Enhancer

1988 • 502 citations

Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene.

1988 • 485 citations

A repressor (MATα2 product) and its operator control expression of a set of cell type specific genes in yeast

1985 • 368 citations

Synergistic activation and repression of transcription by Drosophila homeobox proteins

1989 • 353 citations

The yeast cell-type-specific repressor α2 acts cooperatively with a non-cell-type-specific protein

1988 • 348 citations

Transcriptional activation and repression by Ultrabithorax proteins in cultured Drosophila cells

1989 • 291 citations

A protein involved in minichromosome maintenance in yeast binds a transcriptional enhancer conserved in eukaryotes.

1989 • 239 citations

Steroid receptor-mediated inhibition of rat prolactin gene expression does not require the receptor DNA-binding domain

1988 • 238 citations

Activation and repression of transcription by homoeodomain-containing proteins that bind a common site

1988 • 217 citations

The yeast transcription activator PRTF, a homolog of the mammalian serum response factor, is encoded by the MCM1 gene.

1989 • 160 citations

Co-localization of elements required for phorbol ester stimulation and glucocorticoid repression of proliferin gene expression.

1989 • 154 citations

Flexibility of the yeast alpha 2 repressor enables it to occupy the ends of its operator, leaving the center free.

1988 • 150 citations

A purified Drosophila homeodomain protein represses transcription in vitro

1989 • 142 citations

Transcriptional inhibition by a glucocorticoid receptor-β-galactosidase fusion protein

1988 • 129 citations

Identification of a DNA segment that is necessary and sufficient for alpha-specific gene control in Saccharomyces cerevisiae: implications for regulation of alpha-specific and a-specific genes.

1988 • 95 citations