Met proto-oncogene product is overexpressed in tumors of p53-deficient mice and tumors of Li-Fraumeni patients.

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1992 • 4,648 citations

The p53 tumour suppressor gene

1991 • 3,871 citations

Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms

1990 • 3,720 citations

p53 function and dysfunction

1992 • 1,918 citations

p53: oncogene or anti-oncogene?

1990 • 812 citations

p53 functions as a cell cycle control protein in osteosarcomas.

1990 • 774 citations

Cellular immortalization by a cDNA clone encoding the transformation-associated phosphoprotein p53

1984 • 606 citations

Mechanism of met oncogene activation

1986 • 551 citations

Spontaneous and carcinogen–induced tumorigenesis in p53–deficient mice

1993 • 537 citations

Tyrosine kinase receptor indistinguishable from the c-met protein

1989 • 496 citations

Expression of the Met/HGF receptor in normal and neoplastic human tissues.

1991 • 481 citations

In vitro growth characteristics of embryo fibroblasts isolated from p53-deficient mice.

1993 • 471 citations

Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation.

1994 • 363 citations

Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor.

1992 • 316 citations

Hepatocyte growth factor/scatter factor and its receptor, the c-met proto-oncogene product

1993 • 281 citations

Spontaneous abnormalities in normal fibroblasts from patients with Li-Fraumeni cancer syndrome: aneuploidy and immortalization.

1990 • 256 citations

Ubiquitous MyoD transcription at the midblastula transition precedes induction-dependent MyoD expression in presumptive mesoderm of X. laevis

1991 • 248 citations

The met Proto-Oncogene Receptor and Lumen Formation

1992 • 246 citations

Hepatocyte growth factor--scatter factor: mitogen, motogen, and met.

1991 • 234 citations

The Met Proto-Oncogene Mesenchymal to Epithelial Cell Conversion

1994 • 215 citations

Mesodermal Patterning by a Gradient of the Vertebrate Homeobox Gene goosecoid

1994 • 168 citations

p53 and the Li-Fraumeni syndrome

1993 • 151 citations

Met expression and sarcoma tumorigenicity.

1993 • 144 citations

Tumorigenesis induced by coexpression of human hepatocyte growth factor and the human met protooncogene leads to high levels of expression of the ligand and receptor.

1993 • 90 citations

Purified Scatter Factor Stimulates Epithelial and Vascular Endothelial Cell Migration

1990 • 86 citations

Amplification and overexpression of the met gene in spontaneously transformed NIH3T3 mouse fibroblasts.

1986 • 61 citations

Evidence for non-covalent clusters of the c-met proto-oncogene product.

1992 • 48 citations

Several mutant p53 proteins detected in cancer-prone families with Li-Fraumeni syndrome exhibit transdominant effects on the biochemical properties of the wild-type p53.

1993 • 44 citations

Tyrosine kinase receptors in the control of epithelial growth and morphogenesis during development

1993 • 41 citations

Selection for transformation and met protooncogene amplification in NIH 3T3 fibroblasts using tumor necrosis factor alpha.

1990 • 19 citations