Circumventricular Organs: Gateways to the BrainLeptin Receptors In Hypothalamus And Circumventricular Organs

Positional cloning of the mouse obese gene and its human homologue

1994 • 12,975 citations

Weight-Reducing Effects of the Plasma Protein Encoded by the obese Gene

1995 • 4,457 citations

Effects of the obese Gene Product on Body Weight Regulation in ob / ob Mice

1995 • 4,057 citations

Identification and expression cloning of a leptin receptor, OB-R

1995 • 3,498 citations

Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks

1995 • 3,302 citations

Abnormal splicing of the leptin receptor in diabetic mice

1996 • 2,361 citations

Evidence That the Diabetes Gene Encodes the Leptin Receptor: Identification of a Mutation in the Leptin Receptor Gene in db/db Mice

1996 • 2,185 citations

The role of neuropeptide Y in the antiobesity action of the obese gene product

1995 • 1,521 citations

Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin

1996 • 1,505 citations

Identification of targets of leptin action in rat hypothalamus.

1996 • 1,502 citations

STATs: Signal Transducers and Activators of Transcription

1996 • 1,414 citations

NEUROPEPTIDE Y AND HUMAN PANCREATIC POLYPEPTIDE STIMULATE FEEDING BEHAVIOR IN RATS

1984 • 1,274 citations

Leptin enters the brain by a saturable system independent of insulin

1996 • 1,210 citations

Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y

1996 • 1,020 citations

Diabetes, a New Mutation in the Mouse

1966 • 966 citations

A receptor subtype involved in neuropeptide-Y-induced food intake

1996 • 892 citations

Localization of leptin receptor mRNA and the long form splice variant (Ob‐Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization

1996 • 879 citations

Specificity of Leptin Action on Elevated Blood Glucose Levels and Hypothalamic Neuropeptide Y Gene Expression in ob/ob Mice

1996 • 873 citations

Neuropeptide Y chronically injected into the hypothalamus: A powerful neurochemical inducer of hyperphagia and obesity

1986 • 856 citations

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors.

1996 • 820 citations

Attenuation of the Obesity Syndrome of ob/ob Mice by the Loss of Neuropeptide Y

1996 • 814 citations

Defective STAT signaling by the leptin receptor in diabetic mice.

1996 • 803 citations

Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues

1997 • 771 citations

Leptin Receptor Immunoreactivity in Chemically Defined Target Neurons of the Hypothalamus

1998 • 753 citations

Effects of parabiosis of obese with diabetes and normal mice

1973 • 728 citations

Crystal structure of the obese protein Ieptin-E100

1997 • 658 citations

Novel B219/OB receptor isoforms: Possible role of leptin in hematopoiesis and reproduction

1996 • 629 citations

An arcuato-paraventricular and -dorsomedial hypothalamic neuropeptide Y-containing system which lacks noradrenaline in the rat

1985 • 523 citations

The OB Protein (Leptin) Pathway - A Link Between Adipose Tissue Mass and Central Neural Networks

1996 • 517 citations

Coexpression of Leptin Receptor and Preproneuropeptide Y mRNA in Arcuate Nucleus of Mouse Hypothalamus

1996 • 473 citations

The Leptin Receptor Activates Janus Kinase 2 and Signals for Proliferation in a Factor-Dependent Cell Line

1997 • 315 citations

The hypothalamic arcuate nucleus-median eminence complex: Immunohistochemistry of transmitters, peptides and DARPP-32 with special reference to coexistence in dopamine neurons

1986 • 231 citations

The hypothalamic arcuate nucleus-median eminence complex: Immunohistochemistry of transmitters, peptides and DARPP-32 with special reference to coexistence in dopamine neurons

1986 • 210 citations

Endorphinergic mechanisms in the control of food and water intake

1981 • 183 citations

Localization of Leptin Receptor (Ob-R) Messenger Ribonucleic Acid in the Rodent Hindbrain*

1998 • 165 citations

Expression of leptin receptor mRNA in the hypothalamic arcuate nucleus - relationship with NPY neurones

1996 • 164 citations

Localization of leptin receptor mRNA expression in mouse brain

1996 • 159 citations

Localization of neuropeptide Y Y1 receptors in the rat nervous system with special reference to somatic receptors on small dorsal root ganglion neurons.

1994 • 142 citations

Regulation of leptin receptor and NPY gene expression in hypothalamus of leptin‐treated obese (ob/ob) and cold‐exposed lean mice

1997 • 130 citations

The Loop System Between Neuropeptide Y and Leptin in Normal and Obese Rodents

1996 • 93 citations

Morphology and function of capillary networks in subregions of the rat tuber cinereum

1992 • 84 citations

Leptin injected into the fourth ventricle inhibits gastric emptying

1998 • 48 citations

Neuropeptide Y stimulates β-endorphin release in the basal hypothalamus: role of gonadal steroids

1995 • 30 citations

Monosodium Glutamate (MSG) Lesions

1991 • 19 citations