The subfornical organ: a central nervous system site for actions of circulating leptin

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

Weight-Reducing Effects of the Plasma Protein Encoded by the obese Gene

1995 • 4,457 citations

Effects of the obese Gene Product on Body Weight Regulation in ob / ob Mice

1995 • 4,057 citations

Identification and expression cloning of a leptin receptor, OB-R

1995 • 3,498 citations

Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks

1995 • 3,302 citations

Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

2001 • 2,288 citations

Leptin enters the brain by a saturable system independent of insulin

1996 • 1,210 citations

Physiological response to long-term peripheral and central leptin infusion in lean and obese mice

1997 • 1,043 citations

Distributions of leptin receptor mRNA isoforms in the rat brain

1998 • 1,011 citations

Divergent Signaling Capacities of the Long and Short Isoforms of the Leptin Receptor

1997 • 907 citations

Localization of leptin receptor mRNA and the long form splice variant (Ob‐Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization

1996 • 879 citations

Activation of Downstream Signals by the Long Form of the Leptin Receptor

2000 • 800 citations

Leptin Signaling, Adiposity, and Energy Balance

2002 • 769 citations

Leptin Signaling in the Central Nervous System and the Periphery

2004 • 560 citations

The efferent projections of the subfornical organ of the rat: A circumventricular organ within a neural network subserving water balance

1981 • 548 citations

Leptin responsiveness restored by amylin agonism in diet-induced obesity: Evidence from nonclinical and clinical studies

2008 • 406 citations

The Neuroanatomical Axis for Control of Energy Balance

2002 • 390 citations

Evidence That the Caudal Brainstem Is a Target for the Inhibitory Effect of Leptin on Food Intake

2002 • 374 citations

An HRP study of the connections of the subfornical organ of the rat

1982 • 345 citations

Obesity-prone rats have normal blood-brain barrier transport but defective central leptin signaling before obesity onset

2004 • 264 citations

In vitro autoradiographic localization of amylin binding sites in rat brain

1994 • 264 citations

Regulation of Jak Kinases by Intracellular Leptin Receptor Sequences

2002 • 228 citations

Critical role of STAT3 in leptin's metabolic actions

2006 • 205 citations

Brain Stem Is a Direct Target for Leptin’s Action in the Central Nervous System

2002 • 202 citations

Leptin-Induced Nuclear Translocation of STAT3 Immunoreactivity in Hypothalamic Nuclei Involved in Body Weight Regulation

2001 • 192 citations

The Long Form of the Leptin Receptor (OB-Rb) Is Widely Expressed in the Human Brain

2000 • 156 citations

Expression of the leptin receptor in rat and human nodose ganglion neurones

2002 • 122 citations

Electrophysiological Actions of Peripheral Hormones on Melanocortin Neurons

2003 • 118 citations

Neuropeptide Y Y1 receptor mRNA in rodent brain: Distribution and colocalization with melanocortin-4 receptor

2004 • 116 citations

Specific Physiological Roles for Signal Transducer and Activator of Transcription 3 in Leptin Receptor-Expressing Neurons

2007 • 106 citations

Peripheral amylin activates circumventricular organs expressing calcitonin receptor a/b subtypes and receptor-activity modifying proteins in the rat

2003 • 94 citations

The Subfornical Organ: A Central Target for Circulating Feeding Signals

2006 • 93 citations

Making sense of it: roles of the sensory circumventricular organs in feeding and regulation of energy homeostasis.

2007 • 88 citations

Comparative distribution off receptors for amylin and the related peptides calcitonin gene related peptide and calcitonin in rat and monkey brain

1995 • 87 citations

Morphology and function of capillary networks in subregions of the rat tuber cinereum

1992 • 84 citations

Association of leptin receptor (OB-Rb), NPY and GLP-1 gene expression in the ovine and murine brainstem

1998 • 71 citations

Microarray analysis of the transcriptome of the subfornical organ in the rat: regulation by fluid and food deprivation

2008 • 71 citations

Vascular-brain signaling in hypertension: Role of angiotensin II and nitric oxide

2007 • 61 citations

Expression of Leptin Receptors and Induction of IL-1β Transcript in Glial Cells

2000 • 51 citations

Structural and functional evidence supporting a role for leptin in central neural pathways influencing blood pressure in rats

2005 • 49 citations

A subthreshold persistent sodium current mediates bursting in rat subfornical organ neurones

2000 • 47 citations

Leptin induces cyclooxygenase‐2 via an interaction with interleukin‐1β in the rat brain

2006 • 43 citations

Prokineticin 2 Modulates the Excitability of Subfornical Organ Neurons

2004 • 42 citations

Pharmacological characterisation of amylin-related peptides activating subfornical organ neurones

1999 • 42 citations

Circumventricular Organs: Gateways to the BrainLeptin Receptors In Hypothalamus And Circumventricular Organs

2001 • 35 citations

Lateral hypothalamic area stimulation excites neurons in the region of the subfornical organ with efferent projections to the hypothalamic paraventricular nucleus in the rat

1986 • 34 citations

Efferent pathways from the region of the subfornical organ to hypothalamic paraventricular nucleus: an electrophysiological study in the rat

1986 • 33 citations

Quantitative fine structure of capillaries in subregions of the rat subfornical organ

1990 • 32 citations

Characterization of [3H]Harmane Binding to Rat Whole Brain Membranes

2003 • 24 citations

Arcuate nucleus inputs onto subfornical organ neurons that respond to plasma hypernatremia and angiotensin II

1996 • 16 citations

Subthreshold oscillations of membrane potential of rat subfornical organ neurons

2007 • 11 citations

Neurotensin projections to subfornical organ from arcuate nucleus

1996 • 10 citations